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721por Geisinger, Jonathan M., Turan, Sören, Hernandez, Sophia, Spector, Laura P., Calos, Michele P.“…The CRISPR/Cas9 system facilitates precise DNA modifications by generating RNA-guided blunt-ended double-strand breaks. We demonstrate that guide RNA pairs generate deletions that are repaired with a high level of precision by non-homologous end-joining in mammalian cells. …”
Publicado 2016
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723por Ramirez-Rios, Sacnicte, Denarier, Eric, Prezel, Eléa, Vinit, Angélique, Stoppin-Mellet, Virginie, Devred, François, Barbier, Pascale, Peyrot, Vincent, Sayas, Carmen Laura, Avila, Jesus, Peris, Leticia, Andrieux, Annie, Serre, Laurence, Fourest-Lieuvin, Anne, Arnal, Isabelle“…Proper regulation of microtubule dynamics is essential for cell functions and involves various microtubule-associated proteins (MAPs). Among them, end-binding proteins (EBs) accumulate at microtubule plus ends, whereas structural MAPs bind along the microtubule lattice. …”
Publicado 2016
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724por Reid, Dylan A., Conlin, Michael P., Yin, Yandong, Chang, Howard H., Watanabe, Go, Lieber, Michael R., Ramsden, Dale A., Rothenberg, Eli“…The nonhomologous end-joining (NHEJ) pathway is the primary repair pathway for DNA double strand breaks (DSBs) in humans. …”
Publicado 2017
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725por Zhang, Yuhua, Liu, Zhenjie, Shen, Guoliang, Zhang, Jungang, Assa, Carmel Rebecca, Hong, Defei“…PATIENT CONCERNS: Here we present a case of SAA treated by laparoscopic aneurysmectomy with end-to-end anastomosis. DIAGNOSES: A 40-year-old woman was incidentally found to have an asymptomatic distal SAA. …”
Publicado 2017
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727“…PURPOSE: The aim of this project was to design and manufacture a cost‐effective end‐to‐end (E2E) phantom for quantifying the geometric and dosimetric accuracy of a linear accelerator based, multi‐target single‐isocenter (MTSI) frameless stereotactic radiosurgery (SRS) technique. …”
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728por Hansen, Cecilie, Drinkwater, Kenneth F., Jähkel, Anne, Fulton, Elizabeth A., Gorton, Rebecca, Skern-Mauritzen, Mette“…Using end-to-end models for ecosystem-based management requires knowledge of the structure, uncertainty and sensitivity of the model. …”
Publicado 2019
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729por Howarth, Holly M., Alaziz, Turki, Nicolds, Brogan, O’Connor, Shawn, Shah, Sameer B.“…End-to-end repair under no or low tension leads to improved outcomes for transected nerves with short gaps, compared to repairs with a graft. …”
Publicado 2019
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730“…PURPOSE: This report describes the laparoscopic end-to-end biliary reconstruction with T-tube for transected bile duct injury (BDI) during laparoscopic cholecystectomy. …”
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731“…We propose a two-step ligand exchange for the selective end-functionalization of gold nanorods (AuNR) by thiolated cyclodextrin (CD) host molecules. …”
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732por Kumar, Sunil, Navariya, Shiv C., Bhirud, Deepak P., Ranjan, Satish K., Mittal, Ankur, Mammen, Kim J.“…It was recognised intraoperatively and an end to end anastomosis was done by laparotomy. DISCUSSION: SMA injury is rarely encountered in surgical practice. …”
Publicado 2019
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733“…Endogenously-arising DNA double-strand breaks (DSBs) rarely harbor canonical 5′-phosphate, 3′-hydroxyl moieties at the ends, which are, regardless of the pathway used, ultimately required for their repair. …”
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734“…This paper introduced a deep semantic segmentation method that combined a deep-convolution neural network with the fully connected conditional random field to form an end-to-end connection. On the basis of Resnet, it first roughly segmented a multisource remote-sensing image as input by the deep convolutional neural network. …”
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735“…RESULTS: The total count of reported signs and symptoms through open-ended and close-ended question was 164 and 529 reports, respectively. …”
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736por Blanco, Bego, Solozabal, Rubén, Sanchoyerto, Aitor, López-Cuadrado, Javier, Jimeno, Elisa, Catalan-Cid, Miguel“…This paper describes the design and deployment of an intelligent orchestration cycle to manage end-to-end slices on a NFV architecture. This novel tool includes the monitoring of the network elements at different levels and the processing of the gathered data to produce the corresponding alert mitigation actions.…”
Publicado 2020
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737“…To the best of the authors’ knowledge, this is the first dataset proposed for Urdu text detection, recognition or end-to-end text recognition in natural scene images. …”
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738“…In this paper, we describe a novel end-to-end deep learning-based method for generating compact representations of in situ hybridization (ISH) images, which are invariant-to-translation. …”
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739por Khan, Khalil, Attique, Muhammad, Syed, Ikram, Sarwar, Ghulam, Irfan, Muhammad Abeer, Khan, Rehan Ullah“…In this paper we propose a unified framework for face image analysis through end-to-end semantic face segmentation. The proposed framework contains a set of stack components for face understanding, which includes head pose estimation, age classification, and gender recognition. …”
Publicado 2019
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740por Compton, Austin, Liang, Jiangtao, Chen, Chujia, Lukyanchikova, Varvara, Qi, Yumin, Potters, Mark, Settlage, Robert, Miller, Dustin, Deschamps, Stéphane, Mao, Chunhong, Llaca, Victor, Sharakhov, Igor V., Tu, Zhijian“…This 172.6 Mbps female assembly, which we call AalbS3, is obtained by scaffolding polished large contigs (contig N50 = 13.7 Mbps) into three chromosomes. All chromosome arms end with telomeric repeats, which is the first in mosquito assemblies and represents a significant step toward the completion of a genome assembly. …”
Publicado 2020
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