Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail

por Zhang, Yuxia, Inoue, Michio, Tsutsumi, Akihisa, Watanabe, Satoshi, Nishizawa, Tomohiro, Nagata, Kazuhiro, Kikkawa, Masahide, Inaba, Kenji
Publicado 2020

Artificially induced MAIT cells inhibit M. bovis BCG but not M. tuberculosis during in vivo pulmonary infection

por Yu, Huifeng, Yang, Amy, Derrick, Steven, Mak, Jeffrey Y. W., Liu, Ligong, Fairlie, David P., Cowley, Siobhan
Publicado 2020

Tubulin islands containing slowly hydrolyzable GTP analogs regulate the mechanism and kinetics of microtubule depolymerization

por Bollinger, Jonathan A., Imam, Zachary I., Stevens, Mark J., Bachand, George D.
Publicado 2020

Deep neural networks enable quantitative movement analysis using single-camera videos

por Kidziński, Łukasz, Yang, Bryan, Hicks, Jennifer L., Rajagopal, Apoorva, Delp, Scott L., Schwartz, Michael H.
Publicado 2020

Single-trial cross-area neural population dynamics during long-term skill learning

por Veuthey, T. L., Derosier, K., Kondapavulur, S., Ganguly, K.
Publicado 2020

Self-targeting, zwitterionic micellar dispersants enhance antibiotic killing of infectious biofilms—An intravital imaging study in mice

por Tian, Shuang, Su, Linzhu, Liu, Yong, Cao, Jingjing, Yang, Guang, Ren, Yijin, Huang, Fan, Liu, Jianfeng, An, Yingli, van der Mei, Henny C., Busscher, Henk J., Shi, Linqi
Publicado 2020

Altered 3D chromatin structure permits inversional recombination at the IgH locus

por Qiu, Xiang, Ma, Fei, Zhao, Mingming, Cao, Yaqiang, Shipp, Lillian, Liu, Angela, Dutta, Arun, Singh, Amit, Braikia, Fatima Zohra, De, Supriyo, Wood, William H., Becker, Kevin G., Zhou, Weiqiang, Ji, Hongkai, Zhao, Keji, Atchison, Michael L., Sen, Ranjan
Publicado 2020

Near–atomic-scale observation of grain boundaries in a layer-stacked two-dimensional polymer

por Qi, Haoyuan, Sahabudeen, Hafeesudeen, Liang, Baokun, Položij, Miroslav, Addicoat, Matthew A., Gorelik, Tatiana E., Hambsch, Mike, Mundszinger, Manuel, Park, SangWook, Lotsch, Bettina V., Mannsfeld, Stefan C. B., Zheng, Zhikun, Dong, Renhao, Heine, Thomas, Feng, Xinliang, Kaiser, Ute
Publicado 2020

Wound healing after excision of subcutaneous tumors treated with near‐infrared photoimmunotherapy

por Rosenberg, Adrian, Inagaki, Fuyuki, Kato, Takuya, Okada, Ryuhei, Wakiyama, Hiroaki, Furusawa, Aki, Choyke, Peter L., Kobayashi, Hisataka
Publicado 2020

Interaction of the pioneer transcription factor GATA3 with nucleosomes

por Tanaka, Hiroki, Takizawa, Yoshimasa, Takaku, Motoki, Kato, Daiki, Kumagawa, Yusuke, Grimm, Sara A., Wade, Paul A., Kurumizaka, Hitoshi
Publicado 2020

Multimodal soft tissue markers for bridging high-resolution diagnostic imaging with therapeutic intervention

por Hansen, Anders E., Henriksen, Jonas R., Jølck, Rasmus I., Fliedner, Frederikke P., Bruun, Linda M., Scherman, Jonas, Jensen, Andreas I., Munck af Rosenschöld, Per., Moorman, Lilah, Kurbegovic, Sorel, de Blanck, Steen R., Larsen, Klaus R., Clementsen, Paul F., Christensen, Anders N., Clausen, Mads H., Wang, Wenbo, Kempen, Paul, Christensen, Merete, Viby, Niels-Erik, Persson, Gitte, Larsen, Rasmus, Conradsen, Knut, McEvoy, Fintan J., Kjaer, Andreas, Eriksen, Thomas, Andresen, Thomas L.
Publicado 2020

A gene therapy for inherited blindness using dCas9-VPR–mediated transcriptional activation

por Böhm, Sybille, Splith, Victoria, Riedmayr, Lisa Maria, Rötzer, René Dominik, Gasparoni, Gilles, Nordström, Karl J. V., Wagner, Johanna Elisabeth, Hinrichsmeyer, Klara Sonnie, Walter, Jörn, Wahl-Schott, Christian, Fenske, Stefanie, Biel, Martin, Michalakis, Stylianos, Becirovic, Elvir
Publicado 2020

Interferon-γ signaling in human iPSC–derived neurons recapitulates neurodevelopmental disorder phenotypes

por Warre-Cornish, Katherine, Perfect, Leo, Nagy, Roland, Duarte, Rodrigo R. R., Reid, Matthew J., Raval, Pooja, Mueller, Annett, Evans, Amanda L., Couch, Amalie, Ghevaert, Cédric, McAlonan, Grainne, Loth, Eva, Murphy, Declan, Powell, Timothy R., Vernon, Anthony C., Srivastava, Deepak P., Price, Jack
Publicado 2020

Reengineering biocatalysts: Computational redesign of chondroitinase ABC improves efficacy and stability

por Hettiaratchi, Marian H., O’Meara, Matthew J., O’Meara, Teresa R., Pickering, Andrew J., Letko-Khait, Nitzan, Shoichet, Molly S.
Publicado 2020

Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer’s disease mouse model

por Chen, Chun, Ahn, Eun Hee, Kang, Seong Su, Liu, Xia, Alam, Ashfaqul, Ye, Keqiang
Publicado 2020

Accessing new magnetic regimes by tuning the ligand spin-orbit coupling in van der Waals magnets

por Tartaglia, Thomas A., Tang, Joseph N., Lado, Jose L., Bahrami, Faranak, Abramchuk, Mykola, McCandless, Gregory T., Doyle, Meaghan C., Burch, Kenneth S., Ran, Ying, Chan, Julia Y., Tafti, Fazel
Publicado 2020

Peptidoglycan editing provides immunity to Acinetobacter baumannii during bacterial warfare

por Le, Nguyen-Hung, Peters, Katharina, Espaillat, Akbar, Sheldon, Jessica R., Gray, Joe, Di Venanzio, Gisela, Lopez, Juvenal, Djahanschiri, Bardya, Mueller, Elizabeth A., Hennon, Seth W., Levin, Petra Anne, Ebersberger, Ingo, Skaar, Eric P., Cava, Felipe, Vollmer, Waldemar, Feldman, Mario F.
Publicado 2020

Molecular and functional architecture of the mouse photoreceptor network

por Jin, Nange, Zhang, Zhijing, Keung, Joyce, Youn, Sean B., Ishibashi, Munenori, Tian, Lian-Ming, Marshak, David W., Solessio, Eduardo, Umino, Yumiko, Fahrenfort, Iris, Kiyama, Takae, Mao, Chai-An, You, Yanan, Wei, Haichao, Wu, Jiaqian, Postma, Friso, Paul, David L., Massey, Stephen C., Ribelayga, Christophe P.
Publicado 2020

Detection of response to tumor microenvironment–targeted cellular immunotherapy using nano-radiomics

por Devkota, Laxman, Starosolski, Zbigniew, Rivas, Charlotte H., Stupin, Igor, Annapragada, Ananth, Ghaghada, Ketan B., Parihar, Robin
Publicado 2020

TIP60 K430 SUMOylation attenuates its interaction with DNA-PKcs in S-phase cells: Facilitating homologous recombination and emerging target for cancer therapy

por Gao, Shan-Shan, Guan, Hua, Yan, Shuang, Hu, Sai, Song, Man, Guo, Zong-Pei, Xie, Da-Fei, Liu, Yike, Liu, Xiaodan, Zhang, Shimeng, Zhou, Ping-Kun
Publicado 2020