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121Specific Neuroligin3–αNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampuspor Uchigashima, Motokazu, Konno, Kohtarou, Demchak, Emily, Cheung, Amy, Watanabe, Takuya, Keener, David G, Abe, Manabu, Le, Timmy, Sakimura, Kenji, Sasaoka, Toshikuni, Uemura, Takeshi, Imamura Kawasawa, Yuka, Watanabe, Masahiko, Futai, Kensuke“…Here we demonstrate that Nlgn3 localizes at postsynaptic sites apposing vesicular glutamate transporter 3-expressing (VGT3+) inhibitory terminals and regulates VGT3+ inhibitory interneuron-mediated synaptic transmission in mouse organotypic slice cultures. …”
Publicado 2020
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122por Horackova, Hana, Karahoda, Rona, Cerveny, Lukas, Vachalova, Veronika, Ebner, Ronja, Abad, Cilia, Staud, Frantisek“…We hypothesize that antidepressants disturb serotonin homeostasis in the fetoplacental unit by inhibiting serotonin transporter (SERT) and organic cation transporter 3 (OCT3) in the maternal- and fetal-facing placental membranes, respectively. …”
Publicado 2021
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123“…In the present study, we used several markers of ACs, including gamma-aminobutyric acid (GABA), choline acetyltransferase (ChAT), neuropeptide Y (NPY), glycine transporter (GlyT1), and vesicular glutamate transporter 3 (VGlut3) to identify types of ACs that express Rbfox1. …”
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124“…This increase was also accompanied by a strong increase in glucose transporter 3 (Glut3), the major carrier responsible for glucose uptake in neurons. …”
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125por Aldahmash, Waleed, Harrath, Abdel Halim, Aljerian, Khaldoon, Sabr, Yasser, Alwasel, Saleh“…The goal of this study was to evaluate the expression of glucose transporter 1 (GLUT1) and glucose transporter 3 (GLUT3) in the placenta of women with gestational diabetes mellitus. …”
Publicado 2023
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126por Collins, Stuart A., Stinson, Hannah E., Himes, Amanda, Nestor-Kalinoski, Andrea, Ninan, Ipe“…We show that vesicular glutamate transporter 3 (VGLUT3)–expressing MRN neurons activate VGLUT3- and somatostatin-expressing neurons in the mPFC. …”
Publicado 2023
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127“…Here, we described a novel oligomerization mechanism affecting solute carrier family 30 member 3/zinc transporter 3 (SLC30A3/ZnT3). Oligomerization was mediated by intermolecular covalent dityrosine bonds. …”
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128por Ontawong, Atcharaporn, Saowakon, Naruwan, Vivithanaporn, Pornpun, Pongchaidecha, Anchalee, Lailerd, Narissara, Amornlerdpison, Doungporn, Lungkaphin, Anusorn, Srimaroeng, Chutima“…Renal cortical slices were used to determine renal transport of organic anions, which are estrone sulfate and para-aminohippurate, mediated through organic anion transporter 3-Oat3. Insulin and PKCζ were known to activate Oat3 function while it was inhibited by PKCα. …”
Publicado 2013
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129“…Post-mortem measures within the mPFC included glucose transporter 3 (GluT3) and c-Fos. RH animals had enhanced performance on day 1, consistent with previous work that showed RH to improve subsequent hippocampal function when euglycemic. …”
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130por Makinoshima, Hideki, Takita, Masahiro, Matsumoto, Shingo, Yagishita, Atsushi, Owada, Satoshi, Esumi, Hiroyasu, Tsuchihara, Katsuya“…On a molecular basis, the glucose transport carried out by glucose transporter 3 (GLUT3) was downregulated in TKI-sensitive LAD cells. …”
Publicado 2014
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131por Yisireyili, Maimaiti, Saito, Shinichi, Abudureyimu, Shaniya, Adelibieke, Yelixiati, Ng, Hwee-Yeong, Nishijima, Fuyuhiko, Takeshita, Kyosuke, Murohara, Toyoaki, Niwa, Toshimitsu“…Knock down of organic anion transporter 3 (OAT3), aryl hydrocarbon receptor (AhR) and nuclear factor-κB p65 (NF-κB p65) with small interfering RNAs inhibited IS-induced expression of PRR and prorenin in HASMCs. …”
Publicado 2014
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132por Liu, Jia-Wei, Si, Nuo, Wang, Lian-Qing, Shen, Ti, Zeng, Xue-Jun, Zhang, Xue, Ma, Dong-Lai“…The syndrome is caused by mutations in solute carrier family 29, member 3 (SLC29A3), the gene encoding equilibrative nucleoside transporter 3. The aim of this study was to identify pathogenic SLC29A3 mutations in a Chinese patient clinically diagnosed with H syndrome. …”
Publicado 2015
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133por Wang, Zhen Guang, Yu, Ming Ming, Han, Yu, Wu, Feng Yu, Yang, Guang Jie, Li, Da Cheng, Liu, Si Min“…The aim of the study was to investigate the correlation of glucose transporter-1 (Glut-1) and glucose transporter-3 (Glut-3) expression with F-18 FDG uptake in pulmonary inflammatory lesions. …”
Publicado 2016
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134“…Clock temporally regulates expression of organic cation transporter 3 (OCT3), which is involved in histamine transport, in mast cells; OCT inhibition abolished circadian variations in plasma histamine levels. …”
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135“…In CUMS-induced depression mice, there appear the decreases in the innervation and function of GABAergic axons and in the levels of mRNAs and proteins of glutamate decarboxylase-67, vesicular GABA transporter and GABA transporter-3. miRNA-15b-5p, miRNA-144-3p, miRNA-582-5p and miRNA-879-5p that directly downregulate such mRNAs increase in this cortex. …”
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136“…To confirm our previous study, we employed zinc transporter 3 (ZnT3) knockout mice to test whether vesicular zinc depletion shows protective effects on multiple sclerosis-induced white matter damage and motor deficits. …”
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137“…The effects of riluzole on these cells were associated with an inhibition of a poor prognostic indicator: glucose transporter 3 (GLUT3). A decrease in GLUT3 is associated with a decrease in the p-Akt/HIF1α pathway. …”
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138“…Finally, we identified tr–d events uniquely found in two extremophytes among the six Brassicaceae genomes, including tr–d of SALT TOLERANCE 32 and ZINC TRANSPORTER 3 that relate to their adaptive evolution. …”
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139“…Effects of inhibitors of the plasma membrane monoamine transporter (PMAT) and the organic cation transporter 3 (OCT3) (decynium‐22 and corticosterone) on the 5‐HT and 5‐HIAA concentrations during baseline, coronary occlusion, and reperfusion were investigated. …”
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140por Khomutov, Maxim, Hyvönen, Mervi T., Simonian, Alina, Formanovsky, Andrey A., Mikhura, Irina V., Chizhov, Alexander O., Kochetkov, Sergey N., Alhonen, Leena, Vepsäläinen, Jouko, Keinänen, Tuomo A., Khomutov, Alex R.“…The tested analogues overcame growth arrest induced by a 72 h treatment with α-difluoromethylornithine, an ornithine decarboxylase (ODC) inhibitor, and entered into DU145 cells via the polyamine transporter. 3,10-Me(2)Spm was a poor substrate of spermine oxidase and spermidine/spermine-N(1)-acetyltransferase (SSAT) when compared with 2,11-Me(2)Spm, thus resembling 1,12-dimethylspermine, which lacks the substrate properties required for the SSAT reaction. …”
Publicado 2019
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