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  1. 1761
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    Replacement of cysteine at position 46 in the first cysteine-rich repeat of the LDL receptor impairs apolipoprotein recognition
  2. 1762
    “…RESULTS: The combination of TMZ and metformin showed higher cytotoxicity than single agents in U87, U251, and A172 cell lines. A combination of high-dose metformin and TMZ showed the highest apoptotic activity. …”
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    High-Dose Metformin Plus Temozolomide Shows Increased Anti-tumor Effects in Glioblastoma In Vitro and In vivo Compared with Monotherapy
  3. 1763
    “…Data were evaluated using Spearman’s correlation analysis and the Mann–Whitney U test. RESULTS: A significant correlation was observed between perceived stress and XI score (r = 0.312, p = 0.001), as well as between perceived stress and BI score (r = 0.334, p = 0.001). …”
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    Relationship among perceived stress, xerostomia, and salivary flow rate in patients visiting a saliva clinic
  4. 1764
    “…Cytological experiments revealed that BPTF overexpression could significantly promote the proliferation, migration and invasion of human glioma U251 cells. A study of the underlying mechanism indicated that BPTF promoted glioma progression via MYC signaling. …”
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    Bromodomain PHD-finger transcription factor promotes glioma progression and indicates poor prognosis
  5. 1765
    “…Family‐level species richness is unrelated to phylogenetic structure, whereas species richness in tribe Theeae was related to phylogenetic structure with U‐shaped relationship, a more complex relation than predicted by the time‐for‐speciation or diversification rate hypotheses. …”
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    Environmental and evolutionary drivers of diversity patterns in the tea family (Theaceae s.s.) across China
  6. 1766
    “…The enrolled girls had a peak LH level >5.0 U/L after a gonadorelin stimulation test. Selected girls were classified as normoweight (body mass index [BMI] below the 85th percentile with respect to age) and overweight (BMI greater than the 85th percentile with respect to age). …”
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    The effect of overweight on the luteinizing hormone level after gonadorelin stimulation test in girls with idiopathic central precocious puberty
  7. 1767
    “…Cramer’s V showed significant associations were only of note (above 0.1) for age, ethnicity in the U.K. as a whole and ethnicity in England. Older (70+) and younger people (0–14) were underrepresented and those of White Ethnicity overrepresented on the NHS ODR. …”
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    Who’s opting-in? A demographic analysis of the U.K. NHS Organ Donor Register
  8. 1768
    “…METHODS: In the present study we investigated the expression of Dkk-3, claudin-5, apoptosis markers and TLR-4 receptor protein levels in in vitro studies on U-138MG, A-172, LN-18 and LN-229 human glioblastoma cell lines, and in vivo study using TLR-4 KO mice and in glioblastoma human patient’s tissues.…”
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    TLR-4/Wnt modulation as new therapeutic strategy in the treatment of glioblastomas
  9. 1769
    “…Our results confirmed the feasibility of U. tomentosa as a suitable raw material for obtaining phenolic- and alkaloid-rich extracts of potential interest.…”
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    Phenolic Assesment of Uncaria tomentosa L. (Cat’s Claw): Leaves, Stem, Bark and Wood Extracts
  10. 1770
    “…MATERIALS AND METHODS: Patients aged 18-38 years who had a normal uterine cavity, at least one normal fallopian tube, and regular menses and were unable to conceive despite unprotected intercourse for at least 12 months were randomized to receive CC alone, uFSH alone, or sequential CC and uFSH before a single IUI. The primary outcomes were clinical pregnancy and live birth rates. …”
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    Use of clomiphene citrate alone, urinary follicle-stimulating hormone alone, or both combined sequentially in patients with unexplained subfertility undergoing intrauterine insemination: A randomized trial
  11. 1771
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    Potent Antitrypanosomal Activities of 3-Aminosteroids against African Trypanosomes: Investigation of Cellular Effects and of Cross-Resistance with Existing Drugs
  12. 1772
    “…In the present study, the expression profile of miRNAs was examined in seven pGBMs and three human GBM cell lines (U87MG, A172 and T98G), compared with a non-tumoral pool of pediatric cerebral cortex samples by microarray analysis. …”
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    A microRNA profile of pediatric glioblastoma: The role of NUCKS1 upregulation
  13. 1773
    “…A specialized deep learning method—the U-net—is a promising alternative. Using labeled data from 66 patients with cerebrovascular disease, the U-net framework was optimized and evaluated with three metrics: Dice coefficient, 95% Hausdorff distance (95HD) and average Hausdorff distance (AVD). …”
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    A U-Net Deep Learning Framework for High Performance Vessel Segmentation in Patients With Cerebrovascular Disease
  14. 1774
    “…We undertook the characterization of HslV from Leishmania major (LmHslV), a trypanosomatid that expresses two isoforms for HslU, LmHslU1 and LmHslU2. Using a novel and sensitive peptide substrate, we found that LmHslV can be activated by peptides derived from the C-termini of both LmHslU1 and LmHslU2. …”
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    The HslV Protease from Leishmania major and Its Activation by C-terminal HslU Peptides
  15. 1775
    “…Motif analysis of the top 50 sequences provided a highly conserved sequence: 5′-A[A/C][C/G][G/U][U/A]ACAGAGGG[U/A]GG[A/C] GAGUGGGU-3′. APT1, APT2, and APT5 embracing this motif generated secondary structures with similar topological characteristics. …”
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    Isolation of MLL1 Inhibitory RNA Aptamers
  16. 1776
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    Human cytomegalovirus haplotype reconstruction reveals high diversity due to superinfection and evidence of within-host recombination
  17. 1777
    “…A., Palmquist, A., Wikström, P., Windahl, S. H., Lerner, U. H. Vitamin A decreases the anabolic bone response to mechanical loading by suppressing bone formation.…”
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    Vitamin A decreases the anabolic bone response to mechanical loading by suppressing bone formation
  18. 1778
    “…A detailed statistical analysis was used to correlate results (Cronbach's α coefficient, Spearman's correlation, and Mann–Whitney U-test). RESULTS: A total of 70 patients were enrolled in the study and 61 completed the final assessment. …”
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    Linguistic and cultural validation of Ureteral Stent Symptom Questionnaire in Hindi
  19. 1779
    “…We also show that this direct interaction is mediated through U1A, a core-component of U1snRNP. SAM68 was found to bind the RRM1 domain of U1A through its C-terminal tyrosine rich region (YY domain). …”
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    SAM68 interaction with U1A modulates U1 snRNP recruitment and regulates mTor pre-mRNA splicing
  20. 1780
    “…The results will better our understanding of the molecular mechanism of chlamydospore formation in U. virens as a model fungus.…”
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    A Homeobox Transcription Factor UvHOX2 Regulates Chlamydospore Formation, Conidiogenesis, and Pathogenicity in Ustilaginoidea virens
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