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  1. 2521
    “…In contrast, the folate-based 1843U89 was a potent inhibitor of ThyA but not ThyX suggesting that it should be possible to find ThyX-specific antifolates. …”
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    Kinetics and Ligand-Binding Preferences of Mycobacterium tuberculosis Thymidylate Synthases, ThyA and ThyX
  2. 2522
    “…PAI-1, CATB and uPA demonstrated a better accuracy than CEA or CA 19-9. …”
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    Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer
  3. 2523
    “…CONCLUSION: Primary consideration for a P/U tag was a visit characterized by a behaviorally disturbed state and/or, suicidal ideation (or attempts) within the context of either an underlying psychotic or affective disorder, especially if poor judgment was an issue. …”
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    A qualitative study of a psychiatric emergency
  4. 2524
    “…CONCLUSION: The results obtained in this study suggest a role of uPAR as a potential biomarker useful to identify higher risk subgroups of OSCC patients.…”
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    Prognostic value analysis of urokinase-type plasminogen activator receptor in oral squamous cell carcinoma: an immunohistochemical study
  5. 2525
    “…They represent CRF27_cpx involving A/E/G/H/J/K/U subtypes. 06FR-CRN, isolated in a homosexual Caucasian patient, was a B/C/U recombinant involving a Brazilian C strain. 04FR-AUK, isolated in a Congolese patient infected in France, was a A/K/CRF09/U recombinant clustering from gag to vif with HIV-1 MAL. …”
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    New and old complex recombinant HIV-1 strains among patients with primary infection in 1996–2006 in France: The French ANRS CO06 primo cohort study
  6. 2526
    “…CONCLUSION: In the context of a PB2-like reporter vRNA template, the sequence upstream the polyU stretch plays a role in the transcription/replication process by the type C polymerase complex.…”
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    Non coding extremities of the seven influenza virus type C vRNA segments: effect on transcription and replication by the type C and type A polymerase complexes
  7. 2527
    “…Urokinase-type plasminogen activator receptor (uPAR) plays a central role in the plasminogen activation cascade and participates in extracellular matrix degradation, cell migration and invasion. …”
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    Expression of uPAR mRNA in peripheral blood is a favourite marker for metastasis in gastric cancer cases
  8. 2528
    “…AA was expectedly more potent and exhibiting at 150 uM dose a 5-fold increase in PGE(2 )secretion over EPA. …”
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    n3 and n6 polyunsaturated fatty acids differentially modulate prostaglandin E secretion but not markers of lipogenesis in adipocytes
  9. 2529
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    Is Age-Related Macular Degeneration Associated with Stroke Among Elderly Americans?
  10. 2530
    “…In the absence of DNA, RecU accumulated at a single cell pole in competent cells, dependent on RecA. …”
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    Evidence for Different Pathways during Horizontal Gene Transfer in Competent Bacillus subtilis Cells
  11. 2531
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    Prostate cancer incidence among finasteride and alpha-blocker users in the Finnish Prostate Cancer Screening Trial
  12. 2532
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    Iron Labeling and Pre-Clinical MRI Visualization of Therapeutic Human Neural Stem Cells in a Murine Glioma Model
  13. 2533
    “…Thus, our study further supports a role for TWEAK in the pathogenesis of LN, and provides strong evidence for uTWEAK as a candidate clinical biomarker for LN.…”
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    Urinary TWEAK as a biomarker of lupus nephritis: a multicenter cohort study
  14. 2534
    “…Moreover our analyses reveal an unanticipated plasticity of embryo-derived plasmatocytes, thereby shedding new light on blood cell lineage relationship, and pinpoint the Friend of GATA transcription cofactor U-shaped as a key regulator of the plasmatocyte to lamellocyte transformation.…”
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    An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis
  15. 2535
    “…NMR investigation showed that U3 gave a faster rate of polymerization in comparison to U1. …”
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    Synthesis and crossover reaction of TEMPO containing block copolymer via ROMP
  16. 2536
    “…The amino terminal fragment of uPA down regulated ruPA-induced angiogenin in endothelial cells, thereby suggesting that uPA plays a critical role in positively regulating angiogenin in glioblastoma cells. …”
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    Suppression of uPA and uPAR Attenuates Angiogenin Mediated Angiogenesis in Endothelial and Glioblastoma Cell Lines
  17. 2537
    “…BACKGROUND: The PRIMUS is a Multiple Sclerosis (MS)-specific suite of outcome measures including assessments of QoL (PRIMUS QoL, scored 0-22) and activity limitations (PRIMUS Activities, scored 0-30). The U-FIS is a measure of fatigue impact (scored 0-66). …”
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    Interpreting scores on multiple sclerosis-specific patient reported outcome measures (the PRIMUS and U-FIS)
  18. 2538
    “…U-46619 significantly augmented the CBF-oscillations induced by L-NAME while inhibition of endogenous TXA(2) synthesis by ozagrel (10 mg/kg iv.) attenuated it. In isolated MCAs U-46619 in a concentration of 100 nM, which induced weak and stable contraction under physiological conditions, evoked sustained vasomotion in the absence of NO, which effect could be completely reversed by inhibition of Rho-kinase by 10 µM Y-27632. …”
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    Hypersensitivity to Thromboxane Receptor Mediated Cerebral Vasomotion and CBF Oscillations during Acute NO-Deficiency in Rats
  19. 2539
    “…Pr uptake occurred at doses lower than required for death in three of the cell lines: 656 J/g for CHO-K1, 634 J/g for HeLa, and 142 J/g for GH3. Both Jurkat and U937 had a LD(50) lower than the ED(50) for Pr uptake at 780 J/g and 1274 J/g, respectively. …”
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    Dose-Dependent Thresholds of 10-ns Electric Pulse Induced Plasma Membrane Disruption and Cytotoxicity in Multiple Cell Lines
  20. 2540
    “…We also show that the galU mutant had a hypercytotoxic phenotype and more rapidly induced the production of IL-1β following infection either in vitro or in vivo, indicating that attenuation of the galU mutant strain may be due (in part) to more rapid activation of the inflammasome and/or earlier death of FT infected cells. …”
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    A galU mutant of francisella tularensis is attenuated for virulence in a murine pulmonary model of tularemia
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