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2881Publicado 1994“…In vivo, CK8, and to a lesser degree CK18, were found to be phosphorylated on serine residues. Occupation of uPAR elicited a time-dependent increase in the phosphorylation intensity of CK8, a cell shape change and a redistribution of the cytokeratin filaments. …”
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2882“…Continued culture of primed spleen cells in the presence of poly A:U, resulted in a decrease of RFC to background levels within an hour followed by an increase again 6 hr later. …”
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2883por Määttänen, L, Hakama, M, Tammela, T L J, Ruutu, M, Ala-Opas, M, Juusela, H, Martikainen, P, Stenman, U-H, Auvinen, AEnlace del recurso
Publicado 2007
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2884por Strasberg, Steven M.“…Multivariate analysis disclosed that coexistent hepatolithiasis and lower serum asparate aminotransferase levels (90 U/L) had a significant low incidence of postoperative morbidity, whereas a serum albumin of less than 3 g/dL was the only significant factor affecting mortality. …”
Publicado 1998
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2885por Lee, Robert J., Harlow, Janice M., Limberis, Maria P., Wilson, James M., Foskett, J. Kevin“…During carbachol (CCh) stimulation, pH(i) fell transiently by 0.08 ± 0.01 U concomitantly with a fall in Cl(−) content revealed by cell shrinkage, reflecting Cl(−) secretion. …”
Publicado 2008
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2886por Lawless, Craig, Pearson, Richard D, Selley, Julian N, Smirnova, Julia B, Grant, Christopher M, Ashe, Mark P, Pavitt, Graham D, Hubbard, Simon J“…In the first genome-wide study of uORFs in a set of mapped 5' UTRs, we show that uORFs are rare, being statistically under-represented in UTR sequences. …”
Publicado 2009
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2887“…LPS upregulates u-PA and u-PAR in a dose-dependent manner, enhancing in vitro tumour cell vitronectin adhesion and ECM invasion by >40% (P<0.01). …”
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2888“…We found that vectors packaged using mutated U(L)13 (a protein kinase), or VP16, or U(L)46 and/or U(L)47 (components of the VP16 transcriptional complex) supported improved long-term expression, and vectors packaged using mutated U(L)46 and/or U(L)47 also supported improved gene transfer (numbers of cells at 4 days). …”
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2889
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2890“…We have recently identified UPAR as an asthma susceptibility gene and there is evidence to suggest that uPAR may be upregulated in lung diseases such as COPD and asthma. uPAR is a key receptor involved in the formation of the serine protease plasmin by interacting with uPA and has been implicated in many physiological processes including proliferation and migration. …”
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2891por Cook, Andrew D, De Nardo, Christine M, Braine, Emma L, Turner, Amanda L, Vlahos, Ross, Way, Kerrie J, Beckman, S Kaye, Lenzo, Jason C, Hamilton, John A“…Neutrophilia was induced in the peritoneal cavity using either ovalbumin/anti-ovalbumin or the complement component C5a. RESULTS: u-PA from a bone marrow-derived cell was required for the full development of CIA. …”
Publicado 2010
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2892por Dibble, Christopher F., Horst, Jeremy A., Malone, Michael H., Park, Kun, Temple, Brenda, Cheeseman, Holly, Barbaro, Justin R., Johnson, Gary L., Bencharit, Sompop“…PDCD10 appears to be a six-helical-bundle protein formed by two heptad-repeat-hairpin structures (α1–3 and α4–6) sharing the closest 3D homology with the bacterial phosphate transporter, PhoU. We identified a stretch of five lysines forming an amphipathic helix, a potential PtdIns(3,4,5)P3 binding site, in the α5 helix. …”
Publicado 2010
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2893
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2894por Eisele, Marion, Zimmermann, Thomas, Köhler, Mirjam, Wiese, Birgitt, Heser, Kathrin, Tebarth, Franziska, Weeg, Dagmar, Olbrich, Julia, Pentzek, Michael, Fuchs, Angela, Weyerer, Siegfried, Werle, Jochen, Leicht, Hanna, König, Hans-Helmut, Luppa, Melanie, Riedel-Heller, Steffi, Maier, Wolfgang, Scherer, Martin“…Perceived social support was assessed using the 14-item version of the FSozU, which is a standardised and validated questionnaire of social support. …”
Publicado 2012
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2895por Popugaev, Konstantin A, Savin, Ivan A, Lubnin, Andrew U, Goriachev, Alexander S, Kadashev, Boris A, Kalinin, Pavel L, Oshorov, Andrew V, Polupan, Alexander A, Sokolova, Ekaterina U, Kutin, Maxim A, Lukianov, Valeriy IEnlace del recurso
Publicado 2012
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2896por Engström, Karin, Ameer, Shegufta, Bernaudat, Ludovic, Drasch, Gustav, Baeuml, Jennifer, Skerfving, Staffan, Bose-O’Reilly, Stephan, Broberg, Karin“…MRP2 SNPs showed particularly strong associations with U-Hg in the subgroup with highest exposure (miners in Zimbabwe), whereas rs1885301 A–allele carriers had higher U-Hg than GG homozygotes [geometric mean (GM): 36.4 µg/g creatinine vs. 21.9; p = 0.027], rs2273697 GG homozygotes had higher U-Hg than A–allele carriers (GM: 37.4 vs. 16.7; p = 0.001), and rs717620 A–allele carriers had higher U-Hg than GG homozygotes (GM: 83 vs. 28; p = 0.084). …”
Publicado 2012
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2897por Mirković, Katarina, Doorenbos, Carolina R. C., Dam, Wendy A., Lambers Heerspink, Hiddo J., Slagman, Maartje C. J., Nauta, Ferdau L., Kramer, Andrea B., Gansevoort, Ronald T., van den Born, Jacob, Navis, Gerjan, de Borst, Martin H.“…We investigated the value of urinary vitamin D binding protein excretion (uVDBP) as a tubulointerstitial inflammation and fibrosis marker in adriamycin rats, and tested whether uVDBP parallels renal damage and responds to therapy intensification in humans. …”
Publicado 2013
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2898“…PEL168P had a specific activity of 1320 U/mg with a K(m) of 0.09 mg/ml and a V(max) of 18.13 μmol/min. …”
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2899por Jensen, Ole Kudsk, Stengaard-Pedersen, Kristian, Jensen, Chris, Nielsen, Claus Vinther“…The model predicted all three risk categories in initial U-RTW. CONCLUSIONS: A prediction model combining baseline clinical and psychosocial risk factors predicted patients with low, intermediate and high risk for unsuccessful return to work, both initially and at 1-year.…”
Publicado 2013
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2900por Zaw, Myo Thura, Yamasaki, Eiki, Yamamoto, Shingo, Nair, G Balakrish, Kawamoto, Keiko, Kurazono, Hisao“…To purify Usp protein, we employed the expression vector encoding untagged Usp together with OrfU1-His. A tight complex formation could be observed between Usp and OrfU1-His, which allowed the purification of Usp in a single chromatographic step: binding of Usp/OrfU1-His complex to Ni(2+) chelating agarose followed by elution of Usp from the complex with denaturing reagent. …”
Publicado 2013
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