LSD1 enzyme inhibitor TAK-418 unlocks aberrant epigenetic machinery and improves autism symptoms in neurodevelopmental disorder models

por Baba, Rina, Matsuda, Satoru, Arakawa, Yuuichi, Yamada, Ryuji, Suzuki, Noriko, Ando, Tatsuya, Oki, Hideyuki, Igaki, Shigeru, Daini, Masaki, Hattori, Yasushi, Matsumoto, Shigemitsu, Ito, Mitsuhiro, Nakatani, Atsushi, Kimura, Haruhide
Publicado 2021

M-CSF, IL-6, and TGF-β promote generation of a new subset of tissue repair macrophage for traumatic brain injury recovery

por Li, Zhiqi, Xiao, Jun, Xu, Xiaoyan, Li, Weiyun, Zhong, Ruiyue, Qi, Linlin, Chen, Jiehui, Cui, Guizhong, Wang, Shuang, Zheng, Yuxiao, Qiu, Ying, Li, Sheng, Zhou, Xin, Lu, Yao, Lyu, Jiaying, Zhou, Bin, Zhou, Jiawei, Jing, Naihe, Wei, Bin, Hu, Jin, Wang, Hongyan
Publicado 2021

Atoh7-independent specification of retinal ganglion cell identity

por Brodie-Kommit, Justin, Clark, Brian S., Shi, Qing, Shiau, Fion, Kim, Dong Won, Langel, Jennifer, Sheely, Catherine, Ruzycki, Philip A, Fries, Michel, Javed, Awais, Cayouette, Michel, Schmidt, Tiffany, Badea, Tudor, Glaser, Tom, Zhao, Haiqing, Singer, Joshua, Blackshaw, Seth, Hattar, Samer
Publicado 2021

Injury-mediated stiffening persistently activates muscle stem cells through YAP and TAZ mechanotransduction

por Silver, Jason S., Günay, K. Arda, Cutler, Alicia A., Vogler, Thomas O., Brown, Tobin E., Pawlikowski, Bradley T., Bednarski, Olivia J., Bannister, Kendra L., Rogowski, Cameron J., Mckay, Austin G., DelRio, Frank W., Olwin, Bradley B., Anseth, Kristi S.
Publicado 2021

Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A

por White, Kris M., Rosales, Romel, Yildiz, Soner, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Jangra, Sonia, Uccellini, Melissa B., Rathnasinghe, Raveen, Coughlan, Lynda, Martinez-Romero, Carles, Batra, Jyoti, Rojc, Ajda, Bouhaddou, Mehdi, Fabius, Jacqueline M., Obernier, Kirsten, Dejosez, Marion, Guillén, María José, Losada, Alejandro, Avilés, Pablo, Schotsaert, Michael, Zwaka, Thomas, Vignuzzi, Marco, Shokat, Kevan M., Krogan, Nevan J., García-Sastre, Adolfo
Publicado 2021

Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody

por Rappazzo, C. Garrett, Tse, Longping V., Kaku, Chengzi I., Wrapp, Daniel, Sakharkar, Mrunal, Huang, Deli, Deveau, Laura M., Yockachonis, Thomas J., Herbert, Andrew S., Battles, Michael B., O’Brien, Cecilia M., Brown, Michael E., Geoghegan, James C., Belk, Jonathan, Peng, Linghang, Yang, Linlin, Hou, Yixuan, Scobey, Trevor D., Burton, Dennis R., Nemazee, David, Dye, John M., Voss, James E., Gunn, Bronwyn M., McLellan, Jason S., Baric, Ralph S., Gralinski, Lisa E., Walker, Laura M.
Publicado 2021

Seasonal overturn and stratification changes drive deep-water warming in one of Earth’s largest lakes

por Anderson, Eric J., Stow, Craig A., Gronewold, Andrew D., Mason, Lacey A., McCormick, Michael J., Qian, Song S., Ruberg, Steven A., Beadle, Kyle, Constant, Stephen A., Hawley, Nathan
Publicado 2021

Catalytic amplification by transition-state molecular switches for direct and sensitive detection of SARS-CoV-2

por Sundah, Noah R., Natalia, Auginia, Liu, Yu, Ho, Nicholas R. Y., Zhao, Haitao, Chen, Yuan, Miow, Qing Hao, Wang, Yu, Beh, Darius L. L., Chew, Ka Lip, Chan, Douglas, Tambyah, Paul A., Ong, Catherine W. M., Shao, Huilin
Publicado 2021

A towering genome: Experimentally validated adaptations to high blood pressure and extreme stature in the giraffe

por Liu, Chang, Gao, Jianbo, Cui, Xinxin, Li, Zhipeng, Chen, Lei, Yuan, Yuan, Zhang, Yaolei, Mei, Liangwei, Zhao, Lan, Cai, Dan, Hu, Mingliang, Zhou, Botong, Li, Zihe, Qin, Tao, Si, Huazhe, Li, Guangyu, Lin, Zeshan, Xu, Yicheng, Zhu, Chenglong, Yin, Yuan, Zhang, Chenzhou, Xu, Wenjie, Li, Qingjie, Wang, Kun, Gilbert, M. Thomas P., Heller, Rasmus, Wang, Wen, Huang, Jinghui, Qiu, Qiang
Publicado 2021

Strongly correlated superconductivity in a copper-based metal-organic framework with a perfect kagome lattice

por Takenaka, T., Ishihara, K., Roppongi, M., Miao, Y., Mizukami, Y., Makita, T., Tsurumi, J., Watanabe, S., Takeya, J., Yamashita, M., Torizuka, K., Uwatoko, Y., Sasaki, T., Huang, X., Xu, W., Zhu, D., Su, N., Cheng, J.-G., Shibauchi, T., Hashimoto, K.
Publicado 2021

Serial femtosecond and serial synchrotron crystallography can yield data of equivalent quality: A systematic comparison

por Mehrabi, P., Bücker, R., Bourenkov, G., Ginn, H.M., von Stetten, D., Müller-Werkmeister, H.M., Kuo, A., Morizumi, T., Eger, B.T., Ou, W.-L., Oghbaey, S., Sarracini, A., Besaw, J.E., Pare´-Labrosse, O., Meier, S., Schikora, H., Tellkamp, F., Marx, A., Sherrell, D.A., Axford, D., Owen, R.L., Ernst, O.P., Pai, E.F., Schulz, E.C., Miller, R.J.D.
Publicado 2021

Low ABA concentration promotes root growth and hydrotropism through relief of ABA INSENSITIVE 1-mediated inhibition of plasma membrane H(+)-ATPase 2

por Miao, Rui, Yuan, Wei, Wang, Yue, Garcia-Maquilon, Irene, Dang, Xiaolin, Li, Ying, Zhang, Jianhua, Zhu, Yiyong, Rodriguez, Pedro L., Xu, Weifeng
Publicado 2021

Three-dimensional, multifunctional neural interfaces for cortical spheroids and engineered assembloids

por Park, Yoonseok, Franz, Colin K., Ryu, Hanjun, Luan, Haiwen, Cotton, Kristen Y., Kim, Jong Uk, Chung, Ted S., Zhao, Shiwei, Vazquez-Guardado, Abraham, Yang, Da Som, Li, Kan, Avila, Raudel, Phillips, Jack K., Quezada, Maria J., Jang, Hokyung, Kwak, Sung Soo, Won, Sang Min, Kwon, Kyeongha, Jeong, Hyoyoung, Bandodkar, Amay J., Han, Mengdi, Zhao, Hangbo, Osher, Gabrielle R., Wang, Heling, Lee, KunHyuck, Zhang, Yihui, Huang, Yonggang, Finan, John D., Rogers, John A.
Publicado 2021

Ultrafast multi-cycle terahertz measurements of the electrical conductivity in strongly excited solids

por Chen, Z., Curry, C. B., Zhang, R., Treffert, F., Stojanovic, N., Toleikis, S., Pan, R., Gauthier, M., Zapolnova, E., Seipp, L. E., Weinmann, A., Mo, M. Z., Kim, J. B., Witte, B. B. L., Bajt, S., Usenko, S., Soufli, R., Pardini, T., Hau-Riege, S., Burcklen, C., Schein, J., Redmer, R., Tsui, Y. Y., Ofori-Okai, B. K., Glenzer, S. H.
Publicado 2021

Surface localized magnetism in transition metal doped alumina

por Nykwest, Erik C., Trujillo, Dennis, Alpay, S. Pamir
Publicado 2021

In situ microbeam surface X-ray scattering reveals alternating step kinetics during crystal growth

por Ju, Guangxu, Xu, Dongwei, Thompson, Carol, Highland, Matthew J., Eastman, Jeffrey A., Walkosz, Weronika, Zapol, Peter, Stephenson, G. Brian
Publicado 2021

Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation

por Guan, Ruifang, Lian, Tengfei, Zhou, Bing-Rui, He, Emily, Wu, Carl, Singleton, Martin, Bai, Yawen
Publicado 2021

The Impact of COVID-19 on Provider Perceptions of Telemental Health

por Doran, Jennifer M., Lawson, Jessica L.
Publicado 2021

Nesting, brood rearing, and summer habitat selection by translocated greater sage‐grouse in North Dakota, USA

por Lazenby, Kade D., Coates, Peter S., O’Neil, Shawn T., Kohl, Michel T., Dahlgren, David K.
Publicado 2021

Presenting or Spinning Facts? Deconstructing the U.S. Centers for Disease Control Statement on the Importance of Reopening Schools Under COVID-19

por Benzian, Habib, Johnston, Marilyn, Stauf, Nicole, Niederman, Richard
Publicado 2021