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2721por Cheng, Kaiying, Xu, Hong, Chen, Xuanyi, Wang, Liangyan, Tian, Bing, Zhao, Ye, Hua, Yuejin“…The resection of DNA strand with a 5´ end at double-strand breaks is an essential step in recombinational DNA repair. …”
Publicado 2016
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2722por Duong, Dinh Thuy, Singh, Shalini, Bagheri, Mojtaba, Verma, Navin Kumar, Schmidtchen, Artur, Malmsten, Martin“…Effects of oligotryptophan end-tagging on the uptake of arginine-rich peptides into melanoma cells was investigated under various conditions and compared to that into non-malignant keratinocytes, fibroblasts, and erythrocytes, also monitoring resulting cell toxicity. …”
Publicado 2016
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2723por de Marchi, Rémi, Sorel, Maud, Mooney, Brian, Fudal, Isabelle, Goslin, Kevin, Kwaśniewska, Kamila, Ryan, Patrick T., Pfalz, Marina, Kroymann, Juergen, Pollmann, Stephan, Feechan, Angela, Wellmer, Frank, Rivas, Susana, Graciet, Emmanuelle“…Here, we demonstrate that the N-end rule pathway, a subset of the ubiquitin/proteasome system, regulates the defense against a wide range of bacterial and fungal pathogens in the model plant Arabidopsis thaliana. …”
Publicado 2016
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2724
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2725“…Non-homologous end joining (NHEJ) is a major DNA double-strand break (DSB) repair mechanism. …”
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2726por Linnell, John D. C., Trouwborst, Arie, Boitani, Luigi, Kaczensky, Petra, Huber, Djuro, Reljic, Slaven, Kusak, Josip, Majic, Aleksandra, Skrbinsek, Tomaz, Potocnik, Hubert, Hayward, Matt W., Milner-Gulland, E. J., Buuveibaatar, Bayarbaatar, Olson, Kirk A., Badamjav, Lkhagvasuren, Bischof, Richard, Zuther, Steffen, Breitenmoser, UrsEnlace del recurso
Publicado 2016
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2727por Weng, Shih-Feng, Jan, Ren-Long, Chang, Chun, Wang, Jhi-Joung, Su, Shih-Bin, Huang, Chien-Cheng, Tseng, Sung-Huei, Chang, Yuh-Shin“…This study is a retrospective, nationwide, matched cohort study to investigate the risk of band keratopathy following end-stage renal disease (ESRD). The study cohort included 94,039 ESRD on-dialysis patients identified by the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM), code 585 and registered between January 2000 to December 2009 at the Taiwan National Health Insurance Research Database. …”
Publicado 2016
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2728“…World leaders have committed to ending AIDS by 2030, but stigma and discrimination remain significant obstacles. …”
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2729“…However, the role of BRCA1 in the other two DSB repair pathways, classical non-homologous end-joining (C-NHEJ) and alternative NHEJ (A-NHEJ), remains unclear. …”
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2730“…By analysing their intronome we provide evidence of selection for STOP codons close to the intronic 5′ end, and show that the beginning of introns are selected for significantly high translation, presumably to reduce translation and metabolic costs in cases of non-spliced introns. …”
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2731“…Cells have evolved two major competing DSB repair mechanisms: Homologous recombination (HR) and non-homologous end joining (NHEJ). HR is initiated by DNA-end resection, an evolutionarily conserved process that generates stretches of single-stranded DNA tails that are no longer substrates for religation by the NHEJ machinery. …”
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2732por Hung, Tsung-Hsing, Tsai, Chen-Chi, Tseng, Kuo-Chih, Tseng, Chih -Wei, Hsieh, Yu-Hsi, Tsai, Chih-Chun, Lee, Hsing-Feng“…Limited data exist with which to evaluate the long-term mortality of end-stage renal disease (ESRD) in cirrhotic patients with or without complications. …”
Publicado 2016
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2733por Davies, Joanna M, Gao, Wei, Sleeman, Katherine E, Lindsey, Katie, Murtagh, Fliss E, Teno, Joan M, Deliens, Luc, Wee, Bee, Higginson, Irene J, Verne, Julia“…Palliative and end of life care is essential to healthcare systems worldwide, yet a minute proportion of research funding is spent on palliative and end of life care research. …”
Publicado 2016
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2734“…Herein, we describe a case of TTE with blindly ending vas and persistent Mόllerian duct syndrome in a 2-year-old child. …”
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2735“…BACKGROUND: Women with PCOS have elevated levels of the harmful Advanced Glycation End Products (AGEs), which are highly reactive molecules formed after glycation of lipids and proteins. …”
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2736“…This study describes the synthesis of 1,2,3‐triazole adducts from their corresponding PEG azides via a convenient, mild click reaction, which facilitates straightforward NMR‐based quantitative end‐group analysis.This method was found to be compatible with many examples of bifunctional azido PEGs with molecular weights ranging from 2 to 18 kDa bearing a variety of functional groups. © 2016 The Authors. …”
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2737por Lønning, Kjersti, Midtvedt, Karsten, Leivestad, Torbjørn, Reisæter, Anna V., Line, Pål-Dag, Hartmann, Anders, Heldal, Kristian“…Data were retrieved from the Norwegian Renal Registry in the end of October 2015. Graft and patient survivals were compared with recipients aged 70 to 79 years at transplantation. …”
Publicado 2016
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2738“…End stage renal disease (ESRD) in infants has particular features in terms of etiologies and therapeutic modalities. …”
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2739por Hayashi, Rippei, Schnabl, Jakob, Handler, Dominik, Mohn, Fabio, Ameres, Stefan L., Brennecke, Julius“…Formation of piRNA 3' ends is poorly understood. Here, we find that two genetically and mechanistically distinct pathways generate piRNA 3' ends in Drosophila. …”
Publicado 2016
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2740