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  1. 3441
  2. 3442
    por Darmon, Sarah K., Lutz, Carol S.
    Publicado 2012
    “…Almost all eukaryotic mRNAs possess 3′ ends with a polyadenylate (poly(A)) tail. This poly(A) tail is not encoded in the genome but is added by the process of polyadenylation. …”
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  3. 3443
    “…Here, we show that ablating XRCC4's affinity for XLF results in DNA repair deficits including a surprising deficit in VDJ coding, but not signal end joining. These data are consistent with a model whereby XRCC4/XLF complexes hold DNA ends together—stringently required for coding end joining, but dispensable for signal end joining. …”
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  4. 3444
  5. 3445
    “…A distinction is made between diastolic HF (preserved left ventricular ejection fraction (LVEF)) and systolic HF (reduced LVEF). Advanced glycation end-products (AGEs) are crystallized proteins that accumulate during ageing, but are particularly increased in patients with diabetes mellitus and in patients with renal failure. …”
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  6. 3446
    por McLean, Malcolm A, Tirosh, Itay
    Publicado 2011
    “…The pattern of GC-skew is asymmetrical: the coding strand of genes is typically C-biased at the 5' ends but G-biased at the 3' ends, with intermediate skews at the middle of genes. …”
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  7. 3447
  8. 3448
    “…BACKGROUND: In India the incidence of end stage renal disease (ESRD) is increasing day by day and the option for the treatment of ESRD is dialysis or transplantation. …”
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  9. 3449
    “…End-stage osteoarthritis of the ankle is a disabling problem, particularly in elderly patients who experience an overall loss of mobility and functional impairment and who then need compensatory adaption. …”
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  10. 3450
  11. 3451
    por Mortazavi, F., Maleki, M.
    Publicado 2012
    “…Outcome of end-stage renal disease (ESRD) in children has considerably improved since the development of dialysis and kidney transplantation. …”
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  12. 3452
  13. 3453
    “…BACKGROUND: The extent and the distribution of end stage kidney disease (ESKD) in Libya have not been reported despite provision of dialysis over 4 decades. …”
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  14. 3454
    “…The complementarity of 16-nt end regions of 4.5SI RNA proved to contribute to its stability in cells, whereas the lack of such complementarity in 4.5SH RNA caused its rapid decay. …”
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  15. 3455
    “…This open label, multicentric, comparative clinical trial was done to compare the efficacy and tolerability of two sevelamer formulations, sevelamer carbonate, and sevelamer hydrochloride, in the treatment of hyperphosphatemia in Indian end stage renal disease (ESRD) patients. A total of 97 ESRD patients on hemodialysis, were enrolled. …”
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  16. 3456
    “…INTRODUCTION: The provision of an effective apical seal is an essential factor when choosing an appropriate material for success of root-end surgeries. Root-end resection, preparation and obturation should provide an adequate apical seal. …”
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  17. 3457
    “…Our findings indicate that age-related decline in the brain begins as soon as the end of adolescence, a novel finding has important clinical and social implications for public health and welfare.…”
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  18. 3458
  19. 3459
  20. 3460
    “…BACKGROUND AND PURPOSE: Delirium at the end of life is common and can have serious consequences on an older person’s quality of life and death. …”
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