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441por Diharce, Julien, Cueto, Mickaël, Beltramo, Massimiliano, Aucagne, Vincent, Bonnet, Pascal“…Applied on a set of 11 crystallized peptide–protein complexes, the IRDL method shows promising results, since it is able to retrieve experimental binding conformations with a Root Mean Square Deviation (RMSD) below 2 Å in the top five ranked solutions. For some complexes, IRDL method outperforms two other docking protocols evaluated in this study. …”
Publicado 2019
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442por Gong, Li-Bao, Wen, Ti, Li, Zhi, Xin, Xing, Che, Xiao-Fang, Wang, Jin, Liu, Yun-Peng, Qu, Xiu-Juan“…Gastric cancer is one of the top five malignant tumors worldwide. At present, the molecular mechanisms of gastric cancer progression are still not completely clear. …”
Publicado 2019
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443por Phakeovilay, Chiobouaphong, Bourgeade-Delmas, Sandra, Perio, Pierre, Valentin, Alexis, Chassagne, François, Deharo, Eric, Reybier, Karine, Marti, Guillaume“…With an estimated annual incidence of one million cases, leishmaniasis is one of the top five vector-borne diseases. Currently available medical treatments involve side effects, including toxicity, non-specific targeting, and resistance development. …”
Publicado 2019
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444“…This study examines the impact of exchange rate volatility on Indonesia's primary export commodities to the top five export destination countries, namely China, India, Japan, South Korea, and the United States. …”
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445por Zhang, Qiujing, Wang, Jia, Liu, Menghan, Zhu, Qingqing, Li, Qiang, Xie, Chao, Han, Congcong, Wang, Yali, Gao, Min, Liu, Jie“…LASSO regression analysis of the top two gene modules identified ANGPT2, EMCN, GLDN, USHBP1 and ZNF532 as the top five mRNAsi-related genes. We constructed our survival model with these five genes and tested its performance using 243 HCC and 202 normal liver samples from the ICGC database. …”
Publicado 2020
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446por Korom, Philipp“…The careers of the most eminent economists are closely tied to the top five departments of the discipline, whereas the career pathways to eminence in sociology are largely unpredictable. …”
Publicado 2020
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447por Park, Seon-Cheol, Kim, Kiwon, Jang, Ok-Jin, Yoon, Hyung-Jun, Jang, Seung-Ho, Kim, Sung-Wan, Lee, Bong Ju, Park, Jae Hong, Lee, Kang Uk, Choi, Joonho“…Our results indicated that disclosure failure, excess syntactic constraints, abnormal prosody, and aprosodic speech rank among the top five central domains within the network structure. …”
Publicado 2020
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448“…Through the experiments, we discovered that the best feature set (including the top-five significant features) obtained the best classification performance. …”
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449por Saleh, Shadi, El Arnaout, Nour, Abdouni, Lina, Jammoul, Zeinab, Hachach, Noha, Dasgupta, Amlan“…Cloud-based electronic health records (EHRs) are considered among the top five health technologies integrated in humanitarian crisis preparedness and response during times of conflict. …”
Publicado 2020
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450por Yusoff, Siti Fairuz, Haron, Farah Farhanah, Tengku Muda Mohamed, Mahmud, Asib, Norhayu, Sakimin, Siti Zaharah, Abu Kassim, Faizah, Ismail, Siti Izera“…There were 23 chemical compounds identified in V. amygdalina dichloromethane extract using GCMS analysis. The top five major compounds were dominated by squalene (16.92%), phytol (15.05%), triacontane (11.31%), heptacosane (7.14%), and neophytadiene (6.28%). …”
Publicado 2020
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451por Eltoukhy, Abdelrahman E. E., Shaban, Ibrahim Abdelfadeel, Chan, Felix T. S., Abdel-Aal, Mohammad A. M.“…The viability and superiority of the developed algorithm are demonstrated by conducting experiments using data collected for top five affected countries in each continent. The results show an improved accuracy when compared with existing methods. …”
Publicado 2020
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452por Alshehri, Samah, Alshibani, Mohannad, Magboul, Ghaydaa, Albandar, Albandari, Nasser, Roaa, Yaqoub, Roaya M., Alzuhayri, Jumana, Aljabri, Ahmed“…A total of 684 (80.6%) patients were prescribed at least one medication listed in the first-class category of the 2019 Beers Criteria. Top five drugs were proton pump inhibitors (40.3%), nonsteroidal anti-inflammatory drugs (10.2%), metoclopramide (9.3%), benzodiazepines (8.4%), and insulin (5.4%). …”
Publicado 2020
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453por Lu, Xianju, Wang, Jinglu, Wang, Yongjian, Wen, Weiliang, Zhang, Ying, Du, Jianjun, Zhao, Yanxin, Guo, Xinyu“…A total of 224 genes annotated by SNPs at the top five of each GWAS method and detected by multiple GWAS methods were regarded as having high reliability. …”
Publicado 2021
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454“…The results are as follows: (1) The tourism economic ties of EU member states are growing increasingly close, enhancing network stability. (2) Germany, France, Italy, Austria and the United Kingdom are the top five countries in the degree centrality and closeness centrality rankings, meaning that they are located in the center of the network and have great influence, and the network is becoming increasingly concentrated. …”
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455“…A Modified Stacked Ensemble Learning (MSEL) is proposed in the second fold by stacking the top five pre-trained models, and then the predictions resulted. …”
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456“…Acute viral respiratory tract infections (AVRIs) are a major burden on human health and global economy and amongst the top five causes of death worldwide resulting in an estimated 3.9 million lives lost every year. …”
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457“…Participants with severe asthma (n=50) completed a cross-sectional survey that ranked 17 potential hypothetical outcomes of treatment using a seven-point Likert scale, as well as selecting their top five overall outcomes. Participants also completed hypothetical scenarios trading off medication characteristics for four hypothetical add-on asthma treatments. …”
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458por Liu, Zhaojun, Chen, Yang, Pan, Tingting, Liu, Jialin, Tian, Rui, Sun, Shaoqiong, Qu, Hongping, Chen, Erzhen“…Interestingly, four of the top five upregulated and all downregulated DEGs were involved in immune and inflammation signaling. …”
Publicado 2021
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459“…In-silico screening of EhPLK against small molecule libraries were performed and top five ranked molecules were shortlisted on the basis of docking scores. …”
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460por García-Montero, Cielo, Fraile-Martínez, Oscar, Bravo, Coral, Torres-Carranza, Diego, Sanchez-Trujillo, Lara, Gómez-Lahoz, Ana M., Guijarro, Luis G., García-Honduvilla, Natalio, Asúnsolo, Angel, Bujan, Julia, Monserrat, Jorge, Serrano, Encarnación, Álvarez-Mon, Melchor, De León-Luis, Juan A, Álvarez-Mon, Miguel A., Ortega, Miguel A.“…Moreover, we provide some updated points related to the landscape of the clinical development of vaccine candidates, specifically, the top five vaccines that are already being assessed in Phase IV clinical trials (BNT162b2, mRNA-1273, AZD1222, Ad26.COV2.S, and CoronaVac).…”
Publicado 2021
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