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2541“…Here, stably-transfected U937 cells with a pMTH1 vector containing the β(2 )integrin gene of CD11b in antisense orientation (asCD11b-U937) demonstrated a significantly reduced proliferative capacity in contrast to control vector transfectants (pMTH1-U937) or wild-type U937 cells. …”
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2542por Oyeyemi, Adewale L, Oyeyemi, Adetoyeje Y, Adegoke, Babatunde O, Oyetoke, Fatima O, Aliyu, Habeeb N, Aliyu, Salamatu U, Rufai, Adamu AEnlace del recurso
Publicado 2011
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2543por Biesen, Robert, Dähnrich, Cornelia, Rosemann, Anke, Barkhudarova, Fidan, Rose, Thomas, Jakob, Olga, Bruns, Anne, Backhaus, Marina, Stöcker, Winfried, Burmester, Gerd-Rüdiger, Schlumberger, Wolfgang, Egerer, Karl, Hiepe, Falk“…RESULTS: The Anti-dsDNA-NcX ELISA was found to have a sensitivity of 60.9% and a specificity of 98.9% in all 964 individuals at the manufacturer's cutoff of 100 U/ml. At a comparable specificity of 99%, the sensitivity amounted to 59.9% for the Anti-dsDNA-NcX ELISA, 54.1% for the Farr assay, 53.6% for the antinucleosome ELISA and 35.8% for the anti-dsDNA ELISA. …”
Publicado 2011
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2544
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2545por Gorgal, Tiago, Charrua, Ana, Silva, João F, Avelino, António, Dinis, Paulo, Cruz, Francisco“…METHODS: Adult Wistar rats were injected in the ventral lobes of the prostate with 10 U of OnabotA or saline. A set of OnabotA-injected animals was further treated with 0.5 mg/kg of phenylephrine (PHE) subcutaneously daily. …”
Publicado 2012
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2546por d'Emmanuele di Villa Bianca, Roberta, Mitidieri, Emma, Fusco, Ferdinando, D'Aiuto, Elena, Grieco, Paolo, Novellino, Ettore, Imbimbo, Ciro, Mirone, Vincenzo, Cirino, Giuseppe, Sorrentino, Raffaella“…BACKGROUND: Urotensin II (U-II) is a cyclic peptide originally isolated from the neurosecretory system of the teleost fish and subsequently found in other species, including man. …”
Publicado 2012
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2547“…Adhesion assay demonstrated that wild type cells adhered most efficiently to laminin, whereas siRNA-treated cells (p<0.0001 for both CD44 and CD155 expression) showed decreased adhesion on several ECMs investigated. BrdU assay showed a higher proliferation of siRNA-CD44 and siRNA-CD155 cells, inversely correlated with reduced invasion. …”
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2548por Soto-Reyes, Ernesto, González-Barrios, Rodrigo, Cisneros-Soberanis, Fernanda, Herrera-Goepfert, Roberto, Pérez, Víctor, Cantú, David, Prada, Diddier, Castro, Clementina, Recillas-Targa, Félix, Herrera, Luis A“…The miR-125b1 gene expression was analyzed by qRT-PCR using U6 as a control for constitutive gene expression. …”
Publicado 2012
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2549por Haupt, Armin, Joberty, Gerard, Bantscheff, Marcus, Fröhlich, Holger, Stehr, Henning, Schweiger, Michal R, Fischer, Axel, Kerick, Martin, Boerno, Stefan T, Dahl, Andreas, Lappe, Michael, Lehrach, Hans, Gonzalez, Cayetano, Drewes, Gerard, Lange, Bodo MH“…METHODS: We quantitatively profiled the effects of Hsp90 inhibition by geldanamycin on the kinome of one primary (Hs68) and three tumour cell lines (SW480, U2OS, A549) by affinity proteomics based on immobilized broad spectrum kinase inhibitors ("kinobeads"). …”
Publicado 2012
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2550por Klement, Tobias, Milker, Sofia, Jäger, Gernot, Grande, Philipp M, Domínguez de María, Pablo, Büchs, Jochen“…CONCLUSION: The fungus U. maydis is a promising producer of itaconic acid, since it grows as single cells (yeast-like) in submerged cultivations and it is extremely robust in high osmotic media and real seawater. …”
Publicado 2012
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2551por Cabeza, Carolina, Figueroa, Alicia, Lazo, Oscar M, Galleguillos, Carolina, Pissani, Claudia, Klein, Andrés, Gonzalez-Billault, Christian, Inestrosa, Nibaldo C, Alvarez, Alejandra R, Zanlungo, Silvana, Bronfman, Francisca C“…As models, we used i) NPC1-deficient mice to evaluate the central cholinergic septo-hippocampal pathway and its response to nerve growth factor (NGF) after axotomy and ii) PC12 cells treated with U18666A, a pharmacological cellular model of NPC, stimulated with NGF. …”
Publicado 2012
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2552“…Result: Instead of treating the unknown genes as negative examples in N, we treat them as an unlabeled set U. We design a novel positive-unlabeled (PU) learning algorithm PUDI (PU learning for disease gene identification) to build a classifier using P and U. …”
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2553“…To determine influenza effects on P(a)O(2):F(i)O(2), mice were challenged with 10 000 p.f..u./mouse influenza A/WSN/33. Results P(a)O(2):F(i)O(2) ratios were abnormally low (≤400 mmHg) in spontaneously breathing mice. …”
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2554por Klawitter, Marina, Quero, Lilian, Klasen, Juergen, Gloess, Alexia N, Klopprogge, Babette, Hausmann, Oliver, Boos, Norbert, Wuertz, Karin“…Quantitative data was statistically analyzed using a Mann Whitney U test with a significance level of p < 0.05 (two-tailed). …”
Publicado 2012
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2555por Woolard, Matthew D., Barrigan, Lydia M., Fuller, James R., Buntzman, Adam S., Bryan, Joshua, Manoil, Colin, Kawula, Thomas H., Frelinger, Jeffrey A.“…We found that U112 clpB::Tn grows within macrophages yet fails to induce PGE(2), while U112 pdpA::Tn does not grow yet does induce PGE(2). …”
Publicado 2013
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2556por Der Sarkissian, Clio, Balanovsky, Oleg, Brandt, Guido, Khartanovich, Valery, Buzhilova, Alexandra, Koshel, Sergey, Zaporozhchenko, Valery, Gronenborn, Detlef, Moiseyev, Vyacheslav, Kolpakov, Eugen, Shumkin, Vladimir, Alt, Kurt W., Balanovska, Elena, Cooper, Alan, Haak, Wolfgang“…Mesolithic foragers showed high frequencies and diversity of haplogroups U (U2e, U4, U5a), a pattern observed previously in European hunter-gatherers from Iberia to Scandinavia. …”
Publicado 2013
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2557por Nabal, Maria, Barcons, Miquel, Moreno, Roberto, Busquets, Xavier, Trujillano, Javier J, Requena, Antonio“…We developed a comparison between groups by Chi-squared test or the non-parametric Mann–Whitney U test and a survival analysis by Kaplan-Meier curves and the logrank test to determine differences between factors. …”
Publicado 2013
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2558por Burford, B, Gentry-Maharaj, A, Graham, R, Allen, D, Pedersen, J W, Nudelman, A S, Blixt, O, Fourkala, E O, Bueti, D, Dawnay, A, Ford, J, Desai, R, David, L, Trinder, P, Acres, B, Schwientek, T, Gammerman, A, Reis, C A, Silva, L, Osório, H, Hallett, R, Wandall, H H, Mandel, U, Hollingsworth, M A, Jacobs, I, Fentiman, I, Clausen, H, Taylor-Papadimitriou, J, Menon, U, Burchell, J MEnlace del recurso
Publicado 2013
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2559por Gunier, Robert B., Horn-Ross, Pamela L., Canchola, Alison J., Duffy, Christine N., Reynolds, Peggy, Hertz, Andrew, Garcia, Erika, Rull, Rudolph P.“…Conclusion: U-Cd levels varied with several individual characteristics, and a single measurement of U-Cd in a 24-hr sample did not accurately reflect medium- to long-term body burden.…”
Publicado 2013
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2560“…Results: Mean (± SD) AChE activity was 3.14 ± 0.49 U/mL. A 1-U/mL decrease in AChE activity was associated with a 2.86-mmHg decrease in SBP (95% CI: –5.20, –0.53) and a 2.89-mmHg decrease in DBP (95% CI: –5.00, –0.78), after adjustment for potential confounders. …”
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