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  1. 2481
    “…METHODS: A retrospective review of patient charts and a functional investigation (involving Musculoskeletal Tumor Society Score [MSTS], American Knee Society Score [AKSS], Oxford Knee Score [OKS], Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC], Toronto Extremity Salvage Score [TESS], the 12-Item Short-Form [SF-12] Health Survey, and a failure classification system developed by Henderson et al.) of DFR cases from 2002 to 2015 were conducted. …”
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    Distal femoral replacement with the MML system: a single center experience with an average follow-up of 86 months
  2. 2482
    “…To assess the potential of genomics to address health needs in EMR, the World Health Organization's Eastern Mediterranean Regional Office and the University of Toronto Joint Centre for Bioethics jointly organized a Genomics and Public Health Policy Executive Course, held September 20(th)–23(rd), 2003, in Muscat, Oman. …”
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    Harnessing genomics to improve health in the Eastern Mediterranean Region – an executive course in genomics policy
  3. 2483
    “…We use this expanded set of reference core essential genes, CEG2, plus empirical data from six CRISPR knockout screens to guide the design of a sequence-optimized gRNA library, the Toronto KnockOut version 3.0 (TKOv3) library. We then demonstrate the high effectiveness of the library relative to reference sets of essential and nonessential genes, as well as other screens using similar approaches. …”
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    Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens
  4. 2484
    “…Images of radial artery were acquired bilaterally in the longitudinal view using a 50 MHz transducer (Vevo 2100 VisualSonics, Inc, Toronto, Ontario, Canada). Carotid IMT (cIMT) and rIMT were measured at <1 month after index PCI followed by a repeated measurement of rIMT at 4 months from the ACS in a sub-set (n=117). …”
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    Radial artery intima-media thickness regresses after secondary prevention interventions in patients’ post-acute coronary syndrome and is associated with cardiac and kidney biomarkers
  5. 2485
    “…METHODS: One thousand one hundred two women participating in the Toronto Nutrigenomics and Health Study provided data on their premenstrual symptoms and hormonal contraceptive use. …”
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    Hormonal contraceptive use and prevalence of premenstrual symptoms in a multiethnic Canadian population
  6. 2486
    “…ETHICS AND DISSEMINATION: The study has ethical approval from Kenyatta National Hospital/University of Nairobi Ethics and Research Committee, the University of Toronto Research Ethics Board and by Kenyan Pharmacy and Poisons Board. …”
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    Protocol of a randomised controlled trial characterising the immune responses induced by varicella-zoster virus (VZV) vaccination in healthy Kenyan women: setting the stage for a potential VZV-based HIV vaccine
  7. 2487
    “…We will recruit three primary care sites in Toronto, Ontario and three in Winnipeg, Manitoba that serve low-income communities. …”
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    Implementation and impact of an online tool used in primary care to improve access to financial benefits for patients: a study protocol
  8. 2488
    “…Comparisons using the Toronto Rehabilitation Institute Hand Function Test demonstrated no differences between groups in 7 of 9 domains. …”
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    Type and Timing of Rehabilitation Following Acute and Subacute Spinal Cord Injury: A Systematic Review
  9. 2489
    “…DSPN was defined by electrophysiological and clinical criteria (Toronto Consensus, 2011). SOD3 and GSH concentrations were lower in individuals with type 1 and type 2 diabetes compared with concentrations in controls (P<0.0001). …”
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    Lower serum extracellular superoxide dismutase levels are associated with polyneuropathy in recent-onset diabetes
  10. 2490
    “…The Barratt Impulsiveness Scale for Adolescent, the Snaith–Hamilton Pleasure Scale, the Dissociative Experience Scale for Adolescent, and the Toronto Alexithymia Scale were used to investigate psychopathological dimensions. …”
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    Gender Differences and Psychopathological Features Associated With Addictive Behaviors in Adolescents
  11. 2491
    “…SETTING: A multisite interdisciplinary primary care organisation in inner city Toronto, Canada, serving over 40 000 patients. PARTICIPANTS: The study population included 181 patients (53% female, mean age 48 years) who were referred to the Income Security Health Promotion service and engaged in care. …”
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    A novel income security intervention to address poverty in a primary care setting: a retrospective chart review
  12. 2492
    “…METHODS: Participants were 83 Internal Medicine and Pediatrics residents at the University of Toronto in 2014–15. The evaluation compared resource stewardship knowledge and communication skills of 57 (69%) residents that attended the resource stewardship workshop to 26 residents (31%) who did not. …”
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    Communicating wisely: teaching residents to communicate effectively with patients and caregivers about unnecessary tests
  13. 2493
    “…METHODS: This was a retrospective study of patients who underwent InterStim SNM at Toronto Western Hospital by 2 surgeons from July 2013 to March 2014. …”
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    Radiographic Position of the Electrode as a Predictor of the Outcome of InterStim Therapy
  14. 2494
    “…METHODS: Three descriptions of interventions tailored for LGBTQ+ YYA (group cessation counselling, social marketing, and a mobile phone app with social media incorporated), were shared with LGBTQ+ YYA via 24 focus groups with 204 participants in Toronto and Ottawa, Canada. Open-ended questions focused on their feelings, likes and dislikes, and concerns about the culturally modified intervention descriptions. …”
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    A qualitative study of tobacco interventions for LGBTQ+ youth and young adults: overarching themes and key learnings
  15. 2495
    “…To support this underserviced population, Toronto’s local health authority launched two novel community mental health models in 2014, inspired by Flexible Assertive Community Team principles. …”
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    Building flexibility and managing complexity in community mental health: lessons learned in a large urban centre
  16. 2496
    “…Given the complexities of leprosy management, a safety tool was developed and implemented in the Tropical Disease Unit at Toronto General Hospital. Our objective was to evaluate the utility of the tool using a retrospective chart review. …”
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    Evaluation of safety tool for ambulatory leprosy patients at risk of adverse outcome
  17. 2497
    “…OBJECTIVES: To evaluate the reliability of the newly developed consensus-based definition of TRM and explore the use of the cause-of-death attribution system outside the centre it was initially validated (Toronto, Canada). In the initial study, reviewers listed multiple causes of death. …”
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    Validation of a classification system for treatment-related mortality in children with cancer
  18. 2498
    “…MAIN TEXT: A seminar series on systems and complexity thinking hosted at the University of Toronto in 2016 offered a number of insights on applications of CAS perspectives to healthcare that we explore here. …”
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    Embracing uncertainty, managing complexity: applying complexity thinking principles to transformation efforts in healthcare systems
  19. 2499
    “…We prospectively collected Enterococcus faecium sterile site isolates from Toronto Invasive Bacterial Diseases Network hospitals from January 2015 to June 2016 and calculated VVE (defined as vanA-positive, vancomycin-susceptible isolates) prevalence among vanA-containing isolates. …”
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    Prevalence of vancomycin-variable Enterococcus faecium (VVE) among vanA-positive sterile site isolates and patient factors associated with VVE bacteremia
  20. 2500
    “…BACKGROUND: This article presents the results of a community consultation (CC) process completed in Toronto, Ontario, using a random digit dialling technique, on the attitudes and perceptions of the public toward the use of exception from informed consent when conducting emergency research involving the use of massive blood transfusions. …”
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    Protecting study participants in emergency research: is community consultation before trial commencement enough?
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