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  1. 261
    por Leiter, Lawrence A.
    Publicado 2020
    “…Presented at a recent symposium entitled “SUs in the treatment of T2DM: a fresh look and new insights” held on Wednesday September 18, 2019 during the 55th Annual Meeting of the European Association for the Study of Diabetes (EASD) in Barcelona Spain, this review discusses the initial evidence that sparked concerns over the CV safety of SUs as well as more recent findings from large studies of SUs (i.e. ADVANCE, TOSCA.IT and CAROLINA trials), highlighting the differences in CV and hypoglycaemia risks among the various SUs. …”
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    Latest Evidence on Sulfonylureas: What’s New?
  2. 262
    Publicado 1989
    Tabla de Contenidos: “…Dai campi, dai prati / Boíto (2:31) -- Tosca. Acte III. E lucevan le stelle / Puccini (2:37) -- Iris. …”
    CD Audiom
    Opera arias and songs
  3. 263
    Publicado 1993
    Tabla de Contenidos: “…/Cielo pietoso (5:33) / Verdi -- Tosca. Recondita armonia (2:47) ; E lucevan le stelle (3:08) / Puccini -- Luisa Miller. …”
    CD Audiom
    Ten top tenors
  4. 264
    “…Besides, Chinese TSC patients carried more TSC2 alterations (85.7% vs.76.2%, p<0.001), and were more likely to have a family history than those from TOSCA (22.2% vs. 13.9%, p<0.001). In conclusion, patients affected by bilateral renal AMLs should receive genetic testing of TSC ½ genes and Chinese TSC patients have relatively hotspot mutation regions, which are helpful to genetic counseling and clinical decision making.…”
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    Germline mutation of TSC1 or TSC2 gene in Chinese patients with bilateral renal angiomyolipomas and mutation spectrum of Chinese TSC patients
  5. 265
    por Khokhlova, O., Vinogradova, M.
    Publicado 2021
    “…Participants were given two standardized tests: Beck Depression Inventory and Test of Self-Conscious Affect (TOSCA) – 3. RESULTS: There were significant differences in levels of guilt between patients with personality disorders (M=64.79, SD=6.78) and healthy individuals (M = 59.92, SD = 11.86), t (102) = 2.603, p = .011. …”
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    Relationship between guilt and shame and depressive symptoms in normal population and patients with personality disorders
  6. 266
    Publicado 2007
    Conjunto
    Los clásicos de la ópera /
  7. 267
    “…RESULTS: We have compared the production of ethylene as well as the expression of 13 ethylene biosynthesis and signalling genes in pollinated and unpollinated ovaries/fruits of two cultivars, one of which is parthenocarpic (Cavili), while the other is non-parthenocarpic (Tosca). In the latter, unpollinated ovaries show an induction of ethylene biosynthesis and ethylene signal transduction pathway genes three days after anthesis, which is concomitant with the initiation of fruit abortion and senescence. …”
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    Involvement of ethylene biosynthesis and signalling in fruit set and early fruit development in zucchini squash (Cucurbita pepo L.)
  8. 268
    “…A remotely operated vehicle (ROV) was utilised during the TOSCA (Tectonic Ocean Spreading at the Charlie-Gibbs Fracture Zone) survey. …”
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    Benthic megafaunal biodiversity of the Charlie-Gibbs fracture zone: spatial variation, potential drivers, and conservation status
  9. 269
    “…Shame-proneness was assessed using the Test of the Self-Conscious Affect (TOSCA-3). RESULTS: Individuals with BPD experienced significantly higher levels of negative emotions than HCs both before and during the experimental task. …”
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    Shame, self-disgust, and envy: An experimental study on negative emotional response in borderline personality disorder during the confrontation with the own face
  10. 270
    “…METHODS: The Test of Self-Conscious Affect (TOSCA), which is the most used measure of shame-proneness, was completed by attempted suicide patients (n = 175: 105 women and 3 men with borderline personality disorder [BPD], 45 women and 22 men without BPD), non-suicidal psychiatric patients (n = 162), and healthy controls (n = 161). …”
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    Shame-proneness in attempted suicide patients
  11. 271
    “…MATERIALS AND METHODS: Venous blood gas sampling and monitoring of the PtCO(2) level (TCM TOSCA, Radiometer) were done simultaneously. All measurements are performed on mechanically ventilated infants. …”
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    Agreement of Mixed Venous Carbon Dioxide Tension (PvCO(2)) and Transcutaneous Carbon Dioxide (PtCO(2)) Measurements in Ventilated Infants
  12. 272
    “…Background: This study evaluated the characteristics of subependymal giant cell astrocytoma (SEGA) in patients with tuberous sclerosis complex (TSC) entered into the TuberOus SClerosis registry to increase disease Awareness (TOSCA). Methods: The study was conducted at 170 sites across 31 countries. …”
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    Clinical Characteristics of Subependymal Giant Cell Astrocytoma in Tuberous Sclerosis Complex
  13. 273
    “…The resulted parentage network suggested that the traditional Italian grapevine germplasm originates largely from a few central varieties geographically distributed into several areas of genetic influence: “Strinto porcino” and its offspring “Sangiovese”, “Mantonico bianco” and “Aglianico” mainly as founder varieties of South-Western Italy (IT-SW); Italian Adriatic Coast (IT-AC); and Central Italy with most varieties being offsprings of “Visparola”, “Garganega” and “Bombino bianco”; “Termarina (Sciaccarello)” “Orsolina” and “Uva Tosca” as the main varieties of North-Western Italy (IT-NW) and Central Italy. …”
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    Parentage Atlas of Italian Grapevine Varieties as Inferred From SNP Genotyping
  14. 274
    “…METHODS: Patients had completed 12 weeks of blinded treatment (placebo or ontamalimab at 22.5, 75, or 225 mg subcutaneously) in OPERA (NCT01276509) or had a clinical response to ontamalimab 225 mg in TOSCA (NCT01387594). Participants received ontamalimab at 75 mg every 4 weeks (weeks 0–72), then were followed up every 4 weeks for 24 weeks. …”
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    Long-Term Safety and Efficacy of the Anti-Mucosal Addressin Cell Adhesion Molecule-1 Monoclonal Antibody Ontamalimab (SHP647) for the Treatment of Crohn’s Disease: The OPERA II Study
  15. 275
    “…Students received structured video feedback according to one randomly assigned approach: checklist (CL), group (G), student tutor (ST), or teacher (T). Shame (ESS, TOSCA, subjective rating) and effectiveness (subjective ratings, remembered feedback points) were measured. …”
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    Face yourself! - learning progress and shame in different approaches of video feedback: a comparative study
  16. 276
    “…Polymorphisms contribute to inter-individual differences and show a promising predictive role for chemotherapy-related toxicity in colon cancer (CC). TOSCA is a multicentre, randomized, non-inferiority, phase III study conducted in high-risk stage II/stage III CC patients treated with 6 vs 3 months of FOLFOX-4 or XELOX adjuvant chemotherapy. …”
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    Sex-Related Differences in Impact on Safety of Pharmacogenetic Profile for Colon Cancer Patients Treated with FOLFOX-4 or XELOX Adjuvant Chemotherapy
  17. 277
    “…Hormonal deficiencies were defined according to T.O.S.C.A. multi-centric study, as previously published. …”
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    Anabolic Hormones Deficiencies in Heart Failure With Preserved Ejection Fraction: Prevalence and Impact on Antioxidants Levels and Myocardial Dysfunction
  18. 278
    “…The TuberOus SClerosis registry to increase disease Awareness (TOSCA) Post-Authorization Safety Study (PASS) was a non-interventional, multicenter, safety substudy that assessed the long-term safety of everolimus in patients with tuberous sclerosis complex (TSC) receiving everolimus for its licensed indications in the European Union (EU). …”
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    Real-World Evidence Study on the Long-Term Safety of Everolimus in Patients With Tuberous Sclerosis Complex: Final Analysis Results
  19. 279
    “…The yoke steel blocks, up to 620 mm thick, serve as the absorber plates of the muon detection system. A TOSCA 3-D model of the CMS magnet has been developed to describe the magnetic field outside of the solenoid volume, which was measured with a field-mapping machine. …”
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    Using the Standard Linear Ramps of the CMS Superconducting Magnet for Measuring the Magnetic Flux Density in the Steel Flux Return Yoke
  20. 280
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    Autorização para uso off-label pode ser benéfica para o Sistema Único de Saúde?
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