Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies

por Linsenmeier, Luise, Mohammadi, Behnam, Shafiq, Mohsin, Frontzek, Karl, Bär, Julia, Shrivastava, Amulya N., Damme, Markus, Song, Feizhi, Schwarz, Alexander, Da Vela, Stefano, Massignan, Tania, Jung, Sebastian, Correia, Angela, Schmitz, Matthias, Puig, Berta, Hornemann, Simone, Zerr, Inga, Tatzelt, Jörg, Biasini, Emiliano, Saftig, Paul, Schweizer, Michaela, Svergun, Dmitri, Amin, Ladan, Mazzola, Federica, Varani, Luca, Thapa, Simrika, Gilch, Sabine, Schätzl, Hermann, Harris, David A., Triller, Antoine, Mikhaylova, Marina, Aguzzi, Adriano, Altmeppen, Hermann C., Glatzel, Markus
Publicado 2021

Predicting master transcription factors from pan-cancer expression data

por Reddy, Jessica, Fonseca, Marcos A. S., Corona, Rosario I., Nameki, Robbin, Segato Dezem, Felipe, Klein, Isaac A., Chang, Heidi, Chaves-Moreira, Daniele, Afeyan, Lena K., Malta, Tathiane M., Lin, Xianzhi, Abbasi, Forough, Font-Tello, Alba, Sabedot, Thais, Cejas, Paloma, Rodríguez-Malavé, Norma, Seo, Ji-Heui, Lin, De-Chen, Matulonis, Ursula, Karlan, Beth Y., Gayther, Simon A., Pasaniuc, Bogdan, Gusev, Alexander, Noushmehr, Houtan, Long, Henry, Freedman, Matthew L., Drapkin, Ronny, Young, Richard A., Abraham, Brian J., Lawrenson, Kate
Publicado 2021

Solution-processable and functionalizable ultra-high molecular weight polymers via topochemical synthesis

por Anderson, Christopher L., Li, He, Jones, Christopher G., Teat, Simon J., Settineri, Nicholas S., Dailing, Eric A., Liang, Jiatao, Mao, Haiyan, Yang, Chongqing, Klivansky, Liana M., Li, Xinle, Reimer, Jeffrey A., Nelson, Hosea M., Liu, Yi
Publicado 2021

In vitro and in vivo activity of GT-1, a novel siderophore cephalosporin, and GT-055, a broad-spectrum β-lactamase inhibitor, against biothreat and ESKAPE pathogens

por Halasohoris, Stephanie A., Scarff, Jennifer M., Pysz, Lisa M., Lembirik, Sanae, Lemmon, Margaret M., Biek, Donald, Hannah, Brendan, Zumbrun, Steven D., Panchal, Rekha G.
Publicado 2021

Template switching and duplications in SARS-CoV-2 genomes give rise to insertion variants that merit monitoring

por Garushyants, Sofya K., Rogozin, Igor B., Koonin, Eugene V.
Publicado 2021

Placozoan fiber cells: mediators of innate immunity and participants in wound healing

por Mayorova, Tatiana D., Hammar, Katherine, Jung, Jae H., Aronova, Maria A., Zhang, Guofeng, Winters, Christine A., Reese, Thomas S., Smith, Carolyn L.
Publicado 2021

MON-2, a Golgi protein, mediates autophagy-dependent longevity in Caenorhabditis elegans

por Jung, Yoonji, Artan, Murat, Kim, Nari, Yeom, Jeonghun, Hwang, Ara B., Jeong, Dae-Eun, Altintas, Özlem, Seo, Keunhee, Seo, Mihwa, Lee, Dongyeop, Hwang, Wooseon, Lee, Yujin, Sohn, Jooyeon, Kim, Eun Ji E., Ju, Sungeun, Han, Seong Kyu, Nam, Hyun-Jun, Adams, Linnea, Ryu, Youngjae, Moon, Dong Jin, Kang, Chanhee, Yoo, Joo-Yeon, Park, Sang Ki, Ha, Chang Man, Hansen, Malene, Kim, Sanguk, Lee, Cheolju, Park, Seung-Yeol, Lee, Seung-Jae V.
Publicado 2021

Rapid test to assess the escape of SARS-CoV-2 variants of concern

por Heggestad, Jacob T., Britton, Rhett J., Kinnamon, David S., Wall, Simone A., Joh, Daniel Y., Hucknall, Angus M., Olson, Lyra B., Anderson, Jack G., Mazur, Anna, Wolfe, Cameron R., Oguin, Thomas H., Sullenger, Bruce A., Burke, Thomas W., Kraft, Bryan D., Sempowski, Gregory D., Woods, Christopher W., Chilkoti, Ashutosh
Publicado 2021

Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein

por Tripathi, Brajendra K., Anderman, Meghan F., Bhargava, Disha, Boccuzzi, Luciarita, Qian, Xiaolan, Wang, Dunrui, Durkin, Marian E., Papageorge, Alex G., de Miguel, Fernando J., Politi, Katerina, Walters, Kylie J., Doroshow, James H., Lowy, Douglas R.
Publicado 2021

United States medical preparedness for nuclear and radiological emergencies

por DiCarlo, Andrea L., Homer, Mary J., Coleman, C. Norman
Publicado 2021

COVID-19 Antibody Detection and Assay Performance Using Red Cell Agglutination

por Srivastava, Kshitij, West, Kamille A., De Giorgi, Valeria, Holbrook, Michael R., Bovin, Nicolai V., Henry, Stephen M., Flegel, Willy A.
Publicado 2021

A comparative study of plant volatiles induced by insect and gastropod herbivory

por Mann, Leslie, Laplanche, Diane, Turlings, Ted C. J., Desurmont, Gaylord A.
Publicado 2021

Dynamic contextual influences on social motivation and behavior in schizophrenia: a case-control network analysis

por Badal, Varsha D., Parrish, Emma M., Holden, Jason L., Depp, Colin A., Granholm, Eric
Publicado 2021

Visualizing band selective enhancement of quasiparticle lifetime in a metallic ferromagnet

por Jo, Na Hyun, Wu, Yun, Trevisan, Thaís V., Wang, Lin-Lin, Lee, Kyungchan, Kuthanazhi, Brinda, Schrunk, Benjamin, Bud’ko, S. L., Canfield, P. C., Orth, P. P., Kaminski, Adam
Publicado 2021

Community similarity and species overlap between habitats provide insight into the deep reef refuge hypothesis

por Montgomery, Anthony D., Fenner, Douglas, Donahue, Megan J., Toonen, Robert J.
Publicado 2021

Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

por Amin, Ruhul, Shukla, Anjali, Zhu, Jacqueline Jufen, Kim, Sohyoung, Wang, Ping, Tian, Simon Zhongyuan, Tran, Andy D., Paul, Debasish, Cappell, Steven D., Burkett, Sandra, Liu, Huaitian, Lee, Maxwell P., Kruhlak, Michael J., Dwyer, Jennifer E., Simpson, R. Mark, Hager, Gordon L., Ruan, Yijun, Hunter, Kent W.
Publicado 2021

Using a climate attribution statistic to inform judgments about changing fisheries sustainability

por Litzow, Michael A., Malick, Michael J., Abookire, Alisa A., Duffy-Anderson, Janet, Laurel, Benjamin J., Ressler, Patrick H., Rogers, Lauren A.
Publicado 2021

Estimating the strength of selection for new SARS-CoV-2 variants

por Dorp, Christiaan H. van, Goldberg, Emma E., Hengartner, Nick, Ke, Ruian, Romero-Severson, Ethan O.
Publicado 2021

Harmony COVID-19: A ready-to-use kit, low-cost detector, and smartphone app for point-of-care SARS-CoV-2 RNA detection

por Panpradist, Nuttada, Kline, Enos C., Atkinson, Robert G., Roller, Michael, Wang, Qin, Hull, Ian T., Kotnik, Jack H., Oreskovic, Amy K., Bennett, Crissa, Leon, Daniel, Lyon, Victoria, Gilligan-Steinberg, Shane D., Han, Peter D., Drain, Paul K., Starita, Lea M., Thompson, Matthew J., Lutz, Barry R.
Publicado 2021

Prevalence of Municipal-Level Policies Dedicated to Transportation That Consider Food Access

por Dumas, Brianna L., Harris, Diane M., McMahon, Jean M., Daymude, Thomas J., Warnock, Amy Lowry, Moore, Latetia V., Onufrak, Stephen J.
Publicado 2021