Intracellular delivery of Parkin rescues neurons from accumulation of damaged mitochondria and pathological α-synuclein

por Chung, Eunna, Choi, Youngsil, Park, Jiae, Nah, Wonheum, Park, Jaehyung, Jung, Yukdong, Lee, Joonno, Lee, Hyunji, Park, Soyoung, Hwang, Sunyoung, Kim, Seongcheol, Lee, Jongseok, Min, Dongjae, Jo, Junghwan, Kang, Shinyoung, Jung, Minyong, Lee, Phil Hyu, Ruley, H. Earl, Jo, Daewoong
Publicado 2020

Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment

por Wang, Leiming, Cheng, Chiang-Min, Qin, Jun, Xu, Mafei, Kao, Chung-Yang, Shi, Jingjing, You, Erli, Gong, Wanchun, Rosa, Laura Pedro, Chase, Peter, Scampavia, Louis, Madoux, Franck, Spicer, Timothy, Hodder, Peter, Xu, H. Eric, Tsai, Sophia Y., Tsai, Ming-Jer
Publicado 2020

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity

por Fan, Zheng, Devlin, Jennifer R., Hogg, Simon J., Doyle, Maria A., Harrison, Paul F., Todorovski, Izabela, Cluse, Leonie A., Knight, Deborah A., Sandow, Jarrod J., Gregory, Gareth, Fox, Andrew, Beilharz, Traude H., Kwiatkowski, Nicholas, Scott, Nichollas E., Vidakovic, Ana Tufegdzic, Kelly, Gavin P., Svejstrup, Jesper Q., Geyer, Matthias, Gray, Nathanael S., Vervoort, Stephin J., Johnstone, Ricky W.
Publicado 2020

Nanovesicles derived from iron oxide nanoparticles–incorporated mesenchymal stem cells for cardiac repair

por Lee, Ju-Ro, Park, Bong-Woo, Kim, Jonghoon, Choo, Yeon Woong, Kim, Han Young, Yoon, Jeong-Kee, Kim, Hyeok, Hwang, Ji-Won, Kang, Mikyung, Kwon, Sung Pil, Song, Seuk Young, Ko, In Ok, Park, Ji-Ae, Ban, Kiwon, Hyeon, Taeghwan, Park, Hun-Jun, Kim, Byung-Soo
Publicado 2020

RasGRP1 is a causal factor in the development of l-DOPA–induced dyskinesia in Parkinson’s disease

por Eshraghi, Mehdi, Ramírez-Jarquín, Uri Nimrod, Shahani, Neelam, Nuzzo, Tommaso, De Rosa, Arianna, Swarnkar, Supriya, Galli, Nicole, Rivera, Oscar, Tsaprailis, George, Scharager-Tapia, Catherina, Crynen, Gogce, Li, Qin, Thiolat, Marie-Laure, Bezard, Erwan, Usiello, Alessandro, Subramaniam, Srinivasa
Publicado 2020

Augmentation of brain tumor interstitial flow via focused ultrasound promotes brain-penetrating nanoparticle dispersion and transfection

por Curley, Colleen T., Mead, Brian P., Negron, Karina, Kim, Namho, Garrison, William J., Miller, G. Wilson, Kingsmore, Kathryn M., Thim, E. Andrew, Song, Ji, Munson, Jennifer M., Klibanov, Alexander L., Suk, Jung Soo, Hanes, Justin, Price, Richard J.
Publicado 2020

Microbial predictors of healing and short-term effect of debridement on the microbiome of chronic wounds

por Verbanic, Samuel, Shen, Yuning, Lee, Juhee, Deacon, John M., Chen, Irene A.
Publicado 2020

Changes in contact patterns shape the dynamics of the COVID-19 outbreak in China

por Zhang, Juanjuan, Litvinova, Maria, Liang, Yuxia, Wang, Yan, Wang, Wei, Zhao, Shanlu, Wu, Qianhui, Merler, Stefano, Viboud, Cécile, Vespignani, Alessandro, Ajelli, Marco, Yu, Hongjie
Publicado 2020

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir

por Yin, Wanchao, Mao, Chunyou, Luan, Xiaodong, Shen, Dan-Dan, Shen, Qingya, Su, Haixia, Wang, Xiaoxi, Zhou, Fulai, Zhao, Wenfeng, Gao, Minqi, Chang, Shenghai, Xie, Yuan-Chao, Tian, Guanghui, Jiang, He-Wei, Tao, Sheng-Ce, Shen, Jingshan, Jiang, Yi, Jiang, Hualiang, Xu, Yechun, Zhang, Shuyang, Zhang, Yan, Xu, H. Eric
Publicado 2020

CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells

por Goodwin, M., Lee, E., Lakshmanan, U., Shipp, S., Froessl, L., Barzaghi, F., Passerini, L., Narula, M., Sheikali, A., Lee, C. M., Bao, G., Bauer, C. S., Miller, H. K., Garcia-Lloret, M., Butte, M. J., Bertaina, A., Shah, A., Pavel-Dinu, M., Hendel, A., Porteus, M., Roncarolo, M. G., Bacchetta, R.
Publicado 2020

Defined lifestyle and germline factors predispose Asian populations to gastric cancer

por Suzuki, Akihiro, Katoh, Hiroto, Komura, Daisuke, Kakiuchi, Miwako, Tagashira, Amane, Yamamoto, Shogo, Tatsuno, Kenji, Ueda, Hiroki, Nagae, Genta, Fukuda, Shiro, Umeda, Takayoshi, Totoki, Yasushi, Abe, Hiroyuki, Ushiku, Tetsuo, Matsuura, Tetsuya, Sakai, Eiji, Ohshima, Takashi, Nomura, Sachiyo, Seto, Yasuyuki, Shibata, Tatsuhiro, Rino, Yasushi, Nakajima, Atsushi, Fukayama, Masashi, Ishikawa, Shumpei, Aburatani, Hiroyuki
Publicado 2020

Structural basis for Ca(2+)-dependent activation of a plant metacaspase

por Zhu, Ping, Yu, Xiao-Hong, Wang, Cheng, Zhang, Qingfang, Liu, Wu, McSweeney, Sean, Shanklin, John, Lam, Eric, Liu, Qun
Publicado 2020

Trouble Sleeping and Depression Among US Women Aged 20 to 30 Years

por Barsha, Rifath Ara Alam, Hossain, Mian B.
Publicado 2020

Machine-learning-revealed statistics of the particle-carbon/binder detachment in lithium-ion battery cathodes

por Jiang, Zhisen, Li, Jizhou, Yang, Yang, Mu, Linqin, Wei, Chenxi, Yu, Xiqian, Pianetta, Piero, Zhao, Kejie, Cloetens, Peter, Lin, Feng, Liu, Yijin
Publicado 2020

Plasma proteomic signatures predict dementia and cognitive impairment

por Tanaka, Toshiko, Lavery, Robert, Varma, Vijay, Fantoni, Giovanna, Colpo, Marco, Thambisetty, Madhav, Candia, Julian, Resnick, Susan M., Bennett, David A., Biancotto, Angelique, Bandinelli, Stefania, Ferrucci, Luigi
Publicado 2020

A distinct class of plant and animal viral proteins that disrupt mitosis by directly interrupting the mitotic entry switch Wee1-Cdc25-Cdk1

por Jin, Huaibing, Du, Zhiqiang, Zhang, Yanjing, Antal, Judit, Xia, Zongliang, Wang, Yan, Gao, Yang, Zhao, Xiaoge, Han, Xinyun, Cheng, Yanjun, Shen, Qianhua, Zhang, Kunpu, Elder, Robert E., Benko, Zsigmond, Fenyvuesvolgyi, Csaba, Li, Ge, Rebello, Dionne, Li, Jing, Bao, Shilai, Zhao, Richard Y., Wang, Daowen
Publicado 2020

Competition between PAF1 and MLL1/COMPASS confers the opposing function of LEDGF/p75 in HIV latency and proviral reactivation

por Gao, Ru, Bao, Jiaqian, Yan, Han, Xie, Liya, Qin, Wanchang, Ning, Hanhan, Huang, Shuqi, Cheng, Jun, Zhi, Renyong, Li, Zexing, Tucker, Bronwyn, Chen, Yupeng, Zhang, Kai, Wu, Xudong, Liu, Zhe, Gao, Xin, Hu, Deqing
Publicado 2020

The obesity-induced adipokine sST2 exacerbates adipose T(reg) and ILC2 depletion and promotes insulin resistance

por Zhao, Xu-Yun, Zhou, Linkang, Chen, Zhimin, Ji, Yewei, Peng, Xiaoling, Qi, Ling, Li, Siming, Lin, Jiandie D.
Publicado 2020

Altered d-glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer’s disease detected by dynamic glucose-enhanced MRI

por Huang, Jianpan, van Zijl, Peter C. M., Han, Xiongqi, Dong, Celia M., Cheng, Gerald W. Y., Tse, Kai-Hei, Knutsson, Linda, Chen, Lin, Lai, Joseph H. C., Wu, Ed X., Xu, Jiadi, Chan, Kannie W. Y.
Publicado 2020

Characterization of the development of the mouse cochlear epithelium at the single cell level

por Kolla, Likhitha, Kelly, Michael C., Mann, Zoe F., Anaya-Rocha, Alejandro, Ellis, Kathryn, Lemons, Abigail, Palermo, Adam T., So, Kathy S., Mays, Joseph C., Orvis, Joshua, Burns, Joseph C., Hertzano, Ronna, Driver, Elizabeth C., Kelley, Matthew W.
Publicado 2020