The ferroportin Q248H mutation protects from anemia, but not malaria or bacteremia

por Muriuki, John Muthii, Mentzer, Alexander J., Band, Gavin, Gilchrist, James J., Carstensen, Tommy, Lule, Swaib A., Goheen, Morgan M., Joof, Fatou, Kimita, Wandia, Mogire, Reagan, Cutland, Clare L., Diarra, Amidou, Rautanen, Anna, Pomilla, Cristina, Gurdasani, Deepti, Rockett, Kirk, Mturi, Neema, Ndungu, Francis M., Scott, J. Anthony G., Sirima, Sodiomon B., Morovat, Alireza, Prentice, Andrew M., Madhi, Shabir A., Webb, Emily L., Elliott, Alison M., Bejon, Philip, Sandhu, Manjinder S., Hill, Adrian V. S., Kwiatkowski, Dominic P., Williams, Thomas N., Cerami, Carla, Atkinson, Sarah H.
Publicado 2019

Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models

por Manzari, Mandana T., Anderson, Grace R., Lin, Kevin H., Soderquist, Ryan S., Çakir, Merve, Zhang, Mitchell, Moore, Chandler E., Skelton, Rachel N., Fèvre, Maréva, Li, Xinghai, Bellucci, Joseph J., Wardell, Suzanne E., Costa, Simone A., Wood, Kris C., Chilkoti, Ashutosh
Publicado 2019

ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer

por Kuninty, Praneeth R., Bansal, Ruchi, De Geus, Susanna W. L., Mardhian, Deby F., Schnittert, Jonas, van Baarlen, Joop, Storm, Gert, Bijlsma, Maarten F., van Laarhoven, Hanneke W., Metselaar, Josbert M., Kuppen, Peter J. K., Vahrmeijer, Alexander L., Östman, Arne, Sier, Cornelis F. M., Prakash, Jai
Publicado 2019

Disruption of cardiac thin filament assembly arising from a mutation in LMOD2: A novel mechanism of neonatal dilated cardiomyopathy

por Ahrens-Nicklas, Rebecca C., Pappas, Christopher T., Farman, Gerrie P., Mayfield, Rachel M., Larrinaga, Tania M., Medne, Livija, Ritter, Alyssa, Krantz, Ian D., Murali, Chaya, Lin, Kimberly Y., Berger, Justin H., Yum, Sabrina W., Carreon, Chrystalle Katte, Gregorio, Carol C.
Publicado 2019

The Burden of Cerebrovascular Disease in the United States

por Tong, Xin, Yang, Quanhe, Ritchey, Matthew D., George, Mary G., Jackson, Sandra L., Gillespie, Cathleen, Merritt, Robert K.
Publicado 2019

Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit

por Qin, Bo, Humberg, Tim-Henning, Kim, Anna, Kim, Hyong S., Short, Jacob, Diao, Fengqiu, White, Benjamin H., Sprecher, Simon G., Yuan, Quan
Publicado 2019

Beyond duty hours: leveraging large-scale paging data to monitor resident workload

por Kaushal, Amit, Katznelson, Laurence, Harrington, Robert A.
Publicado 2019

Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity

por Heden, Timothy D., Johnson, Jordan M., Ferrara, Patrick J., Eshima, Hiroaki, Verkerke, Anthony R. P., Wentzler, Edward J., Siripoksup, Piyarat, Narowski, Tara M., Coleman, Chanel B., Lin, Chien-Te, Ryan, Terence E., Reidy, Paul T., de Castro Brás, Lisandra E., Karner, Courtney M., Burant, Charles F., Maschek, J. Alan, Cox, James E., Mashek, Douglas G., Kardon, Gabrielle, Boudina, Sihem, Zeczycki, Tonya N., Rutter, Jared, Shaikh, Saame Raza, Vance, Jean E., Drummond, Micah J., Neufer, P. Darrell, Funai, Katsuhiko
Publicado 2019

Unexpected fish diversity gradients in the Amazon basin

por Oberdorff, Thierry, Dias, Murilo S., Jézéquel, Céline, Albert, James S., Arantes, Caroline C., Bigorne, Rémy, Carvajal-Valleros, Fernando M., De Wever, Aaike, Frederico, R. G., Hidalgo, Max, Hugueny, Bernard, Leprieur, Fabien, Maldonado, Mabel, Maldonado-Ocampo, Javier, Martens, Koen, Ortega, Hernan, Sarmiento, Jaime, Tedesco, Pablo A., Torrente-Vilara, Gislene, Winemiller, Kirk O., Zuanon, Jansen
Publicado 2019

Clinical Identification and Referral of Adults With Prediabetes to a Diabetes Prevention Program

por Holliday, Christopher S., Williams, Janet, Salcedo, Vanessa, Kandula, Namratha R.
Publicado 2019

Albumin-chaperoned cyanine dye yields superbright NIR-II fluorophore with enhanced pharmacokinetics

por Tian, Rui, Zeng, Qiao, Zhu, Shoujun, Lau, Joseph, Chandra, Swati, Ertsey, Robert, Hettie, Kenneth S., Teraphongphom, Tarn, Hu, Zhubin, Niu, Gang, Kiesewetter, Dale O., Sun, Haitao, Zhang, Xiaodong, Antaris, Alexander L., Brooks, Bernard R., Chen, Xiaoyuan
Publicado 2019

Identification of Sialic Acid Linkages on Intact Glycopeptides via Differential Chemical Modification Using IntactGIG-HILIC

por Yang, Shuang, Wu, Wells W., Shen, Rong-Fong, Bern, Marshall, Cipollo, John
Publicado 2018

Generating keV ion distributions for nuclear reactions at near solid-density using intense short-pulse lasers

por Kemp, A. J., Wilks, S. C., Hartouni, E. P., Grim, G.
Publicado 2019

Layer 4 of mouse neocortex differs in cell types and circuit organization between sensory areas

por Scala, Federico, Kobak, Dmitry, Shan, Shen, Bernaerts, Yves, Laturnus, Sophie, Cadwell, Cathryn Rene, Hartmanis, Leonard, Froudarakis, Emmanouil, Castro, Jesus Ramon, Tan, Zheng Huan, Papadopoulos, Stelios, Patel, Saumil Surendra, Sandberg, Rickard, Berens, Philipp, Jiang, Xiaolong, Tolias, Andreas Savas
Publicado 2019

Development of R7BP inhibitors through cross-linking coupled mass spectrometry and integrated modeling

por Adikaram, Poorni R., Zhang, Jian-Hua, Kittock, Claire M., Pandey, Mritunjay, Hassan, Sergio A., Lue, Nicole G., Wang, Guanghui, Gucek, Marjan, Simonds, William F.
Publicado 2019

FRESH: Long-Term Outcomes of a Randomized Trial to Reduce Radon and Tobacco Smoke in the Home

por Hahn, Ellen J., Wiggins, Amanda T., Rademacher, Kathy, Butler, Karen M., Huntington-Moskos, Luz, Rayens, Mary Kay
Publicado 2019

SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors

por Yoshida, Akihiro, Bu, Yiwen, Qie, Shuo, Wrangle, John, Camp, E. Ramsay, Hazard, E. Starr, Hardiman, Gary, de Leeuw, Renée, Knudsen, Karen E., Diehl, J. Alan
Publicado 2019

BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers

por Kuznetsov, Jeffim N., Aguero, Tristan H., Owens, Dawn A., Kurtenbach, Stefan, Field, Matthew G., Durante, Michael A., Rodriguez, Daniel A., King, Mary Lou, Harbour, J. William
Publicado 2019

Small-molecule inhibitor targeting the Hsp90-Cdc37 protein-protein interaction in colorectal cancer

por Wang, Lei, Zhang, Lixiao, Li, Li, Jiang, Jingsheng, Zheng, Zhen, Shang, Jialin, Wang, Chengxiang, Chen, Weilin, Bao, Qichao, Xu, Xiaoli, Jiang, Zhengyu, Zhang, Jian, You, Qidong
Publicado 2019

Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection

por Khil, Pavel P., Dulanto Chiang, Augusto, Ho, Jonathan, Youn, Jung-Ho, Lemon, Jamie K., Gea-Banacloche, Juan, Frank, Karen M., Parta, Mark, Bonomo, Robert A., Dekker, John P.
Publicado 2019