CD8 lymphocytes mitigate HIV-1 persistence in lymph node follicular helper T cells during hyperacute-treated infection

por Baiyegunhi, Omolara O., Mann, Jaclyn, Khaba, Trevor, Nkosi, Thandeka, Mbatha, Anele, Ogunshola, Funsho, Chasara, Caroline, Ismail, Nasreen, Ngubane, Thandekile, Jajbhay, Ismail, Pansegrouw, Johan, Dong, Krista L., Walker, Bruce D., Ndung’u, Thumbi, Ndhlovu, Zaza M.
Publicado 2022

HIV specific CD8(+) T(RM)-like cells in tonsils express exhaustive signatures in the absence of natural HIV control

por Fardoos, Rabiah, Nyquist, Sarah K., Asowata, Osaretin E., Kazer, Samuel W., Singh, Alveera, Ngoepe, Abigail, Giandhari, Jennifer, Mthabela, Ntombifuthi, Ramjit, Dirhona, Singh, Samita, Karim, Farina, Buus, Søren, Anderson, Frank, Porterfield, J. Zachary, Sibiya, Andile L., Bipath, Rishan, Moodley, Kumeshan, Kuhn, Warren, Berger, Bonnie, Nguyen, Son, de Oliveira, Tulio, Ndung’u, Thumbi, Goulder, Philip, Shalek, Alex K., Leslie, Alasdair, Kløverpris, Henrik N.
Publicado 2022

Delays in initiating rabies post-exposure prophylaxis among dog bite victims in Wakiso and Kampala districts, Uganda

por Kisaka, Stevens, Makumbi, Fredrick, Majalija, Samuel, Bahizi, Gloria, Thumbi, SM
Publicado 2022

Discrepancy between Mtb-specific IFN-γ and IgG responses in HIV-positive people with low CD4 counts

por Mthembu, Maphe, Bowman, Kathryn A., Davies, Leela R.L., Khuzwayo, Sharon, Mazibuko, Lusanda, Bassett, Thierry, Ramjit, Dirhona, Mhlane, Zoey, Karim, Farina, Alter, Galit, Ndung'u, Thumbi, Wong, Emily B.
Publicado 2023

Genetic variation of the HIV-1 subtype C transmitted/founder viruses long terminal repeat elements and the impact on transcription activation potential and clinical disease outcome...

por Madlala, Paradise, Mkhize, Zakithi, Naicker, Shamara, Khathi, Samukelisiwe P., Maikoo, Shreyal, Gopee, Kasmira, Dong, Krista L., Ndung’u, Thumbi
Publicado 2023

Metabolic and mitochondrial dysregulation in CD4(+) T cells from HIV-positive women on combination anti-retroviral therapy

por Akiso, Matrona, Ameka, Magdalene, Naidoo, Kewreshini, Langat, Robert, Kombo, Janet, Sikuku, Delories, Ndung’u, Thumbi, Altfeld, Marcus, Anzala, Omu, Mureithi, Marianne
Publicado 2023

Progression to AIDS in South Africa Is Associated with both Reverting and Compensatory Viral Mutations

por Huang, Kuan-Hsiang Gary, Goedhals, Dominique, Carlson, Jonathan M., Brockman, Mark A., Mishra, Swati, Brumme, Zabrina L., Hickling, Stephen, Tang, Christopher S. W., Miura, Toshiyuki, Seebregts, Chris, Heckerman, David, Ndung'u, Thumbi, Walker, Bruce, Klenerman, Paul, Steyn, Dewald, Goulder, Philip, Phillips, Rodney, van Vuuren, Cloete, Frater, John
Publicado 2011

Diagnostic Accuracy of Quantitative PCR (Xpert MTB/RIF) for Tuberculous Meningitis in a High Burden Setting: A Prospective Study

por Patel, Vinod B., Theron, Grant, Lenders, Laura, Matinyena, Brian, Connolly, Cathy, Singh, Ravesh, Coovadia, Yacoob, Ndung'u, Thumbi, Dheda, Keertan
Publicado 2013

Design and descriptive epidemiology of the Infectious Diseases of East African Livestock (IDEAL) project, a longitudinal calf cohort study in western Kenya

por de Clare Bronsvoort, Barend Mark, Thumbi, Samuel Mwangi, Poole, Elizabeth Jane, Kiara, Henry, Auguet, Olga Tosas, Handel, Ian Graham, Jennings, Amy, Conradie, Ilana, Mbole-Kariuki, Mary Ndila, Toye, Philip G, Hanotte, Olivier, Coetzer, JAW, Woolhouse, Mark EJ
Publicado 2013

Low Levels of Peripheral CD161++CD8+ Mucosal Associated Invariant T (MAIT) Cells Are Found in HIV and HIV/TB Co-Infection

por Wong, Emily B., Akilimali, Ngomu Akeem, Govender, Pamla, Sullivan, Zuri A., Cosgrove, Cormac, Pillay, Mona, Lewinsohn, David M., Bishai, William R., Walker, Bruce D., Ndung'u, Thumbi, Klenerman, Paul, Kasprowicz, Victoria O.
Publicado 2013

Evaluation of the NucliSens EasyQ v2.0 Assay in Comparison with the Roche Amplicor v1.5 and the Roche CAP/CTM HIV-1 Test v2.0 in Quantification of C-Clade HIV-1 in Plasma

por Muenchhoff, Maximilian, Madurai, Savathee, Hempenstall, Allison Jo, Adland, Emily, Carlqvist, Anna, Moonsamy, Angeline, Jaggernath, Manjeetha, Mlotshwa, Busisiwe, Siboto, Emma, Ndung'u, Thumbi, Goulder, Philip Jeremy Renshaw
Publicado 2014

Neutrophil Effector Functions Are Not Impaired in Duffy Antigen Receptor for Chemokines (DARC)-Null Black South Africans

por Naidoo, Kewreshini K., Ngubane, Ayanda, Gaza, Pedzisai, Moodley, Amber, Ndung'u, Thumbi, Thobakgale, Christina F.
Publicado 2019

Challenges of HIV diagnosis and management in the context of pre‐exposure prophylaxis (PrEP), post‐exposure prophylaxis (PEP), test and start and acute HIV infection: a scoping rev...

por Elliott, Tamara, Sanders, Eduard J, Doherty, Meg, Ndung'u, Thumbi, Cohen, Myron, Patel, Pragna, Cairns, Gus, Rutstein, Sarah E, Ananworanich, Jintanat, Brown, Colin, Fidler, Sarah
Publicado 2019

Rapid in-country sequencing of whole virus genomes to inform rabies elimination programmes

por Brunker, Kirstyn, Jaswant, Gurdeep, Thumbi, S.M., Lushasi, Kennedy, Lugelo, Ahmed, Czupryna, Anna M., Ade, Fred, Wambura, Gati, Chuchu, Veronicah, Steenson, Rachel, Ngeleja, Chanasa, Bautista, Criselda, Manalo, Daria L., Gomez, Ma. Ricci R., Chu, Maria Yna Joyce V., Miranda, Mary Elizabeth, Kamat, Maya, Rysava, Kristyna, Espineda, Jason, Silo, Eva Angelica V., Aringo, Ariane Mae, Bernales, Rona P., Adonay, Florencio F., Tildesley, Michael J., Marston, Denise A., Jennings, Daisy L., Fooks, Anthony R., Zhu, Wenlong, Meredith, Luke W., Hill, Sarah C., Poplawski, Radoslaw, Gifford, Robert J., Singer, Joshua B., Maturi, Mathew, Mwatondo, Athman, Biek, Roman, Hampson, Katie
Publicado 2020

Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection

por Kazer, Samuel W., Aicher, Toby P., Muema, Daniel M., Carroll, Shaina L., Ordovas-Montanes, Jose, Miao, Vincent N., Tu, Ang A., Ziegler, Carly G. K., Nyquist, Sarah K., Wong, Emily B., Ismail, Nasreen, Dong, Mary, Moodley, Amber, Berger, Bonnie, Love, J. Christopher, Dong, Krista L., Leslie, Alasdair, Ndhlovu, Zaza M., Ndung’u, Thumbi, Walker, Bruce D., Shalek, Alex K.
Publicado 2020

HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE

por Millar, Jane R., Bengu, Nomonde, Fillis, Rowena, Sprenger, Ken, Ntlantsana, Vuyokazi, Vieira, Vinicius A., Khambati, Nisreen, Archary, Moherndran, Muenchhoff, Maximilian, Groll, Andreas, Grayson, Nicholas, Adamson, John, Govender, Katya, Dong, Krista, Kiepiela, Photini, Walker, Bruce D., Bonsall, David, Connor, Thomas, Bull, Matthew J., Nxele, Nelisiwe, Roider, Julia, Ismail, Nasreen, Adland, Emily, Puertas, Maria C., Martinez-Picado, Javier, Matthews, Philippa C., Ndung'u, Thumbi, Goulder, Philip
Publicado 2020

African-led health research and capacity building- is it working?

por Kasprowicz, Victoria O., Chopera, Denis, Waddilove, Kim Darley, Brockman, Mark A., Gilmour, Jill, Hunter, Eric, Kilembe, William, Karita, Etienne, Gaseitsiwe, Simani, Sanders, Eduard J., Ndung’u, Thumbi
Publicado 2020

A longitudinal study of the association between domestic contact with livestock and contamination of household point-of-use stored drinking water in rural Siaya County (Kenya)

por Trajano Gomes da Silva, Diogo, Ebdon, James, Okotto-Okotto, Joseph, Ade, Frederick, Mito, Oscar, Wanza, Peggy, Kwoba, Emmah, Mwangi, Thumbi, Yu, Weiyu, Wright, Jim A.
Publicado 2020

An Assessment of Inter-Observer Agreement in Water Source Classification and Sanitary Risk Observations

por Okotto-Okotto, Joseph, Wanza, Peggy, Kwoba, Emmah, Yu, Weiyu, Dzodzomenyo, Mawuli, Thumbi, S. M., da Silva, Diogo Gomes, Wright, Jim A.
Publicado 2019

Pitfalls of Single Measurement Screening for Diabetes and Hypertension in Community-Based Settings

por Olivier, Stephen, Murray, Thomas, Matthews, Philippa, Mhlongo, Ngcebo, Gunda, Resign, Baisley, Kathy, Gareta, Dickman, Modise, Tshwaraganang, Smit, Theresa, Herbst, Kobus, Mpofana, Xolile, Ndung’u, Thumbi, Koole, Olivier, Pillay, Deenan, Hanekom, Willem, Wong, Emily, Siedner, Mark J.
Publicado 2021