“…Two studies were performed to determine the efficacy of ADS024 in a mouse model of CDI: Study 1 to determine the effects of fresh ADS024 culture and ADS024 spore preparations on the clinical manifestations of CDI in mice, and Study 2 to compare the efficacy of single daily doses vs dosing 3 times per day with fresh ADS024. C. difficile challenge was performed 24 h after the start of ADS024 exposure. …”
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“…HIV patients who received antiretroviral therapy had a 0.53 times higher risk of acquiring tuberculosis than HIV patients who did not receive antiretroviral therapy (AHR = 0.53; 95% CI: 0.3–0.77). …”
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“…Hypogonadism is another well-recognised cause and is primarily results from iron deposition in pituitary and at times in the gonads. Hormonal replacement therapy reduces bone loss. …”
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“…BACKGROUND: Timely and appropriate treatment for childhood illness saves the lives of millions of children. …”
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“…We assessed the percentage of patients reaching vitamin D adequacy (>30ng/ml) (VDA) by year and month of testing, by the use of VDS: in low dose (≤1200IU daily) (LD), medium dose (1201-3000IU daily) (MD) and high dose (>3000IU daily) (HD), by duration of use: short use (<12 months) and long term (≥12 months) (LT), by the timing of use: current use (CU), former use (stopped at least 2 months) (FU) and never use (NU). …”
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“…By easing diagnosis and monitoring of TBIR, the new assay for InsR-aAb quantification should enhance access to timely and effective treatment for TBIR. Presentation: Thursday, June 15, 2023…”
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“…Among the reasons respondents preferred somapacitan were: number of times needing to do injections (27/45; 60%); less worried about remembering to do injections (21/45; 46.7%); and child less worried about getting injections and child less annoyed about getting injections (both 15/45; 33.3%), as well as others. …”
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“…He was hospitalized frequently with upper respiratory tract infections and needed ICU care four times during the 5(th) year of his life. At age 5 years and 9 months and body weight of 89.9 kg (BMI SD:5.7), the compassionate use application to use Mibavademab was approved by the local ethics board and the Ministry of Health. …”
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“…Pharmacodynamic (PD) samples were taken at times 0-180 min, and glucose and insulin PD profiles determined. …”
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“…The study of Chinese medical history has mainly placed importance on the modern times. Indeed, no change has been present as well. …”
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“…The optimal desorption solvent was formic acid-methanol-water (0.5∶49.5∶50, v/v/v), and the optimal extraction and desorption times were 15 min. A method for the in vivo analysis of NTs in the brains of mice was established by combining the COF-SO(3)H fibers with ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) under optimal conditions. …”
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“…HBV burden in pregnancy, risk factors and the timing of mother to child transmission remain poorly described especially during this era of lifelong use of Tenofovir/Lamivudine/Efavirenz as firstline for HIV treatment. …”
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“…If CMT is not treated correctly and timely, it can lead to limited head and neck movements, head and neck deviation, and abnormal posture. …”
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“…Obtaining accurate and timely sexual health histories serve to identify risks of acquiring viral and bacterial communicable disease. …”
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“…A total of 100 patients with mild COVID-19 were enrolled from January through March 2022 during epidemic timing of omicron BA.1 strain. Patients were randomly assigned by allocation factors of age, anti-viral medication, and SARS-CoV-2 vaccine status in a 1:1 ratio to LC-Plasma group (oral LC- Plasma- capsule, 200 mg/day, for 14 days) or placebo (oral placebo capsule, for 14 days). …”
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“…METHODS: In this large retrospective US-based cohort study, RT-qPCR SARS-CoV-2 test data were linked to healthcare claims to calculate the viral rebound rate in treated and untreated individuals, among subjects tested at least 3 times during a SARS-CoV-2 infection. This cohort of 30,646 unique patients includes SARS-CoV-2 vaccinated patients, patients infected during the Omicron era, and high risk patients (those with underlying medical conditions associated with a higher risk for severe SARS-CoV-2 infection). …”
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“…Boxes indicate the horizontal line in each box represents the median, the top and bottom of the box the 25th and 75th percentiles, and the whiskers 1.5 times the interquartile range. (C and D) Classification of PNTM and PTB by Random Forest Model. …”
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“…He says: ‘Such findings suggest the development of a compensatory function on the part of the lymph-nodes and possibly the liver,’ and suggests that, in times of stress ‘the stellate cells of the liver thus assume, in part at least, the function of destroying red blood-corpuscles by phagocytosis.’ …”
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“…Conclusion: On the basis of their integrin α(v)β(3) binding affinity and tumor uptake of their corresponding (111)In radiotracers, it was conclude that 2P-RGD(4), 2P4G-RGD(4) and 6P-RGD(4) are most likely bivalent in binding to integrin α(v)β(3), and extra RGD motifs might contribute to the long tumor retention times of (111)In(DOTA-2P-RGD(4)),( 111)In(DOTA-2P4G-RGD(4)) and (111)In(DOTA-6P-RGD(4)) than that of (111)In(DOTA-3P-RGD(3)) at 72 h p.i. …”
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“…RESULTS: The mean age of onset in the two groups at Nationwide Children’s Hospital was 27 months and 91 months. The mean times between onset of symptoms to diagnosis in the younger and older age groups was 5.6 months and 4.5 months, respectively, not a statistically significant difference. …”
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