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  1. 281
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    Retraction Note: AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing
  2. 282
    “…Depletion of TDP-43, in contrast, shifted the localization of these C/D scaRNAs, mainly into the nucleolus, as well as destabilizing scaRNA2, and reduced the site-specific 2′-O-methylation of U1 and U2 snRNAs, including at 70A in U1 snRNA and, 19G, 25G, 47U and 61C in U2 snRNA. …”
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    TDP-43 regulates site-specific 2′-O-methylation of U1 and U2 snRNAs via controlling the Cajal body localization of a subset of C/D scaRNAs
  3. 283
    “…We present here a very rare case with PMF and PNH with JAK2 V617F, U2AF1 and SETBP1 mutations at the time of diagnosis. …”
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    Coexistence of Primary Myelofibrosis and Paroxysmal Nocturnal Hemoglobinuria Clone with JAK2 V617F, U2AF1 and SETBP1 Mutations: A Case Report and Brief Review of Literature
  4. 284
    “…Recent work has identified cancer-associated U2AF35 missense mutations in two zinc-finger (ZnF) domains, but little is known about Q157R/P substitutions within the second ZnF. …”
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    The cancer-associated U2AF35 470A>G (Q157R) mutation creates an in-frame alternative 5′ splice site that impacts splicing regulation in Q157R patients
  5. 285
    “…To investigate the role of the RING domain of Mdm2 and MdmX, an analysis of the distinct functionalities of individual RING domains of the Mdm proteins on p53 regulation was conducted in human osteosarcoma (U2OS) cell line. Mdm2 RING domain was observed mainly localized in the cell nucleus, contrasting the localization of MdmX RING domain in the cytoplasm. …”
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    Mdm2 and MdmX RING Domains Play Distinct Roles in the Regulation of p53 Responses: A Comparative Study of Mdm2 and MdmX RING Domains in U2OS Cells
  6. 286
    “…L48H37 decreased the phosphorylation of STAT3, JAK1, JAK2, and JAK3 in U2OS cells, but did not affect the phosphorylation of ERK, JNK, p38, and Akt. …”
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    Curcumin Analogue L48H37 Suppresses Human Osteosarcoma U2OS and MG-63 Cells’ Migration and Invasion in Culture by Inhibition of uPA via the JAK/STAT Signaling Pathway
  7. 287
    “…Our results evidenced novel hnRNP H and U2AF65 functions: respectively, U2AF65-recruiting to a 5'ss in humans and the hnRNP H-displacing function from two juxtaposed GGGG codes.…”
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    Binding of hnRNP H and U2AF65 to Respective G-codes and a Poly-Uridine Tract Collaborate in the N50-5'ss Selection of the REST N Exon in H69 Cells
  8. 288
    “…The first stable complex formed during the assembly of spliceosomes onto pre-mRNA substrates in mammals includes U1 snRNP, which recognizes the 5′ splice site, and the splicing factors SF1 and U2AF, which bind the branch point sequence, polypyrimidine tract, and 3′ splice site. …”
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    Prp40 pre-mRNA processing factor 40 homolog B (PRPF40B) associates with SF1 and U2AF(65) and modulates alternative pre-mRNA splicing in vivo
  9. 289
    “…The second intron did not splice out in a U2 dependent manner and EVA1A mRNA is not exported. …”
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    Myc/Max dependent intronic long antisense noncoding RNA, EVA1A-AS, suppresses the expression of Myc/Max dependent anti-proliferating gene EVA1A in a U2 dependent manner
  10. 290
    por Fang, Li, Ye, Ting, An, Yanmei
    Publicado 2021
    “…Next, our experiments found that circFOXP1 upregulated U2AF2 expression via sponging miR-423-5p in RCC cells. …”
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    Circular RNA FOXP1 Induced by ZNF263 Upregulates U2AF2 Expression to Accelerate Renal Cell Carcinoma Tumorigenesis and Warburg Effect through Sponging miR-423-5p
  11. 291
    “…The dysregulation of U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2) is associated with malignant behaviors of multiple types of tumors. …”
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    U2 small nuclear RNA auxiliary factor 2, transcriptionally activated by the transcription factor Dp-1/E2F transcription factor 1 complex, enhances the growth and aerobic glycolysis of leiomyosarcoma cells
  12. 292
    “…A comparison of the B(act) crosslinking pattern versus that of B* and C complexes revealed that U2 and RES protein interactions with the intron are dynamic. …”
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    Dynamic Contacts of U2, RES, Cwc25, Prp8 and Prp45 Proteins with the Pre-mRNA Branch-Site and 3' Splice Site during Catalytic Activation and Step 1 Catalysis in Yeast Spliceosomes
  13. 293
    “…For the first time, an actinide nitride clusterfullerene, U(2)N@I(h)(7)-C(80), is synthesized and fully characterized by X-ray single crystallography and multiple spectroscopic methods. …”
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    U(2)N@I(h)(7)-C(80): fullerene cage encapsulating an unsymmetrical U(iv)[double bond, length as m-dash]N[double bond, length as m-dash]U(v) cluster
  14. 294
    por Schwer, Beate, Shuman, Stewart
    Publicado 2015
    “…All three RNA site mutations of SmD3 were lethal in cells lacking the U2 snRNP subunit Lea1. Benign C-terminal truncations of SmD3 were dead in the absence of Mud2 or Lea1 and barely viable in the absence of Nam8 or Mud1. …”
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    Structure–function analysis and genetic interactions of the Yhc1, SmD3, SmB, and Snp1 subunits of yeast U1 snRNP and genetic interactions of SmD3 with U2 snRNP subunit Lea1
  15. 295
    Publicado 2017
    “…METHODS: Mutational analysis of splicing factor 3B subunit 1 (SF3B1) (K700E), U2 small nuclear RNA auxiliary factor 1 (U2AF1) (S34, Q157P) and serine/arginine-rich splicing factor 2 (SRSF2) (P95) in 118, de novo MDS and related diseases were separately performed by using polymerase chain reaction (PCR) followed by sequence analysis. …”
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    118例骨髓增生异常综合征及相关疾病患者RNA剪接体复合物蛋白编码基因SF3B1、U2AF1和SRSF2突变分析
  16. 296
    Publicado 2022
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    Teilnahme am Regelunterricht (Präsenzunterricht) in der Schule ohne Mund-Nasen-Bedeckung: GG Art. 2 Abs. 1 u. 2, 19 Abs. 4; VwGO 80 Abs. 5,123 Abs. 1 S. 2; ZPO 920 Abs. 2 ZPO, 294; IfSG 32 S. 1 u. 2, 28a Abs. 1 S. 1; Nds. Corona-Verordnung 3 Abs. 6, 13 Abs. 1 S. 4ff.; NSchG 31 Abs. 1, Abs. 10 Nr. 1 lit. h).
  17. 297
    por Campos Cruz, Rosario
    Publicado 2015
    Tesis Libro
    Limpiezas químicas como medidas preventivo correctivas en las fallas de los generadores de vapor de alta presión U2 del complejo termoeléctrico presidente adolfo lópez mateos, de la ciudad de tuxpan, ver. méxico. : /
  18. 298
    por Laslett, L J
    Publicado 1959
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    Concerning the $\nu/N \to {1/3}$ resonance, IV : the limiting-amplitude solution of the equation $\frac {d^{2}u}{d\phi^{2}} + {(a+b\cos2\phi)u} + {\frac{B_{1}}{2}}{(\sin2\phi)}u^2=0$
  19. 299
    por Laslett, L J
    Publicado 1959
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    Concerning the $\nu/N \to {1/3}$ resonance, IV : a trial function for the limiting-amplitude solution of $\frac {d^{2}u}{d\phi^{2}} + {(a+b\cos2\phi)u} + {\frac{B_{1}}{2}}{(\sin2\phi)}u^2=0$
  20. 300
    “…This study aimed to investigate the effects of ALS on the cell growth, apoptosis, autophagy, and epithelial to mesenchymal transition (EMT) and the underlying mechanisms in two human OS cell lines U-2 OS and MG-63. The results showed that ALS had potent growth inhibitory, pro-apoptotic, pro-autophagic, and EMT inhibitory effects on U-2 OS and MG-63 cells. …”
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    Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway
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