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  1. 4501
    “…Recent advances reveal mRNA 3′end processing as a highly regulated process that fine-tunes posttranscriptional gene expression. …”
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    mRNA 3′end processing: A tale of the tail reaches the clinic
  2. 4502
    “…Here we develop novel genetic and molecular tools to modify the structure of DSB ends and demonstrate that ATM is indeed required for efficient and accurate DSB repair, preventing cell death and genome instability, but exclusively when the ends are irreversibly blocked. …”
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    ATM specifically mediates repair of double-strand breaks with blocked DNA ends
  3. 4503
    por Lau, Tsang, Ahmad, Jawad
    Publicado 2013
    “…The Model for End-Stage Liver Disease (MELD) score incorporates serum bilirubin, creatinine, and the international normalized ratio (INR) into a formula that provides a continuous variable that is a very accurate predictor of 90-day mortality in patients with cirrhosis. …”
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    Clinical applications of the Model for End-Stage Liver Disease (MELD) in hepatic medicine
  4. 4504
    “…Morphological and molecular features of MH were detected in end-stage ICM as well as in end-stage DCM LV, despite epicardial coronary artery patency and lower fibrosis in DCM hearts. …”
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    Regional mapping of myocardial hibernation phenotype in idiopathic end-stage dilated cardiomyopathy
  5. 4505
    “…Elucidating the sites and mechanisms of sRAGE action in the healthy state is vital to better understand the biological importance of the receptor for advanced glycation end products (RAGE). Previous studies in animal models of disease have demonstrated that exogenous sRAGE has an anti-inflammatory effect, which has been reasoned to arise from sequestration of pro-inflammatory ligands away from membrane-bound RAGE isoforms. …”
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    Clearance Kinetics and Matrix Binding Partners of the Receptor for Advanced Glycation End Products
  6. 4506
    “…Background: Advanced glycation end-products (AGEs) can accumulate in organs and tissues during ageing and diabetes. …”
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    Increased Levels of Circulating Advanced Glycation End-Products in Menopausal Women with Osteoporosis
  7. 4507
    “…Herein we present a rare ureteric duplication anomaly; blind ending bifid ureter with calculi which is asymptomatic unless complicated by infection, reflux, calculi or malignancy. …”
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    US and MDCT findings in a caudal blind ending bifid ureter with calculi
  8. 4508
    “…From images at high spatial and temporal resolution, it has been inferred that the regulation of filament barbed ends plays a central role in choreographing actin organization and turnover. …”
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    The availability of filament ends modulates actin stochastic dynamics in live plant cells
  9. 4509
    “…In this study, we evaluated the antiemetic efficacy of propofol administered at the end of surgery in highly susceptible patients undergoing a laparoscopy-assisted vaginal hysterectomy. …”
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    Antiemetic effect of propofol administered at the end of surgery in laparoscopic assisted vaginal hysterectomy
  10. 4510
    “…Myocardial ischemia can prolong QT dispersion and increase the risk of cardiac arrhythmias as well as sudden cardiac arrests. Also, T wave peak–to–end (Tp-Te) interval dispersion, which provides a valuable index of transmural dispersion of repolarization, can trigger the arrhythmia. …”
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    QT Dispersion and T Wave Peak–to–end Interval Dispersion in Children with Kawasaki Disease
  11. 4511
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    NK cell therapy for end-stage cancerous patient: A case study
  12. 4512
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    Receptor for advanced glycation end‐products‐mediated inflammation and diabetic vascular complications
  13. 4513
    “…Extensive intracellular and extracellular formation of advanced glycation end‐products (AGE) is considered a causative factor in vascular injuries in diabetes. …”
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    Controlling the receptor for advanced glycation end‐products to conquer diabetic vascular complications
  14. 4514
    por Ossareh, Shahrzad
    Publicado 2014
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    Clinical and economic aspects of sevelamer therapy in end-stage renal disease patients
  15. 4515
    “…In contrast to previous models, we show that ALIX is recruited transiently at the end of Gag assembly, and that most ALIX molecules are recycled into the cytosol as the virus buds, although a subset remains within the virion. …”
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    ALIX Is Recruited Temporarily into HIV-1 Budding Sites at the End of Gag Assembly
  16. 4516
    “…Patient: Female, 41 Final Diagnosis: Ovarian carcinoma Symptoms: Ascites • hepatomegaly • weight loss Medication: — Clinical Procedure: — Specialty: Oncology OBJECTIVE: Unusual or unexpected effect of treatment BACKGROUND: The aim of this case report is to present the results of treatment of end-stage ovarian carcinoma in a 41-year-old women using weight loss therapy. …”
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    Weight change therapy as a potential treatment for end-stage ovarian carcinoma
  17. 4517
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    Impact of Hemodialysis on Dyspnea and Lung Function in End Stage Kidney Disease Patients
  18. 4518
    “…INTRODUCTION: End-stage renal disease (ESRD) is associated with an increased propensity for critical illness, but whether ESRD is independently associated with a greater risk of death after major surgical procedures is unclear. …”
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    End-stage renal disease and outcome in a surgical intensive care unit
  19. 4519
    por Li, Li Bin
    Publicado 2013
    “…How to care for patients at the end of life is not only a medical problem but also a social, ethical, and legal issue. …”
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    Clinical review: Ethics and end-of-life care for critically ill patients in China
  20. 4520
    “…CONCLUSIONS: A low continuous dose of estrogen improves shell strength but not bone strength in laying hens at the end of the laying period.…”
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    Exogenous estradiol improves shell strength in laying hens at the end of the laying period
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