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  1. 5261
    “…One under-researched area is how patients and family caregivers manage the complexity of end-of-life therapeutic medicine regimens. In this position paper the authors bring attention to the significant strain that patients and family caregivers experience when navigating and negotiating this aspect of palliative and end-of-life care. …”
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    Managing medicines at the end of life: a position paper for health policy and practice
  2. 5262
    “…AVAILABILITY AND IMPLEMENTATION: The ENDS is freely available online at https://irscope.shinyapps.io/ENDS/ and source codes can be obtained from https://github.com/AmiryousefiLab/ENDS. …”
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    The ENDS of assumptions: an online tool for the epistemic non-parametric drug–response scoring
  3. 5263
    “…How LMI shapes or guides patient-centred, end-of-life care remains unclear. The aim of this study was to examine possible associations between LMI and certain aspects of end-of-life care practices in LTCC, such as nurse-documented patient experiences of pain, and prescription and administration of medication. …”
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    Levels of Medical Intervention and End-of-Life Practices in Long-Term Care Centres
  4. 5264
    “…Our objective was to assess the safety of remdesivir in patients with end-stage renal failure and evaluate the outcome of this vulnerable group. …”
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    Safety and Tolerability of Remdesivir in Patients with End-stage Renal Disease on Maintenance Hemodialysis
  5. 5265
    “…The scientific community has to abandon some dead ends and explore new paths that will improve our understanding of individual species, traits, and the functioning of benthic ecosystems.…”
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    Biological traits approaches in benthic marine ecology: Dead ends and new paths
  6. 5266
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    Hydralazine–Isosorbide Dinitrate Use in Patients With End-Stage Kidney Disease on Dialysis
  7. 5267
    “…BACKGROUND: Genetic improvement of end-use quality is an important objective in wheat breeding programs to meet the requirements of grain markets, millers, and bakers. …”
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    Genetic architecture of end-use quality traits in soft white winter wheat
  8. 5268
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    Helicobacter pylori genomes reveal Paleolithic human migration to the east end of Asia
  9. 5269
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    224 Ends of Endemics: Capturing Viral UTRs in Clinically Relevant Arbovirus Samples
  10. 5270
    por Ross, Charles H.
    Publicado 1876
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    Oldboy Brother’s Nearest Relative: A Tootletum Tale with a Sentimental Ending
  11. 5271
    “…Carotenoids have antioxidant properties, and the accumulation of advanced glycation end products (AGEs) is associated with reactive oxygen species production; they have attracted attention as factors predictive of the onset and progression in glaucoma. …”
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    Fingertip-Measured Skin Carotenoids and Advanced Glycation End Product Levels in Glaucoma
  12. 5272
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    Admission Code Status and End-of-life Care for Hospitalized Patients With COVID-19
  13. 5273
    “…Canonical non-homologous end joining (C-NHEJ) factors can assemble into a long-range (LR) complex with DNA ends relatively far apart that contains DNAPKcs, XLF, XRCC4, LIG4, and the KU heterodimer and a short-range (SR) complex lacking DNAPKcs that has the ends positioned for ligation. …”
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    The importance of DNAPKcs for blunt DNA end joining is magnified when XLF is weakened
  14. 5274
    “…Objective: To examine conversations among JUUL users on Reddit related to restrictions on flavored ENDS and the shifting policy landscape. Methods: Posts and comments (n = 166,169) between May 2019 and May 2020 on the subreddit r/JUUL were scraped using pushshift.io API. …”
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    Discussions of Flavored ENDS Sales Restrictions: Themes Related to Circumventing Policies on Reddit
  15. 5275
    “…Here, we show that the microtubule plus-end tracking protein Bik1—the budding yeast ortholog of CLIP-170—is essential for chromosome congression. …”
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    The microtubule plus-end tracking protein Bik1 is required for chromosome congression
  16. 5276
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    Palliative Sedation in End-of-Life Patients in Eastern Asia: A Narrative Review
  17. 5277
    “…This study aimed to develop a simplified model for predicting end-stage kidney disease (ESKD) in patients with diabetes. …”
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    A simplified prediction model for end-stage kidney disease in patients with diabetes
  18. 5278
    por Holmberg, Bodil, Godskesen, Tove
    Publicado 2022
    “…Although dignity is a commonly used concept and a core value of end-of-life care, it is assumed to be complex, ambiguous, and multivalent. …”
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    Dignity in bodily care at the end of life in a nursing home: an ethnographic study
  19. 5279
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    Comorbidity is not associated with dialysis modality choice in patients with end‐stage kidney disease
  20. 5280
    por Chen, Bo-Ruei, Sleckman, Barry P.
    Publicado 2022
    “…There are two major pathways dedicated to DSB repair: homologous recombination (HR) and non-homologous end joining (NHEJ). The decision of deploying HR or NHEJ to repair DSBs largely depends on the structures of broken DNA ends. …”
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    The regulation of DNA end resection by chromatin response to DNA double strand breaks
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