A modified vaccinia Ankara vaccine expressing spike and nucleocapsid protects rhesus macaques against SARS-CoV-2 delta infection

por Routhu, Nanda Kishore, Gangadhara, Sailaja, Lai, Lilin, Davis Gardner, Meredith Elizabeth, Floyd, Katharine, Shiferaw, Ayalnesh, Bartsch, Yannic C, Fischinger, Stephanie, Khoury, Georges, Rahman, Sheikh Abdul, Stampfer, Samuel David, Schaefer, Alexandra, Jean, Sherrie M., Wallace, Chelsea, Stammen, Rachelle L., Wood, Jennifer, Cohen, Joyce, Nagy, Tamas, Parsons, Matthew S., Gralinski, Lisa, Kozlowski, Pamela A., Alter, Galit, Suthar, Mehul S., Amara, Rama Rao
Publicado 2022

Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice

por Schäfer, Alexandra, Martinez, David R., Won, John J., Meganck, Rita M., Moreira, Fernando R., Brown, Ariane J., Gully, Kendra L., Zweigart, Mark R., Conrad, William S., May, Samantha R., Dong, Stephanie, Kalla, Rao, Chun, Kwon, Du Pont, Venice, Babusis, Darius, Tang, Jennifer, Murakami, Eisuke, Subramanian, Raju, Barrett, Kimberly T., Bleier, Blake J., Bannister, Roy, Feng, Joy Y., Bilello, John P., Cihlar, Tomas, Mackman, Richard L., Montgomery, Stephanie A., Baric, Ralph S., Sheahan, Timothy P.
Publicado 2022

Heterogeneity of neuroendocrine transcriptional states in metastatic small cell lung cancers and patient-derived models

por Lissa, Delphine, Takahashi, Nobuyuki, Desai, Parth, Manukyan, Irena, Schultz, Christopher W., Rajapakse, Vinodh, Velez, Moises J., Mulford, Deborah, Roper, Nitin, Nichols, Samantha, Vilimas, Rasa, Sciuto, Linda, Chen, Yuanbin, Guha, Udayan, Rajan, Arun, Atkinson, Devon, El Meskini, Rajaa, Weaver Ohler, Zoe, Thomas, Anish
Publicado 2022

Naloxone’s dose-dependent displacement of [(11)C]carfentanil and duration of receptor occupancy in the rat brain

por Kang, Yeona, O’Conor, Kelly A., Kelleher, Andrew C., Ramsey, Joseph, Bakhoda, Abolghasem, Eisenberg, Seth M., Zhao, Wenjing, Stodden, Tyler, Pearson, Torben D., Guo, Min, Brown, Nina, Liow, Jeih-San, Fowler, Joanna S., Kim, Sung Won, Volkow, Nora D.
Publicado 2022

BNT162b2 vaccination enhances interferon-JAK-STAT-regulated antiviral programs in COVID-19 patients infected with the SARS-CoV-2 Beta variant

por Knabl, Ludwig, Lee, Hye Kyung, Wieser, Manuel, Mur, Anna, Zabernigg, August, Knabl, Ludwig, Rauch, Simon, Bock, Matthias, Schumacher, Jana, Kaiser, Norbert, Furth, Priscilla A., Hennighausen, Lothar
Publicado 2022

Preferences for Long-Acting and Alternative Modalities for PrEP among Military Men Who Have Sex with Men: Segmentation Results of an Adaptive Choice-Based Conjoint Analysis Study

por Gutierrez, Jose I., Vlahov, David, Dubov, Alex, Altice, Frederick L.
Publicado 2022

Comparative Genomics of Cyclic di-GMP Metabolism and Chemosensory Pathways in Shewanella algae Strains: Novel Bacterial Sensory Domains and Functional Insights into Lifestyle Regul...

por Martín-Rodríguez, Alberto J., Higdon, Shawn M., Thorell, Kaisa, Tellgren-Roth, Christian, Sjöling, Åsa, Galperin, Michael Y., Krell, Tino, Römling, Ute
Publicado 2022

Comparison of Wrist- and Hip-Worn Activity Monitors When Meeting Step Guidelines

por Nelson, Rachael K., Hasanaj, Kristina, Connolly, Gavin, Millen, Laramy, Muench, Joshua, Bidolli, Nicole S.C., Preston, Michael A., Montoye, Alexander H.K.
Publicado 2022

Behavior of potentially toxic elements from stoker-boiler fly ash in Interior Alaska: paired batch leaching and solid-phase characterization

por Milke, Kyle P., Mitchell, Kiana L., Hayes, Sarah M., Green, Carlin J., Guerard, Jennifer J.
Publicado 2021

An evaluation of the National Institutes of Health grants portfolio: identifying opportunities and challenges for multi-omics research that leverage metabolomics data

por Yu, Catherine T., Chao, Brittany N., Barajas, Rolando, Haznadar, Majda, Maruvada, Padma, Nicastro, Holly L., Ross, Sharon A., Verma, Mukesh, Rogers, Scott, Zanetti, Krista A.
Publicado 2022

Age‐dependent white matter disruptions after military traumatic brain injury: Multivariate analysis results from ENIGMA brain injury

por Bouchard, Heather C., Sun, Delin, Dennis, Emily L., Newsome, Mary R., Disner, Seth G., Elman, Jeremy, Silva, Annelise, Velez, Carmen, Irimia, Andrei, Davenport, Nicholas D., Sponheim, Scott R., Franz, Carol E., Kremen, William S., Coleman, Michael J., Williams, M. Wright, Geuze, Elbert, Koerte, Inga K., Shenton, Martha E., Adamson, Maheen M., Coimbra, Raul, Grant, Gerald, Shutter, Lori, George, Mark S., Zafonte, Ross D., McAllister, Thomas W., Stein, Murray B., Thompson, Paul M., Wilde, Elisabeth A., Tate, David F., Sotiras, Aristeidis, Morey, Rajendra A.
Publicado 2022

Comparative metabolomic analysis in plasma and cerebrospinal fluid of humans and in plasma and brain of mice following antidepressant-dose ketamine administration

por Moaddel, Ruin, Zanos, Panos, Farmer, Cristan A., Kadriu, Bashkim, Morris, Patrick J., Lovett, Jacqueline, Acevedo-Diaz, Elia E., Cavanaugh, Grace W., Yuan, Peixiong, Yavi, Mani, Thomas, Craig J., Park, Lawrence T., Ferrucci, Luigi, Gould, Todd D., Zarate, Carlos A.
Publicado 2022

Outcomes in heart failure patients discharged to skilled nursing facilities with delirium

por Lafo, Jacob, Singh, Mriganka, Jiang, Lan, Correia, Stephen, Madrigal, Caroline, Clements, Rachel, Wu, Wen‐Chih, Erqou, Sebhat, Rudolph, James L.
Publicado 2022

Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis

por Li, Ying, Talbot, Chad Lamar, Chandravanshi, Bhawna, Ksiazek, Alec, Sood, Ayushi, Chowdhury, Kamrul Hasan, Maschek, J. Alan, Cox, James, Babu, Adhini Kuppuswamy Satheesh, Paz, Henry A., Babu, Pon Velayutham Anandh, Meyerholz, David K., Wankhade, Umesh D., Holland, William, Shyong Tai, E., Summers, Scott A., Chaurasia, Bhagirath
Publicado 2022

Genetics of Type 2 Diabetes: Implications from Large-Scale Studies

por DeForest, Natalie, Majithia, Amit R.
Publicado 2022

A short hepatitis C virus NS5A peptide expression by AAV vector modulates human T cell activation and reduces vector immunogenicity

por Colon-Moran, Winston, Baer, Alan, Lamture, Gauri, Stapleton, Jack T., Fischer, Joseph W., Bhattarai, Nirjal
Publicado 2021

Mutations in the SARS-CoV-2 RNA dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms

por Stevens, Laura J., Pruijssers, Andrea J., Lee, Hery W., Gordon, Calvin J., Tchesnokov, Egor P., Gribble, Jennifer, George, Amelia S., Hughes, Tia M., Lu, Xiaotao, Li, Jiani, Perry, Jason K., Porter, Danielle P., Cihlar, Tomas, Sheahan, Timothy P., Baric, Ralph S., Götte, Matthias, Denison, Mark R.
Publicado 2022

Ruminative reflection is associated with anticorrelations between the orbitofrontal cortex and the default mode network in depression: implications for repetitive transcranial magn...

por Ehrlich, Tobin J., Bhat, Jyoti, Horwege, Andrea M., Mathalon, Daniel H., Glover, Gary H., Roach, Brian J., Badran, Bashar W., Forman, Steven D., George, Mark S., Scott, J. Cobb, Thase, Michael E., Yesavage, Jerome A., Yurgelun-Todd, Deborah A., Rosen, Allyson C.
Publicado 2021

Development of a clinical polygenic risk score assay and reporting workflow

por Hao, Limin, Kraft, Peter, Berriz, Gabriel F., Hynes, Elizabeth D., Koch, Christopher, Korategere V Kumar, Prathik, Parpattedar, Shruti S., Steeves, Marcie, Yu, Wanfeng, Antwi, Ashley A., Brunette, Charles A., Danowski, Morgan, Gala, Manish K., Green, Robert C., Jones, Natalie E., Lewis, Anna C. F., Lubitz, Steven A., Natarajan, Pradeep, Vassy, Jason L., Lebo, Matthew S.
Publicado 2022

Design of protein-binding proteins from the target structure alone

por Cao, Longxing, Coventry, Brian, Goreshnik, Inna, Huang, Buwei, Sheffler, William, Park, Joon Sung, Jude, Kevin M., Marković, Iva, Kadam, Rameshwar U., Verschueren, Koen H. G., Verstraete, Kenneth, Walsh, Scott Thomas Russell, Bennett, Nathaniel, Phal, Ashish, Yang, Aerin, Kozodoy, Lisa, DeWitt, Michelle, Picton, Lora, Miller, Lauren, Strauch, Eva-Maria, DeBouver, Nicholas D., Pires, Allison, Bera, Asim K., Halabiya, Samer, Hammerson, Bradley, Yang, Wei, Bernard, Steffen, Stewart, Lance, Wilson, Ian A., Ruohola-Baker, Hannele, Schlessinger, Joseph, Lee, Sangwon, Savvides, Savvas N., Garcia, K. Christopher, Baker, David
Publicado 2022