Modulation of the monomer-dimer equilibrium and catalytic activity of SARS-CoV-2 main protease by a transition-state analog inhibitor

por Nashed, Nashaat T., Aniana, Annie, Ghirlando, Rodolfo, Chiliveri, Sai Chaitanya, Louis, John M.
Publicado 2022

Robust Mendelian randomization in the presence of residual population stratification, batch effects and horizontal pleiotropy

por Cinelli, Carlos, LaPierre, Nathan, Hill, Brian L., Sankararaman, Sriram, Eskin, Eleazar
Publicado 2022

Cryo-EM structure and electrophysiological characterization of ALMT from Glycine max reveal a previously uncharacterized class of anion channels

por Qin, Li, Tang, Ling-hui, Xu, Jia-shu, Zhang, Xian-hui, Zhu, Yun, Zhang, Chun-rui, Wang, Mei-hua, Liu, Xue-lei, Li, Fei, Sun, Fei, Su, Min, Zhai, Yujia, Chen, Yu-hang
Publicado 2022

Clinically translatable cytokine delivery platform for eradication of intraperitoneal tumors

por Nash, Amanda M., Jarvis, Maria I., Aghlara-Fotovat, Samira, Mukherjee, Sudip, Hernandez, Andrea, Hecht, Andrew D., Rios, Peter D., Ghani, Sofia, Joshi, Ira, Isa, Douglas, Cui, Yufei, Nouraein, Shirin, Lee, Jared Z., Xu, Chunyu, Zhang, David Y., Sheth, Rahul A., Peng, Weiyi, Oberholzer, Jose, Igoshin, Oleg A., Jazaeri, Amir A., Veiseh, Omid
Publicado 2022

PAI-1 is a vascular cell–specific HIF-2–dependent angiogenic factor that promotes retinal neovascularization in diabetic patients

por Qin, Yaowu, Zhang, Jing, Babapoor-Farrokhran, Savalan, Applewhite, Brooks, Deshpande, Monika, Megarity, Haley, Flores-Bellver, Miguel, Aparicio-Domingo, Silvia, Ma, Tao, Rui, Yuan, Tzeng, Stephany Y., Green, Jordan J., Canto-Soler, M. Valeria, Montaner, Silvia, Sodhi, Akrit
Publicado 2022

Spatial monitoring technologies for coupling the soil plant water animal nexus

por Ashworth, Amanda J., Kharel, Tulsi, Sauer, Tom, Adams, Taylor C., Philipp, Dirk, Thomas, Andrew L., Owens, Phillip R.
Publicado 2022

Changes in the excitability of primary hippocampal neurons following exposure to 3.0 GHz radiofrequency electromagnetic fields

por Echchgadda, Ibtissam, Cantu, Jody C., Tolstykh, Gleb P., Butterworth, Joseph W., Payne, Jason A., Ibey, Bennett L.
Publicado 2022

Comprehensive genetic diagnosis of tandem repeat expansion disorders with programmable targeted nanopore sequencing

por Stevanovski, Igor, Chintalaphani, Sanjog R., Gamaarachchi, Hasindu, Ferguson, James M., Pineda, Sandy S., Scriba, Carolin K., Tchan, Michel, Fung, Victor, Ng, Karl, Cortese, Andrea, Houlden, Henry, Dobson-Stone, Carol, Fitzpatrick, Lauren, Halliday, Glenda, Ravenscroft, Gianina, Davis, Mark R., Laing, Nigel G., Fellner, Avi, Kennerson, Marina, Kumar, Kishore R., Deveson, Ira W.
Publicado 2022

BRN2 as a key gene drives the early primate telencephalon development

por Zhu, Xiaoqing, Guo, Yicheng, Chu, Chu, Liu, Dahai, Duan, Kui, Yin, Yu, Si, Chenyang, Kang, Yu, Yao, Junjun, Du, Xuewei, Li, Junliang, Zhao, Shumei, Ai, Zongyong, Zhu, Qingyuan, Ji, Weizhi, Niu, Yuyu, Li, Tianqing
Publicado 2022

Cross-talk between GABAergic postsynapse and microglia regulate synapse loss after brain ischemia

por Cramer, Teresa, Gill, Raminder, Thirouin, Zahra S., Vaas, Markus, Sampath, Suchita, Martineau, Fanny, Noya, Sara B., Panzanelli, Patrizia, Sudharshan, Tania J. J., Colameo, David, Chang, Philip K.-Y., Wu, Pei You, Shi, Roy, Barker, Philip A., Brown, Steven A., Paolicelli, Rosa C., Klohs, Jan, McKinney, Rebecca Anne, Tyagarajan, Shiva K.
Publicado 2022

Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice

por Martinez, David R., Schäfer, Alexandra, Leist, Sarah R., De la Cruz, Gabriela, West, Ande, Atochina-Vasserman, Elena N., Lindesmith, Lisa C., Pardi, Norbert, Parks, Robert, Barr, Maggie, Li, Dapeng, Yount, Boyd, Saunders, Kevin O., Weissman, Drew, Haynes, Barton F., Montgomery, Stephanie A., Baric, Ralph S.
Publicado 2021

Interferon α/β Decoy Receptor Encoded by a Variant in the Dryvax Smallpox Vaccine Contributes to Virulence and Correlates with Severe Vaccine Side Effects

por Liu, Ruikang, Americo, Jeffrey L., Earl, Patricia L., Villani, Jack, Cotter, Catherine A., Moss, Bernard
Publicado 2022

Tailoring sub-3.3 Å ultramicropores in advanced carbon molecular sieve membranes for blue hydrogen production

por Hu, Leiqing, Bui, Vinh T., Krishnamurthy, Ajay, Fan, Shouhong, Guo, Wenji, Pal, Sankhajit, Chen, Xiaoyi, Zhang, Gengyi, Ding, Yifu, Singh, Rajinder P., Lupion, Monica, Lin, Haiqing
Publicado 2022

KLF15 cistromes reveal a hepatocyte pathway governing plasma corticosteroid transport and systemic inflammation

por Jiang, Zhen, Elsarrag, Selma Z., Duan, Qiming, LaGory, Edward L., Wang, Zhe, Alexanian, Michael, McMahon, Sarah, Rulifson, Ingrid C., Winchester, Sarah, Wang, Yi, Vaisse, Christian, Brown, Jonathan D., Quattrocelli, Mattia, Lin, Charles Y., Haldar, Saptarsi M.
Publicado 2022

Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism

por Häusl, Alexander S., Bajaj, Thomas, Brix, Lea M., Pöhlmann, Max L., Hafner, Kathrin, De Angelis, Meri, Nagler, Joachim, Dethloff, Frederik, Balsevich, Georgia, Schramm, Karl-Werner, Giavalisco, Patrick, Chen, Alon, Schmidt, Mathias V., Gassen, Nils C.
Publicado 2022

Strong suppression of heat conduction in a laboratory replica of galaxy-cluster turbulent plasmas

por Meinecke, Jena, Tzeferacos, Petros, Ross, James S., Bott, Archie F. A., Feister, Scott, Park, Hye-Sook, Bell, Anthony R., Blandford, Roger, Berger, Richard L., Bingham, Robert, Casner, Alexis, Chen, Laura E., Foster, John, Froula, Dustin H., Goyon, Clement, Kalantar, Daniel, Koenig, Michel, Lahmann, Brandon, Li, Chikang, Lu, Yingchao, Palmer, Charlotte A. J., Petrasso, Richard D., Poole, Hannah, Remington, Bruce, Reville, Brian, Reyes, Adam, Rigby, Alexandra, Ryu, Dongsu, Swadling, George, Zylstra, Alex, Miniati, Francesco, Sarkar, Subir, Schekochihin, Alexander A., Lamb, Donald Q., Gregori, Gianluca
Publicado 2022

A Late Paleocene age for Greenland’s Hiawatha impact structure

por Kenny, Gavin G., Hyde, William R., Storey, Michael, Garde, Adam A., Whitehouse, Martin J., Beck, Pierre, Johansson, Leif, Søndergaard, Anne Sofie, Bjørk, Anders A., MacGregor, Joseph A., Khan, Shfaqat A., Mouginot, Jérémie, Johnson, Brandon C., Silber, Elizabeth A., Wielandt, Daniel K. P., Kjær, Kurt H., Larsen, Nicolaj K.
Publicado 2022

Coordinated DNA and histone dynamics drive accurate histone H2A.Z exchange

por Poyton, Matthew F., Feng, Xinyu A., Ranjan, Anand, Lei, Qin, Wang, Feng, Zarb, Jasmin S., Louder, Robert K., Park, Giho, Jo, Myung Hyun, Ye, Joseph, Liu, Sheng, Ha, Taekjip, Wu, Carl
Publicado 2022

Challenges to Remote Instruction During the Pandemic: A Qualitative Study with Primary Grade Teachers in India

por Pattnaik, Jyotsna, Nath, Nibedita, Nath, Sangeeta
Publicado 2022

Toward fully automated UED operation using two-stage machine learning model

por Zhang, Zhe, Yang, Xi, Huang, Xiaobiao, Shaftan, Timur, Smaluk, Victor, Song, Minghao, Wan, Weishi, Wu, Lijun, Zhu, Yimei
Publicado 2022