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  1. 2301
    “…A subset of 49 differentially expressed genes (DEGs) that were shared between the expression profiling results and the dysregulated pathways results were constructed into a co-expression network. The top 5 ranked DEGs, nuclear receptor subfamily 4 group A member 3 (NR4A3), JUNB proto-oncogene, MYC proto-oncogene, tachykinin precursor 1 and nicotinamide phosphoribosyltransferase, were identified as important in the topology analysis. …”
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    Personalized analysis of pathway aberrance induced by sevoflurane and propofol
  2. 2302
    “…The prognostic value of all miRNAs was analyzed by multivariate Cox regression, and the miRNAs were ranked according to the hazard ratio (HR) and P-values. The top 5 miRNAs (miR-1301, miR-125a, miR-376c, miR-328 and miR-376b) were significantly associated with OS (HR=0.139; 95% confidence interval, 0.043–0.443; P<0.001), thus demonstrating that this panel was able to serve as an independent prognostic factor for PAAD. …”
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    Prognostic microRNAs and their potential molecular mechanism in pancreatic cancer: A study based on The Cancer Genome Atlas and bioinformatics investigation
  3. 2303
    “…DESIGN: A cluster sampling study was performed to identify those residents who availed healthcare services and to assign them to HC (top 5%), moderate-cost (top 30%) and low-cost (others) groups based on their annual medical expenditures. …”
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    Medical expenditure clustering and determinants of the annual medical expenditures of residents: a population-based retrospective study from rural China
  4. 2304
    “…We also compared the sugar and energy content of top 5 CSSBs in terms of sales among three countries (China, UK and USA). …”
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    Sugar and energy content of carbonated sugar-sweetened beverages in Haidian District, Beijing: a cross-sectional study
  5. 2305
    “…Two hundred sixty-five patients had severe maternal diseases (maternal near miss), and the top 5 causes for severe maternal morbidity were massive blood transfusion, thrombocytopenia, clinical feature of shock, uterus removal induced by uterus infection or bleeding, and coagulation dysfunction, of which the morbidity were 24.15%, 18.87%, 13.58%, 9.43%, and 6.79%, respectively. …”
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    A retrospective cohort study of risk factors and pregnancy outcomes in 14,014 Chinese pregnant women
  6. 2306
    “…OBJECTIVE: To develop and validate the High Resource User Population Risk Tool (HRUPoRT), a predictive model of adults that will become the top 5% of health care users over a 5-year period, based on self-reported clinical, sociodemographic, and health behavioral predictors in population survey data. …”
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    Predicting High Health Care Resource Utilization in a Single-payer Public Health Care System: Development and Validation of the High Resource User Population Risk Tool
  7. 2307
    por Embrett, Mark, Randall, Glen E
    Publicado 2018
    “…Recently, Choosing Wisely campaigns began using ‘top 5 do-not-do’ lists to target unnecessary medical care by encouraging greater physician and patient dialogue at the point of care. …”
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    Physician perspectives on Choosing Wisely Canada as an approach to reduce unnecessary medical care: a qualitative study
  8. 2308
    “…The recommendation chosen for these top 5 groups were as follows: (1) Policy makers: Ensure universal access to PC; (2) Academia: Offer mandatory PC courses to undergraduates; (3) Healthcare workers: PC professionals should receive adequate certification; (4) Hospitals and healthcare centers: Every healthcare center should ensure access to PC medicines; and (5) PC associations: National Associations should be effective advocates and work with their governments in the process of implementing international policy framework. …”
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    White Paper for Global Palliative Care Advocacy: Recommendations from a PAL-LIFE Expert Advisory Group of the Pontifical Academy for Life, Vatican City
  9. 2309
    “…Importance of ranked top 15 was listed in descending order . The top 5 variables of great importance in MS prediction were TBIL difference between 2014 and 2015 (D_TBIL), TBIL in 2014 (TBIL 2014), LDL-C difference between 2014 and 2015 (D_LDL-C), CCMQ scores for balanced constitution in 2015 (balanced constitution 2015), and TCH in 2015 (TCH 2015). …”
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    Identification of Traditional Chinese Medicine Constitutions and Physiological Indexes Risk Factors in Metabolic Syndrome: A Data Mining Approach
  10. 2310
    “…Considering the vegetable market basket of Catalonia, an 8.2 m(2) soilless garden would be needed to cover 62% of the market basket for one person. The top 5 most productive crops were tomato, chard, lettuce, pepper and eggplant, accounting for 85.5% of the total production. …”
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    Agronomic and Environmental Assessment of a Polyculture Rooftop Soilless Urban Home Garden in a Mediterranean City
  11. 2311
    “…RESULTS: In comparison with SGC7901/S cells, SGC7901/DDP cells showed a total of 3165 DEGs (2014 upregulated and 1151 downregulated, fold change ≥2, and adjusted P value <0.001). qRT-PCR confirmed the reliability of the RNA sequencing results. Depletion of the top 5 upregulated mRNAs reversed the resistant index, increased apoptotic SGC7901/DDP cells, and arrested the cells at G2/M phase. …”
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    Next-Generation Sequencing Analysis of mRNA Profile in Cisplatin-Resistant Gastric Cancer Cell Line SGC7901
  12. 2312
    “…LSM, platelets, age, hyaluronic acid, and diameter of the spleen were the top 5 predictors associated with any stage of liver fibrosis and integrated into a novel noninvasive program, named as the Chin-CHB score. …”
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    A Novel Noninvasive Program for Staging Liver Fibrosis in Untreated Patients With Chronic Hepatitis B
  13. 2313
    “…These sites accounted for 75.45% (664/880) of results limited to the top 5 results. Repetitive short-term testing yielded similar results with minor changes in the rank order. …”
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    Clinician Job Searches in the Internet Era: Internet-Based Study
  14. 2314
    “…The national overall prevalence of HPV infection was 15.54% (95% CI: 13.83%‐17.24%). we also performed subgroup analysis by age, geographic location, level of economic development, HPV assay method, and type of HPV infection. The top 5 common HPV types detected in general population, were HPV 16 (3.52%, 95% CI: 3.18%‐3.86%), 52 (2.20%, 95% CI: 1.93%‐2.46%), 58 (2.10%, 95% CI: 1.88%‐2.32%), 18 (1.20%, 95% CI: 1.05%‐1.35%), and 33 (1.02%, 95% CI: 0.89%‐1.14%). …”
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    The prevalence, trends, and geographical distribution of human papillomavirus infection in China: The pooled analysis of 1.7 million women
  15. 2315
    “…ARM results showed a prominence of CKD in the most common top 5 combinations of conditions. Conclusion: Despite being younger than their HIV-free counterparts, PLwHIV with history of cancer carry a significantly greater comorbidity burden.…”
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    MULTIPLE CHRONIC CONDITIONS IN OLDER CANCER SURVIVORS WITH AND WITHOUT HIV
  16. 2316
    “…Sensitivity analyses were conducted using patients in the top 5% and top 20% of societal costs. Potential predictive factors included patient expectations, demographic factors (e.g. age, gender, nationality), socio‐economic factors (e.g. employment, education level) and health‐related factors (e.g. body mass index [BMI], general health, mental health). …”
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    Predictive factors of high societal costs among chronic low back pain patients
  17. 2317
    “…In the second round, the top 5 projects competed for reaching the final stage, in which the teams presented their ideas in front of a panel of international IPC experts to determine the first three ranks. …”
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    “Infection prevention and control idea challenge” contest: a fresh view on medical education and problem solving
  18. 2318
    “…Cardiovascular diseases, malignant neoplasms, digestive diseases, respiratory diseases, diabetes mellitus, and neurological conditions were the leading level 2 causes of ASDR due to NCD, while ischemic heart disease, stroke, other circulatory diseases, cirrhosis of the liver, and COPD were the top 5 causes of ASDR from NCD at level 3 causes. …”
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    The Burden of Noncommunicable Diseases in Ethiopia, 2000–2016: Analysis of Evidence from Global Burden of Disease Study 2016 and Global Health Estimates 2016
  19. 2319
    “…It was demonstrated that C-X-C motif chemokine ligand 8, elastase, neutrophil expressed, growth factor independent 1 transcriptional repressor, Spi-1 proto-oncogene, CCAAT enhancer binding protein epsilon, GATA binding protein 1, TAL bHLH transcription factor 1, erythroid differentiation factor, minichromosome maintenance complex component 4, BTG anti-proliferation factor 2, BRCA1 DNA repair-associated, cyclin D1, chromatin assembly factor 1 subunit A, triggering receptor expressed on myeloid cells 1 and tumor protein p63 were hub genes in the top 5 IPA networks (with a score >30). The present study provides insight into the pathological processes of FJOA from a genetic perspective and may thus benefit the clinical treatment of FJOA.…”
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    Ingenuity pathway analysis of human facet joint tissues: Insight into facet joint osteoarthritis
  20. 2320
    “…WNT5A promoted expression of 234 genes in human CD4(+) T cells, among which the Th2 cytokine IL31 was among the top 5 upregulated genes. IL31 was also upregulated in response to smooth muscle-specific WNT5A overexpression in the mouse. …”
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    Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation
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