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221por Wang, Minhui, Ma, Tianling, Wang, Haixia, Liu, Jianzhao, Chen, Yun, Shim, Won Bo, Ma, Zhonghua“…FgRbp1 binds to the motif CAAGR in its target mRNAs, and interacts with the splicing factor FgU2AF23, a highly conserved protein involved in 3’ splice site recognition, leading to enhanced recruitment of FgU2AF23 to the target mRNAs. …”
Publicado 2021
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223por Poradowski, Dominik, Janus, Izabela, Chrószcz, Aleksander, Obmińska-Mrukowicz, Bożena“…ABSTRACT: The study describes the cytotoxic effect against human and canine osteosarcoma (U-2 OS and D-17) cell lines induced by risedronate sodium and meloxicam per se and in combination. …”
Publicado 2021
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224por Lu, Shuai, Gao, Cong, Wang, Yongzhou, He, Yingying, Du, Junrong, Chen, Moxian, Zhao, Hua, Fang, Hui, Wang, Baohua, Cao, Yunying“…U2AF65A is a member of the U2AF65 gene family, with pivotal roles in diseases in mammals, specifically humans; however, few studies have investigated plant U2AF65A, and its specific functions are poorly understood. …”
Publicado 2021
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225“…RNA pulldown and RIP assays analyzed the interaction of ZFAS1 with U2AF2 and HMGCR in BxPC-3 cells. Finally, the impacts of U2AF2 and HMGCR on the biological behavior of BxPC-3 were observed. …”
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226por Ferrone, Christina K., McNaughton, Amy J. M., Vincelli, Felicia, Zuzarte, Philip, Lee, David, Feilotter, Harriet E., Rauh, Michael J.Enlace del recurso
Publicado 2022
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229por Nikopaschou, Martha S, Félix, Alexandre, Mollergues, Julie, Scholz, Gabriele, Schilter, Benoit, Marin-Kuan, Maricel, Fussell, Karma CEnlace del recurso
Publicado 2023
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230por SI, HAIPENG, PENG, CHANGLIANG, LI, JINGJING, WANG, XIQIAN, ZHAI, LIANWEN, LI, XIAOFENG, LI, JIANMIN“…This study aimed to investigate whether downregulation of ERK1/2 by siRNA (small interfering RNA) could inhibit cell proliferation and invasion and increase chemosensitivity to cisplatin in human osteosarcoma U2-OS cells in vitro. Results showed that the downregulation of ERK1/2 expression by siRNA in human osteosarcoma cells significantly inhibited cell proliferation and invasion in vitro. …”
Publicado 2011
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231por ZHAO, SONG, NIU, FENG, XU, CHANG-YAN, YE, LONG, BI, GUI-BIN, CHEN, LIN, GONG, PING, TIAN, GANG, NIE, TIAN-HONG“…Integrative analysis of chromatin immunoprecipitation-sequencing (ChIP-seq) data and microarray data was performed to illustrate the effect of Nutlin-3 on promoter selectivity and transcriptional regulation by the tumor suppressor p53 in U2OS human osteosarcoma cells. Raw data (accession number, GSE46642) were downloaded from Gene Expression Omnibus. …”
Publicado 2015
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232por Whisenant, Thomas C., Peralta, Eigen R., Aarreberg, Lauren D., Gao, Nina J., Head, Steven R., Ordoukhanian, Phillip, Williamson, Jamie R., Salomon, Daniel R.“…In parallel, mass spectrometry revealed the proteins incorporated into the U2AF2-centered RNA/protein interactome. Molecules that retained interaction with the U2AF2 complex after RNAse treatment were designated as “central” interactome members (CIMs). …”
Publicado 2015
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233“…The brightest signals on pair 13 are coincident with the single U2 snRNA gene cluster signals. Therefore, the use of these probes allows the unequivocal identification of at least 7 of the chromosome pairs that compose the karyotype of Merluccius merluccius thus opening the way to integrate molecular genetics and cytological data on the study of the genome of this important species.…”
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234por Wang, Xiaofei, Han, Haiyan, Lv, Zhihui, Lin, Zhiwei, Shang, Yongpeng, Xu, Tao, Wu, Yang, Zhang, Ying, Qu, Di“…We separately constructed ΔphoU1 and ΔphoU2 mutants of S. epidermidis strain 1457. The ΔphoU2 mutant displayed growth retardation, a weakened biofilm formation capacity, a higher sensitivity to H(2)O(2), and reduced tolerance to multiple antibiotics. …”
Publicado 2017
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235por Kim, Suyeon, Park, Charny, Jun, Yukyung, Lee, Sanghyuk, Jung, Yeonjoo, Kim, Jaesang“…Our study thus points to an active role of U2AF1 S34F mutant protein in inducing cell cycle dysregulation and mitotic stress. …”
Publicado 2018
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236por Cavalcante, Manoella Gemaque, Nagamachi, Cleusa Yoshiko, Pieczarka, Julio Cesar, Noronha, Renata Coelho Rodrigues“…We observe high conservation of the co-located 5S rDNA and U2 snRNA genes on a small chromosome pair (pair 13), and surmise that this represents the ancestral condition. …”
Publicado 2020
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237por Dellal, Hadjer, Boulahtouf, Abdelhay, Alaterre, Elina, Cuenant, Alice, Grimaldi, Marina, Bourguet, William, Gongora, Céline, Balaguer, Patrick, Pourquier, Philippe“…In our study, we used the U2OS osteosarcoma cells stably transfected with AR or ARv7 and a luciferase reporter as a previously validated model to screen the Prestwick Phytochemical library. …”
Publicado 2020
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238por Li, Xiangde, Liu, Yun, Liao, Shijie, Lin, Chengsen, Moro, Abu, Liu, Jing, Feng, Wenyu, Wang, Kun, Wang, Chunming“…The present study also demonstrated that Polyphyllin VII upregulated the intracellular hydrogen peroxide (H(2)O(2)) levels in U2OS cells. However, treatment of U2OS cells with N-acetyl-L cysteine (NAC) effectively reversed this effect. …”
Publicado 2021
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239por Ogawa, Tetsuya, Sasaki, Ayako, Ono, Koki, Ohshika, Shusa, Ishibashi, Yasuyuki, Yamada, Katsuya“…Here we demonstrate that human osteosarcoma U2OS cells take in 2-NBDLG in a phloretin-inhibitable manner. …”
Publicado 2021
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240por Kim, Sanghyun P., Srivatsan, Sridhar N., Chavez, Monique, Shirai, Cara L., White, Brian S., Ahmed, Tanzir, Alberti, Michael O., Shao, Jin, Nunley, Ryan, White, Lynn S., Bednarski, Jeff, Pehrson, John R., Walter, Matthew J.“…Expression of the mutant splicing factor U2AF1(S34F) alters hematopoiesis and mRNA splicing in mice. …”
Publicado 2021
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