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2321por Tao, Yan-gu, Huang, Xiu-Fang, Wang, Jun-yan, Kang, Meng-ru, Wang, Ling-jun, Xian, Shao-xiang“…STRING database was used to set up a protein-protein interaction network, and MCODE module and the top 5 targets with the highest degree for overlapping targets were obtained. …”
Publicado 2020
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2322por Cavallaro, Lucia, Ficara, Annamaria, De Meo, Pasquale, Fiumara, Giacomo, Catanese, Salvatore, Bagdasar, Ovidiu, Song, Wei, Liotta, Antonio“…For instance, when targeting the top 5% nodes with the largest Betweenness centrality, our simulations suggest a reduction of up to 70% in the size of the LCC. …”
Publicado 2020
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2323“…There were 69 unique anticipated SAEs identified, and 13 out of 69 were reported in at least 2 clinical trials. The top 5 anticipated SAEs for our study were: (1) hospitalization, psychiatric symptom (3.57%); (2) suicidal behavior, overdose (3.57%), (3) cholecystitis (2.86%); (4) fall (2.86%); (5) road traffic accident, injury (2.86%). …”
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2324por Wang, Zhen-Zhen, Jia, Yuan, Srivastava, Kamal D., Huang, Weihua, Tiwari, Raj, Nowak-Wegrzyn, Anna, Geliebter, Jan, Miao, Mingsan, Li, Xiu-Min“…We further identified top 5 compounds including cynarine, stigmasterin, kushenol, β-sitosterol, and (24S)-24-propylcholesta-5-ene-3β-ol as putative key active compounds on the basis of their molecular docking scores with identified hub target proteins. …”
Publicado 2021
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2325por Fisher, James, Card, Galen, Liang, Yuejin, Trent, Brandon, Rosenzweig, Holly, Soong, Lynn“…Mincle (Clec4e) was among the top 5 greatest up-regulated genes, accompanied with its signaling partners, type 1-skewing chemokines (Cxcr3, Ccr5, and their ligands), as well as Il27. …”
Publicado 2021
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2326por Stephenson, Ellen, Butt, Debra A., Gronsbell, Jessica, Ji, Catherine, O’Neill, Braden, Crampton, Noah, Tu, Karen“…Diabetes and hypertension remained among the top 5 reasons for visit during the pandemic, but there were 23.7% and 26.2% fewer visits and 19.5% and 28.8% fewer individual patients accessing care for diabetes and hypertension, respectively. …”
Publicado 2021
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2327por Yue, Taohua, Zuo, Shuai, Zhu, Jing, Guo, Shihao, Huang, Zhihao, Li, Jichang, Wang, Xin, Liu, Yucun, Chen, Shanwen, Wang, Pengyuan“…Both low macrophage abundance group and group D had higher TMB and PD-L1 expression. Furthermore, top 5 common gene-mutated STAD tissues had lower macrophage abundance. …”
Publicado 2021
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2328por Silva, Romina, Moran, Bruce, Baird, Anne-Marie, O’Rourke, Colm J., Finn, Stephen P., McDermott, Ray, Watson, William, Gallagher, William M., Brennan, Donal J., Perry, Antoinette S.“…After circulating cell-free DNA (cfDNA) isolation, DNA methylation was profiled using the Infinium MethylationEPIC BeadChip. The top 5% most variable probes across time, within each individual, were utilised to study dynamic methylation patterns during disease progression and therapeutic response. …”
Publicado 2021
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2329por Hammerman, Oded, Halperin, Daniel, Tsalihin, Daniel, Greenberg, Dan, Kushnir, Talma, Ezra, Yacov“…Electronic medical records were screened to identify the top 5% of FA. FA were stratified based on whether they had OI. …”
Publicado 2021
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2330“…Based on annual spending, we divided beneficiaries into 4 cost groups, representing the top 1%, top 5%, top 10% and the remaining 90%. We reported the following for each cost group: medication cost and proportion of total government spending, number of unique drugs dispensed per person and the top 10 most costly drug classes. …”
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2331por D’Souza, Rohan, Seymour, Rebecca J, Knight, Marian, Dzakpasu, Susie, Joseph, K S, Thorne, Sara, Ospina, Maria B, Barrett, Jon, Cook, Jocelynn, Fell, Deshayne B, Scott, Heather, Metcalfe, Amy, van den Akker, Thomas, Lapinsky, Stephen, Skeith, Leslie, Murray-Davis, Beth, Shah, Prakesh, Forte, Milena, Ashraf, Rizwana, Chundamala, Josie, Hutchinson, Sarah A, Chen, Kenneth K, Malhamé, Isabelle“…We will perform an integrated analysis to determine feasibility outcomes, a narrative description of barriers and facilitators for data-sharing and resource implications for data acquisition on an annual basis, and variations in top-5 causes of SMM. ETHICS AND DISSEMINATION: The study has been approved by the Mount Sinai and Hamilton Integrated Research Ethics Boards. …”
Publicado 2022
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2332por Xu, Anqi, Wen, Zhuo-Hua, Su, Shi-Xing, Chen, Yu-Peng, Liu, Wen-Chao, Guo, Shen-Quan, Li, Xi-Feng, Zhang, Xin, Li, Ran, Xu, Ning-Bo, Wang, Ke-Xin, Li, Wen-Xing, Guan, Dao-Gang, Duan, Chuan-Zhi“…By calculating the synergy score, we identified the top 5 candidate compounds. The experimental results showed that quercetin, baicalin, and ginsenoside Rg1 independently and synergistically increased cell viability. …”
Publicado 2022
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2333por Liu, Shixu, Cui, Xiangning, Xia, Kun, Wang, Dandan, Han, Jing, Yao, Xiaoyan, Liu, Xiaohong, Bian, Lingjie, Zhang, Jinzhi, Li, Guangxi“…American Journal of Physiology-Lung Cellular and Molecular Physiology was the journal with the most publications, and American Journal of Respiratory and Critical Care Medicine was the most commonly cited journal. All the top 5 co-cited journals belong to Q1. Keyword citation bursts revealed that inflammation, deficiency, tissue resident macrophage, classification, autoimmune pulmonary alveolar proteinosis, sarcoidosis, gm csf, high resolution ct, and fetal monocyte were the emerging research hotspots. …”
Publicado 2022
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2334por Xie, Hai, Jing, Ren, Liao, Xiaoting, Chen, Haishao, Xie, Xianlong, Dai, Huijun, Pan, Linghui“…CDK1, CCND1, RAF1, CDKN1B and BTRC were defined as the top 5 hub target genes, and patients with high expression of CDK1 showed poor prognosis. …”
Publicado 2022
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2335“…Of these, 85.3% (n = 5,375) ordered at least one microbiology test. The top 5 microbiology tests were blood culture, urine culture, respiratory polymerase chain reaction (PCR), urine antigen, and sputum culture. …”
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2336“…The research achievements of Japanese scholars in this field are of great significance. The top 5 ranked keywords are “Breast Cancer”, “Health-Related Quality Of Life”, “Lymphscintigraphy”, “Lymphovenous Anastomosis”, and “Lymphangiogenesis”. …”
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2337por Bi, Xiaojie, Zhang, Ying, Pan, Juan, Chen, Chaochao, Zheng, Yufen, Wang, Jing, Chen, Mengyuan, Zhou, Kai, Tung, Tao-Hsin, Shen, Bo, Wang, Donglian“…The white blood cell and neutrophil counts were lower in Omicron group than in the Fever group. The top 5 major symptoms were fever, cough, pharyngalgia, headache and expectoration. …”
Publicado 2022
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2338por Forssten, Maximilian Peter, Cao, Yang, Trivedi, Dhanisha Jayesh, Ekestubbe, Lovisa, Borg, Tomas, Bass, Gary Alan, Mohammad Ismail, Ahmad, Mohseni, Shahin“…Candidate variables were selected from the Nottingham Hip Fracture Score, Sernbo Score, Charlson Comorbidity Index, 5-factor modified Frailty Index, as well as the Revised Cardiac Risk Index and ranked based on their permutation importance, with the top 5 variables being selected for the score. The OFS was then validated on a local dataset that only included patients from Orebro County, Sweden. …”
Publicado 2022
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2339por Aghogho, Cynthia Idhigu, Eleblu, Saviour J. Y., Bakare, Moshood A., Kayondo, Ismail Siraj, Asante, Isaac, Parkes, Elizabeth Y., Kulakow, Peter, Offei, Samuel Kwame, Rabbi, Ismail“…Wrickle ecovalence (Wi) stability analysis and Geometric Adaptability index (GAI) identified G40 (TMS14F1285P0006) as part of top 5 genotypes for gari% but no overlapping genotype was identified by both stability analysis for fufu%. …”
Publicado 2022
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2340por Liu, Yunxia, Ye, Yun, Xie, Guanqun, Xu, Yefeng, Cheng, Miao, Li, Chunling, Qu, Mengqi, Zhu, Feiye“…One hundred and eighty-six putative targets were retrieved and bioinformatics analysis was performed to reveal the top 5 potential candidate agents and 10 core targets. …”
Publicado 2023
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