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  1. 3441
    “…We collected electronic laboratory records data of PC and non-PC patients and used the Student test or Mann–Whitney U test for a retrospective study. Logistic regression was used to identify risk factors associated with persistent candidemia. …”
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    Epidemiology, antifungal susceptibility, risk factors, and mortality of persistent candidemia in adult patients in China: a 6-year multicenter retrospective study
  2. 3442
    “…RESULTS: EVs isolated by either ultracentrifugation alone or TFF-U/C displayed comparable size distribution (~ 50–350 nm) and EV marker expression (CD63/81). TFF-U/C generated a 5.4-fold higher particle concentration and 3.9-fold higher total protein when compared to ultracentrifugation alone. …”
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    Biodistribution of mesenchymal stromal cell-derived extracellular vesicles administered during acute lung injury
  3. 3443
    “…METHODS: Samples encompassed T98G, U87, and A172 human GBM cell lines, GBM tumors from Puerto Rican patients, and murine tumors. …”
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    MicroRNA-92b targets tumor suppressor gene FBXW7 in glioblastoma
  4. 3444
    “…Patient was on CIIS with regular insulin U-500 using a total daily dose of 95 units. She referred amenorrhea for the past 12 years and significant progression of hirsutism, alopecia and acanthosis nigricans in the past two years. …”
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    SAT364 A Rare Cause of Hyperandrogenism in a Premenopausal Woman
  5. 3445
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    THU091 Hypopituitarism And The Finding Of Hyperprolactinemia Following Mild Traumatic Brain Injury In Female Athletes
  6. 3446
    “…Prior to piloting PMC implementation in southern Togo, a household survey was conducted to estimate malaria infection prevalence in children under 2 years of age (U2). METHODS: A cross-sectional community-based household survey was conducted in the Haho district in the Togo Plateaux region. …”
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    Prevalence and risk factors associated with malaria infection in children under two years of age in southern Togo prior to perennial malaria chemoprevention implementation
  7. 3447
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    477. Characteristics and Long-Term Outcomes of Cardiac Complications of SARS-CoV-2 in Youth: Results from the EPICC YES C3 Prospective Longitudinal Cohort Module
  8. 3448
    por Strawbridge, Rona J., Dupuis, Josée, Prokopenko, Inga, Barker, Adam, Ahlqvist, Emma, Rybin, Denis, Petrie, John R., Travers, Mary E., Bouatia-Naji, Nabila, Dimas, Antigone S., Nica, Alexandra, Wheeler, Eleanor, Chen, Han, Voight, Benjamin F., Taneera, Jalal, Kanoni, Stavroula, Peden, John F., Turrini, Fabiola, Gustafsson, Stefan, Zabena, Carina, Almgren, Peter, Barker, David J.P., Barnes, Daniel, Dennison, Elaine M., Eriksson, Johan G., Eriksson, Per, Eury, Elodie, Folkersen, Lasse, Fox, Caroline S., Frayling, Timothy M., Goel, Anuj, Gu, Harvest F., Horikoshi, Momoko, Isomaa, Bo, Jackson, Anne U., Jameson, Karen A., Kajantie, Eero, Kerr-Conte, Julie, Kuulasmaa, Teemu, Kuusisto, Johanna, Loos, Ruth J.F., Luan, Jian'an, Makrilakis, Konstantinos, Manning, Alisa K., Martínez-Larrad, María Teresa, Narisu, Narisu, Nastase Mannila, Maria, Öhrvik, John, Osmond, Clive, Pascoe, Laura, Payne, Felicity, Sayer, Avan A., Sennblad, Bengt, Silveira, Angela, Stančáková, Alena, Stirrups, Kathy, Swift, Amy J., Syvänen, Ann-Christine, Tuomi, Tiinamaija, van 't Hooft, Ferdinand M., Walker, Mark, Weedon, Michael N., Xie, Weijia, Zethelius, Björn, Ongen, Halit, Mälarstig, Anders, Hopewell, Jemma C., Saleheen, Danish, Chambers, John, Parish, Sarah, Danesh, John, Kooner, Jaspal, Östenson, Claes-Göran, Lind, Lars, Cooper, Cyrus C., Serrano-Ríos, Manuel, Ferrannini, Ele, Forsen, Tom J., Clarke, Robert, Franzosi, Maria Grazia, Seedorf, Udo, Watkins, Hugh, Froguel, Philippe, Johnson, Paul, Deloukas, Panos, Collins, Francis S., Laakso, Markku, Dermitzakis, Emmanouil T., Boehnke, Michael, McCarthy, Mark I., Wareham, Nicholas J., Groop, Leif, Pattou, François, Gloyn, Anna L., Dedoussis, George V., Lyssenko, Valeriya, Meigs, James B., Barroso, Inês, Watanabe, Richard M., Ingelsson, Erik, Langenberg, Claudia, Hamsten, Anders, Florez, Jose C.
    Publicado 2011
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    Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
  9. 3449
    “…The xenografted tumor-bearing models were established by subcutaneous injection of 5 × 10(6) tumor cells into shoulder flank (U87MG, A549, HT29, and PC-3) or mammary fat pad (MDA-MB-435) of each athymic nude mouse. …”
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    FITC-Conjugated Cyclic RGD Peptides as Fluorescent Probes for Staining Integrin α(v)β(3)/α(v)β(5) in Tumor Tissues
  10. 3450
    “…The bacilloscopic index at diagnosis was similar (medians: 3.6 in the R-MDT and 3.8 in the U-MDT group). In R-MDT and U-MDT groups, a significant decline in anti-PGL-I positivity was observed from M0 to M5 (p = 0.035, p = 0.04, respectively), from M6 to M12 and at the first and second year posttreatment (p < 0.05). …”
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    Mycobacterium leprae-Specific Antibodies in Multibacillary Leprosy Patients Decrease During and After Treatment With Either the Regular 12 Doses Multidrug Therapy (MDT) or the Uniform 6 Doses MDT
  11. 3451
    por Thomas, H. J. D., Myers‐Smith, I. H., Bjorkman, A. D., Elmendorf, S. C., Blok, D., Cornelissen, J. H. C., Forbes, B. C., Hollister, R. D., Normand, S., Prevéy, J. S., Rixen, C., Schaepman‐Strub, G., Wilmking, M., Wipf, S., Cornwell, W. K., Kattge, J., Goetz, S. J., Guay, K. C., Alatalo, J. M., Anadon‐Rosell, A., Angers‐Blondin, S., Berner, L. T., Björk, R. G., Buchwal, A., Buras, A., Carbognani, M., Christie, K., Siegwart Collier, L., Cooper, E. J., Eskelinen, A., Frei, E. R., Grau, O., Grogan, P., Hallinger, M., Heijmans, M. M. P. D., Hermanutz, L., Hudson, J. M. G., Hülber, K., Iturrate‐Garcia, M., Iversen, C. M., Jaroszynska, F., Johnstone, J. F., Kaarlejärvi, E., Kulonen, A., Lamarque, L. J., Lévesque, E., Little, C. J., Michelsen, A., Milbau, A., Nabe‐Nielsen, J., Nielsen, S. S., Ninot, J. M., Oberbauer, S. F., Olofsson, J., Onipchenko, V. G., Petraglia, A., Rumpf, S. B., Semenchuk, P. R., Soudzilovskaia, N. A., Spasojevic, M. J., Speed, J. D. M., Tape, K. D., te Beest, M., Tomaselli, M., Trant, A., Treier, U. A., Venn, S., Vowles, T., Weijers, S., Zamin, T., Atkin, O. K., Bahn, M., Blonder, B., Campetella, G., Cerabolini, B. E. L., Chapin III, F. S., Dainese, M., de Vries, F. T., Díaz, S., Green, W., Jackson, R. B., Manning, P., Niinemets, Ü., Ozinga, W. A., Peñuelas, J., Reich, P. B., Schamp, B., Sheremetev, S., van Bodegom, P. M.
    Publicado 2018
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    Traditional plant functional groups explain variation in economic but not size‐related traits across the tundra biome
  12. 3452
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    Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, and/or PTEN loss/PTEN mutation
  13. 3453
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    Annual Report to the Nation on the Status of Cancer, Featuring Cancer in Men and Women Age 20–49 Years
  14. 3454
    “…A 4.0 kb FAT1-promoter-construct [− 3220 bp/+ 848 bp, transcription start site (TSS) + 1, having 17 NFкB (RelA) motifs] showed high FAT1 promoter luciferase-activity in GBM cells (U87MG/A172/U373MG). FAT1 promoter deletion-construct pGL3F1 [− 200 bp/+ 848 bp, with 3-NFкB (RelA)-motifs] showed the highest promoter activity. …”
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    NFкB is a critical transcriptional regulator of atypical cadherin FAT1 in glioma
  15. 3455
    “…We leveraged pathologist annotations to develop complementary deep learning-based methods: (1) ColorAE is a deep autoencoder which segments stained objects based on color; (2) U-Net is a convolutional neural network (CNN) trained to segment cells based on color, texture and shape; and (3) ensemble methods that employ both ColorAE and U-Net, collectively referred to as ColorAE:U-Net. …”
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    Deep learning-based image analysis methods for brightfield-acquired multiplex immunohistochemistry images
  16. 3456
    “…Despite T4 substitution, TSH rose progressively (towards 51 mU/L), with a further decline in free T4 (8,7 pmol/l). …”
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    Hypothyroidism During Immune Checkpoint Inhibitor Therapy That Is Not Responsive to Thyroxin Substitution. A Peripheral T4-T3 Conversion Block?
  17. 3457
    “…Inclusion criteria were obesity at onset, high titer of diabetes-associated autoantibodies, and insulin requirement less than 0.5 U/kg with a diabetes duration of more than 6 months. …”
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    Features of Slowly Progressive Type 1 Diabetes Mellitus in Overweight Adolescents
  18. 3458
    “…Repeat blood work-up showed an elevated TSH level (23.50 mU/L) with a low Free T4 (0.42 ng/dL) and an elevated thyroid peroxidase antibody (TPO-Ab) level (900 mU/mL), indicative of subacute thyroiditis, but without associated neck pain. …”
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    Palpitations and Fatigue Post COVID: A Harbinger of Silent Thyroiditis!
  19. 3459
    “…Intra-group differences were tested by Mann–Whitney U-tests, and a linear mixed model was used to test time and group interaction. …”
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    Effects of levosimendan on renal blood flow and glomerular filtration in patients with acute kidney injury after cardiac surgery: a double blind, randomized placebo-controlled study
  20. 3460
    “…We selected 238 NPM1(mut) patients with available NGS information on 112 genes related to blood diseases using the χ2 and Mann-Whitney U tests and a multivariable logistic model to analyze the correlation between genomic alterations and clinicopathologic parameters. …”
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    The correlation of next-generation sequencing-based genotypic profiles with clinicopathologic characteristics in NPM1-mutated acute myeloid leukemia
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