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1por Prapa, Malvina, Chiavelli, Chiara, Golinelli, Giulia, Grisendi, Giulia, Bestagno, Marco, Di Tinco, Rosanna, Dall’Ora, Massimiliano, Neri, Giovanni, Candini, Olivia, Spano, Carlotta, Petrachi, Tiziana, Bertoni, Laura, Carnevale, Gianluca, Pugliese, Giuseppe, Depenni, Roberta, Feletti, Alberto, Iaccarino, Corrado, Pavesi, Giacomo, Dominici, Massimo“…Data highlighted a robust GD2 CAR antitumor potential in 2D and 3D glioblastoma models associated with a significant and CAR T-restricted increase of selected cytokines. …”
Publicado 2021
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2por Yi, Zhongzhen, Prinzing, Brooke L., Cao, Felicia, Gottschalk, Stephen, Krenciute, GiedreEnlace del recurso
Publicado 2018
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3por Golinelli, Giulia, Grisendi, Giulia, Dall'Ora, Massimiliano, Casari, Giulia, Spano, Carlotta, Talami, Rebecca, Banchelli, Federico, Prapa, Malvina, Chiavelli, Chiara, Rossignoli, Filippo, Candini, Olivia, D'Amico, Roberto, Nasi, Milena, Cossarizza, Andrea, Casarini, Livio, Dominici, MassimoEnlace del recurso
Publicado 2021
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6por Deshet-Unger, Naamit, Horn, Galit, Rawet-Slobodkin, Moran, Waks, Tova, Laskov, Ido, Michaan, Nadav, Raz, Yael, Bar, Vered, Zundelevich, Adi, Aharon, Sara, Turovsky, Lubov, Mallel, Giuseppe, Salpeter, Seth, Neev, Guy, Hollander, Kenneth Samuel, Katz, Ben-Zion, Grisaru, Dan, Globerson Levin, Anat“…We constructed a CAR that targets the ErbB2/HER2 protein (ErbB2CAR), which is overexpressed in HGSOC, and evaluated the functionality of ErbB2CAR on ovarian cancer cell lines (OVCAR8, SKOV3, and NAR). …”
Publicado 2022
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8por Zhang, Jue, Webster, Sarah, Duffin, Bret, Bernstein, Matthew N., Steill, John, Swanson, Scott, Forsberg, Matthew H., Bolin, Jennifer, Brown, Matthew E., Majumder, Aditi, Capitini, Christian M., Stewart, Ron, Thomson, James A., Slukvin, Igor I.“…Here, we used CRISPR-Cas9 gene editing methods to integrate an anti-GD2 CAR into the AAVS1 locus of human pluripotent stem cells (hPSCs). …”
Publicado 2023
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9por Zuo, Pengcheng, Li, Yaopeng, He, Chi, Wang, Tantan, Zheng, Xu, Liu, Hao, Wu, Zhen, Zhang, Junting, Liao, Xuebin, Zhang, Liwei“…Cell killing activity of GD2-CAR NK-92 cells was analyzed by in vitro cytotoxicity assays. …”
Publicado 2023
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10por Majzner, Robbie G., Ramakrishna, Sneha, Yeom, Kristen W., Patel, Shabnum, Chinnasamy, Harshini, Schultz, Liora M., Richards, Rebecca M., Jiang, Li, Barsan, Valentin, Mancusi, Rebecca, Geraghty, Anna C., Good, Zinaida, Mochizuki, Aaron Y., Gillespie, Shawn M., Toland, Angus Martin Shaw, Mahdi, Jasia, Reschke, Agnes, Nie, Esther H., Chau, Isabelle J., Rotiroti, Maria Caterina, Mount, Christopher W., Baggott, Christina, Mavroukakis, Sharon, Egeler, Emily, Moon, Jennifer, Erickson, Courtney, Green, Sean, Kunicki, Michael, Fujimoto, Michelle, Ehlinger, Zach, Reynolds, Warren, Kurra, Sreevidya, Warren, Katherine E., Prabhu, Snehit, Vogel, Hannes, Rasmussen, Lindsey, Cornell, Timothy T., Partap, Sonia, Fisher, Paul G., Campen, Cynthia J., Filbin, Mariella G., Grant, Gerald, Sahaf, Bita, Davis, Kara L., Feldman, Steven A., Mackall, Crystal L., Monje, Michelle“…Here we present the clinical experience from the first four patients with H3K27M-mutated DIPG or spinal cord DMG treated with GD2-CAR T cells at dose level 1 (1 × 10(6) GD2-CAR T cells per kg administered intravenously). …”
Publicado 2022
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11por Kase, Adam M., Kharfan‐Dabaja, Mohamed A., Donaldson, Andrew, Elliott, Jamie, Sher, Taimur“…We present a case of refractory follicular lymphoma who relapsed after two CAR‐T infusions and achieved a complete remission after treatment with obinutuzumab and lenalidomide. …”
Publicado 2022
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12From Anti-HER-2 to Anti-HER-2-CAR-T Cells: An Evolutionary Immunotherapy Approach for Gastric Cancer“…Here, we reviewed and discussed the current progress in the research of anti-HER-2-CAR-T cell immunotherapy against GC.…”
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13por Weng, Jianyu, Lai, Peilong, Qin, Le, Lai, Yunxin, Jiang, Zhiwu, Luo, Chenwei, Huang, Xin, Wu, Suijing, Shao, Dan, Deng, Chengxin, Huang, Lisi, Lu, Zesheng, Zhou, Maohua, Zeng, Lingji, Chen, Dongmei, Wang, Yulian, Chen, Xiaomei, Geng, Suxia, Robert, Weinkove, Tang, Zhaoyang, He, Chang, Li, Peng, Du, XinEnlace del recurso
Publicado 2018
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14por Hegde, Meenakshi, Joseph, Sujith K., Pashankar, Farzana, DeRenzo, Christopher, Sanber, Khaled, Navai, Shoba, Byrd, Tiara T., Hicks, John, Xu, Mina L., Gerken, Claudia, Kalra, Mamta, Robertson, Catherine, Zhang, Huimin, Shree, Ankita, Mehta, Birju, Dakhova, Olga, Salsman, Vita S., Grilley, Bambi, Gee, Adrian, Dotti, Gianpietro, Heslop, Helen E., Brenner, Malcolm K., Wels, Winfried S., Gottschalk, Stephen, Ahmed, Nabil“…Here we analyze the response of a child with refractory bone marrow metastatic rhabdomyosarcoma to autologous HER2 CAR T cells. Three cycles of HER2 CAR T cells given after lymphodepleting chemotherapy induces remission which is consolidated with four more CAR T-cell infusions without lymphodepletion. …”
Publicado 2020
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15por Tumino, Nicola, Weber, Gerrit, Besi, Francesca, Del Bufalo, Francesca, Bertaina, Valentina, Paci, Paola, Quatrini, Linda, Antonucci, Laura, Sinibaldi, Matilde, Quintarelli, Concetta, Maggi, Enrico, De Angelis, Biagio, Locatelli, Franco, Moretta, Lorenzo, Vacca, Paola, Caruana, Ignazio“…Moreover, in patients treated with GD2.CAR T-cells, the frequency of circulating PMN-MDSC inversely correlates with the levels of GD2.CAR T-cells, resulting more elevated in patients who did not respond or lost response to the treatment. …”
Publicado 2021
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16por Xia, Wenjiao, Chen, Jiaxin, Hou, Wenqing, Chen, Junsheng, Xiong, Ying, Li, Hongyan, Qi, Xin, Xu, Hui, Xie, Zuoquan, Li, Mingfeng, Zhang, Xiaomin, Li, Jing“…In vivo, sPD-1-CAR-NK cells had superior immunological anticancer efficacy compared to HER2-CAR-NK cells, and they had advantages over HER2-CAR-NK cells in the intraperitoneal injection of sPD-1. …”
Publicado 2023
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17por Heim, Catrin, Moser, Laura M., Kreyenberg, Herman, Bonig, Halvard B., Tonn, Torsten, Wels, Winfried S., Gradhand, Elise, Ullrich, Evelyn, Meister, Michael T., Koerkamp, Marian Groot, Holstege, Frank C. P., Drost, Jarno, Klusmann, Jan-Henning, Bader, Peter, Merker, Michael, Rettinger, EvaEnlace del recurso
Publicado 2023
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18por Mount, Christopher W., Majzner, Robbie G., Sundaresh, Shree, Arnold, Evan P., Kadapakkam, Meena, Haile, Samuel, Labanieh, Louai, Hulleman, Esther, Woo, Pamelyn J., Rietberg, Skyler P., Vogel, Hannes, Monje, Michelle, Mackall, Crystal L.Enlace del recurso
Publicado 2018
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19por Weng, Jianyu, Lai, Peilong, Qin, Le, Lai, Yunxin, Jiang, Zhiwu, Luo, Chenwei, Huang, Xin, Wu, Suijing, Shao, Dan, Deng, Chengxin, Huang, Lisi, Lu, Zesheng, Zhou, Maohua, Zeng, Lingji, Chen, Dongmei, Wang, Yulian, Chen, Xiaomei, Geng, Suxia, Weinkove, Robert, Tang, Zhaoyang, He, Chang, Li, Peng, Du, XinEnlace del recurso
Publicado 2019
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