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  1. 1561
    “…RESULTS: Important risk predictors identified and ranked by the machine learning models were highly consistent: self-perceived health status factors always occupied the top five most important predictors, followed by worried about infection, working on the frontline, a very high level of uncertainty, having received any form of psychological support material and having COVID-19-like symptoms. …”
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    Machine Learning-Based Prediction Models for Depression Symptoms Among Chinese Healthcare Workers During the Early COVID-19 Outbreak in 2020: A Cross-Sectional Study
  2. 1562
    “…Significantly more participants (46.9%) were concerned about AstraZeneca thrombotic complications than other vaccine types. The top five side effects reported by participants were injection site pain (64.8%), sense of fatigue (57.1%), headache (49.9%), muscle pain (48.7%), and fever (46.5). …”
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    Perceptions and experiences of COVID-19 vaccines’ side effects among healthcare workers at an Egyptian University Hospital: a cross-sectional study
  3. 1563
    “…HPV58 (13.7%), HPV52 (11.7%), HPV53 (11.2%), HPV16 (10.0%), HPV18 (5.2%), and HPV51 (5.2%) were the top five high-risk HPV genotypes among women with cytological abnormalities. …”
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    Molecular Epidemiology of Human Papillomavirus Infection Among Chinese Women With Cervical Cytological Abnormalities
  4. 1564
    “…Ethnicity (OR = 2.93, 95% CI: 1.81–4.75; I(2) = 0), herdsman occupation (OR = 2.66, 95% CI: 2.25–3.14; I(2) = 8.0%), not washing hands before meals (OR = 2.40, 95% CI: 1.34–4.28; I(2) = 82.8%) and being female (OR = 1.45, 95% CI: 1.26–1.66; I(2) = 33.9%) were risk factors for AE. The top five risk factors for CE were ethnicity (OR = 3.18, 95% CI: 1.55–6.52; I(2) = 79.2%), nomadism (OR = 2.71, 95% CI: 1.65–4.47; I(2) = 55.8%), drinking nonboiled water (OR = 2.47, 95% CI: 1.36–4.47; I(2) = 85.7), feeding viscera to dogs (OR = 2.35, 95% CI: 1.89–2.91; I(2) = 21.5%), and herdsman occupation (OR = 2.19, 95% CI: 1.67–2.86; I(2) = 85.1%). …”
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    Risk Factors Associated With Echinococcosis in the General Chinese Population: A Meta-Analysis and Systematic Review
  5. 1565
    “…PPI network analysis identified Cxcr3, Il2ra, Il2rg, Lck, and Ccl5 as top five up-regulated genes showing highest interaction score, while Cyc1, Uqcrc1, Atp5d, Ndufa9, and Ndufs8 are down-regulated with highest scores. …”
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    Sex Differences in Diet-induced Obesity: Identification of Key Genes in Association With Phenotypes
  6. 1566
    “…We next examined mutational burdens and observed that the top five cancers were microsatellite stable (MSS) genotypes (mean TMB 49.3/Mb), while the other 16 MSS cancers had a mean TMB of 5.9/Mb. …”
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    Deep Sequencing of Early T Stage Colorectal Cancers Reveals Disruption of Homologous Recombination Repair in Microsatellite Stable Tumours with High Mutational Burdens
  7. 1567
    “…In particular, the sample of the present study consisted of 3,898 matches from the first and second divisions of the UEFA top five ranked countries, that is, England, Spain, Italy, Germany, and France. …”
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    A complete season with attendance restrictions confirms the relevant contribution of spectators to home advantage and referee bias in association football
  8. 1568
    “…Next, we mapped the RBPs that interact with the top five downregulated circRNAs (hsa_circ_0072309, circ_0004365, circ_0006677, circ_0008599, and circ_0009043) and hsa_circ_0000479, resulting in a total of 16 RBPs, most of them being enriched to pathways related to cancer and gene regulation (e.g., AGO1/2, EIF4A3, ELAVL1, and PTBP1). …”
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    Triple-Negative Breast Cancer circRNAome Reveals Hsa_circ_0072309 as a Potential Risk Biomarker
  9. 1569
    “…Patients with high risk scores also exhibited higher mRNA levels of immune checkpoints and lower IC50 values, indicating that these patients may be more prone to profit from chemotherapy and immunotherapy. The top five most abundant microbial phyla in ESCC was also identified. …”
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    Exploring the Potential of Exosome-Related LncRNA Pairs as Predictors for Immune Microenvironment, Survival Outcome, and Microbiotain Landscape in Esophageal Squamous Cell Carcinoma
  10. 1570
    “…In Nigeria ARB, CCB and diuretics were widely used; the top five products were 50 mg losartan, 10 mg lisinopril, 30 mg nifedipine, 40 mg furosemide, and 5 mg amlodipine. …”
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    Antihypertensive medicine use differs between Ghana and Nigeria
  11. 1571
    “…Results: A total of 23 Epimedium active ingredients, and 71 intersecting targets of Epimedium against vascular dementia were obtained. The top five hub targets AKT1, TNF, IL1β, IL6, and MMP9 were identified, and molecular docking showed good binding. …”
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    Molecular mechanism of Epimedium in the treatment of vascular dementia based on network pharmacology and molecular docking
  12. 1572
    “…In 620 patients, the result of the biochemical tests guided variant classification and reporting. Top five diagnosed diseases were: Gaucher disease, Niemann-Pick disease type A/B, phenylketonuria, mucopolysaccharidosis type I, and Wilson disease. …”
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    An integrated multiomic approach as an excellent tool for the diagnosis of metabolic diseases: our first 3720 patients
  13. 1573
    “…Then, 10 main clusters were generated with a modularity Q of 0.6442 and a weighted mean silhouette of 0.8325 by the log-likelihood ratio (LLR) algorithm, including #0 heart failure, #1 perfused heart, #2 metabolic disease, #3 protective effect, #4 diabetic patient, #5 cardiac fibrosis, #6 vascular complication, #7 mitochondrial dynamics, #8 sarcoplasmic reticulum, and #9 zinc supplementation. The top five references with the strongest citation bursts include “Boudina and Abel”, “Jia et al.”, “Fang et al.”, “Poornima et al.”, and “Aneja et al.”. …”
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    Knowledge domain and emerging trends in diabetic cardiomyopathy: A scientometric review based on CiteSpace analysis
  14. 1574
    “…We found relevant frequencies of individuals harboring these alterations: 222 heterozygotes (10.59%) for sequence variants, 54 heterozygotes (2.58%) for copy-number variants (CNV), and four homozygotes (0.19%) for sequence variants. The top five most frequent genes and their corresponding combined allelic frequencies (AF) were GJB2 (AF = 1.57%), STRC (AF = 1%), OTOA (AF = 0.69%), TMPRSS3 (AF = 0.41%), and OTOF (AF = 0.29%). …”
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    Genomic study of nonsyndromic hearing loss in unaffected individuals: Frequency of pathogenic and likely pathogenic variants in a Brazilian cohort of 2,097 genomes
  15. 1575
    “…Audience questions were categorized, with predominant topics as follows: Vaccine Safety, Medical Mistrust, Vaccine Safety in Pregnancy, Vaccine Efficacy, and Vaccine Development. The top five poll results revealed: 31% of audience members were not planning to vaccinate or were not sure about vaccination, but after the event are now planning to vaccinate; 93% believed their knowledge of the C19 vaccines had increased; 95% believed it was important that the information was presented by Black health experts; 90% reported that they trusted the information presented; and 96% rated the session as “good or excellent”. …”
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    Impact of a Black Physician Panel Discussion on Coronavirus Disease 2019 (COVID-19) Health Education
  16. 1576
    “…We ranked 2,740,314 paths in total between 35 Xanthium compounds and three diabetes-related phrases: type 1 diabetes, type 2 diabetes, and diabetes mellitus. Based on the top five percentile paths, we concluded that adenosine, choline, beta-sitosterol, rhamnose, and scopoletin were potential candidates for diabetes drug development using natural products. …”
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    An automatic hypothesis generation for plausible linkage between xanthium and diabetes
  17. 1577
    “…Besides, benzoquinone reductase, cellobiose dehydrogenase, glucose 1-oxidase, aryl alcohol oxidase and alcohol oxidase were the top five most abundant enzymes in the retting liquids. …”
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    Metagenomic and proteomic analysis of bacterial retting community and proteome profile in the degumming process of kenaf bast
  18. 1578
    “…In addition, further analysis of the top five pathways enriched by KEGG, nine key candidate genes (including SLC18A2, SNAP25, CACNA1B, GABRG2, DRD3, CAMK2A, NR5A1, and STAR) were identified, which could play a crucial role in the formation of semen. …”
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    Comparative Transcriptome Analysis Provided a New Insight into the Molecular Mechanisms of Epididymis Regulating Semen Volume in Drakes
  19. 1579
    “…In the USA, Salmonella enterica subspecies enterica serovar Senftenberg is among the top five serovars isolated from food and the top 11 serovars isolated from clinically ill animals. …”
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    Antimicrobial resistance and genomic characterization of Salmonella enterica serovar Senftenberg isolates in production animals from the United States
  20. 1580
    “…Over speeding, overloading, bad weather, vehicle failure, and driver error were the top five accident causes. CONCLUSION: Traffic accidents are increasing in high-altitude areas of western China, and they lead to more severe casualties. …”
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    Analysis on alteration of road traffic casualties in western China from multi-department data in recent decade
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