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441“…Instead, this strain accumulates free U4 snRNP, protein-free U6 RNA, and a novel complex containing U2/U6 di-snRNP. Further mutational analysis indicates that disruption of the U6–Prp24 interaction rather than stabilization of U2/U6 renders stable U4/U6 di-snRNP assembly nonessential. …”
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442por Zhao, Bingran, van der Mei, Henny C, Rustema-Abbing, Minie, Busscher, Henk J, Ren, Yijin“…Monoculture studies with either U2OS osteoblasts or bacteria were also carried out and indicated significant differences in biofilm formation between the implant materials, but interactions with U2OS osteoblasts were favourable on all materials. …”
Publicado 2015
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443por Koo, Hyunmin, Mojib, Nazia, Hakim, Joseph A., Hawes, Ian, Tanabe, Yukiko, Andersen, Dale T., Bej, Asim K.“…The functional predictions of the microbial communities in U2 and U3 represented signal transduction, membrane transport, zinc transport and amino acid-, carbohydrate-, and arsenic- metabolisms. …”
Publicado 2017
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444por Xie, Da, Zheng, Gui-Zhou, Xie, Peng, Zhang, Qi-Hao, Lin, Fei-Xiang, Chang, Bo, Hu, Qin-Xiao, Du, Shi-Xin, Li, Xue-Dong“…Moreover, Cx43 expression is negatively related to the activity of the Wnt/β-catenin pathway in U2-OS cells.…”
Publicado 2017
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445“…Cell viability, colony formation, and cell migration were measured in MG-63, U2OS and hFOB 1.19 cells, which were transfected with miR-1284 mimics or miR-NC. …”
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446por Skalniak, Lukasz, Kocik, Justyna, Polak, Justyna, Skalniak, Anna, Rak, Monika, Wolnicka-Glubisz, Agnieszka, Holak, Tad A.“…Moreover, idasanutlin-treated U-2 OS cells could be cultured for long time periods in the presence of the drug. …”
Publicado 2018
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447“…METHODS: ANCR expression was determined in OS tissues and OS cell lines (MG-63, S1353, U2OS, and UMR-106) by qRT-PCR. It was observed that ANCR was down-regulated in MG-63 and U2OS cells by 48 h of siRNA-ANCR (si-ANCR) transfection. …”
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448“…MTT assay was adopted to detect the effects of microRNA-664-3p on the proliferation of U2-OS after 24, 48, 72, 96 and 120 hours of transfection. …”
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449por Sapio, Luigi, Nigro, Ersilia, Ragone, Angela, Salzillo, Alessia, Illiano, Michela, Spina, Annamaria, Polito, Rita, Daniele, Aurora, Naviglio, Silvio“…The investigation of the molecular mechanisms highlights a common and initial ERK1/2 activation in response to AdipoR in both Saos-2 and U2OS cells. Interestingly, a simultaneous and dramatic downregulation of p70S6K phosphorylation, one of the main targets of mTORC1 pathway, has also been observed in AdipoR-treated Saos-2, but not in U2OS cells. …”
Publicado 2020
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450“…U1 exhibited translation movement, while U(2) underwent less tipping during 0.2 mm retraction and 0.15 mm intrusion. …”
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451por Jagtap, Pravin Kumar Ankush, Kubelka, Tomáš, Soni, Komal, Will, Cindy L., Garg, Divita, Sippel, Claudia, Kapp, Tobias G., Potukuchi, Harish Kumar, Schorpp, Kenji, Hadian, Kamyar, Kessler, Horst, Lührmann, Reinhard, Hausch, Felix, Bach, Thorsten, Sattler, Michael“…Interactions between U2AF homology motifs (UHMs) and U2AF ligand motifs (ULMs) play a crucial role in early spliceosome assembly in eukaryotic gene regulation. …”
Publicado 2020
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452“…The results showed that miR-107 expression was upregulated in osteosarcoma tissues and cell lines. miR-107 overexpression promoted U2OS cell viability, migration, and invasion whereas it inhibited apoptosis. miR-107 inhibitor transfection ameliorated or abolished these effects after miR-107 binding to TPM1 3′-UTR-wt regulated TPM1 expression. miR-107 in U2OS cells activated MEK/ERK and NF-κB signaling pathways via TPM1. …”
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453“…METHODS: A total of 350 U2plus users participated in a web-based survey. …”
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454“…Both HUVECs supernatant and HUVECs-exosomes promoted the sarcosphere formation efficiency of U2OS and 143B cells. These stem-like phenotypes of U2OS and 143B cells conferred by HUVECs-exosomes were repressed by GW4869. …”
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455por Oh, Jisun, An, Hyun−Ju, Yeo, Hyun Jeong, Choi, Sujin, Oh, Jisu, Kim, Segi, Kim, Jin Man, Choi, Junwon, Lee, Soonchul“…RESULTS: Colchicine was selected as the lead compound based on the results of initial screening and cell viability assays conducted in Saos-2 and U2Os cells. Colchicine reduced the viability of Saos-2 and U2OS cells in a concentration-dependent manner. …”
Publicado 2022
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456por Ward, Robert J., del Rosal, Iker, Kelley, Steven P., Maron, Laurent, Walensky, Justin R.“…For example, addition of more CO to the ethynediolate complex with heating forms a ketene carboxylate, [{(C(5)Me(5))(2)(MesO)U}(2)(μ(2):κ(2):η(1)-C(3)O(3))], which can be further reacted with CO(2) to yield a ketene dicarboxylate complex, [{(C(5)Me(5))(2)(MesO)U}(2)(μ(2):κ(2):κ(2)-C(4)O(5))]. …”
Publicado 2023
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457“…Static CP^1 and scattering U(2) solitons are constructed and carry an additional spin-1/2 degree of freedom due to the deformation. …”
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458“…The transition amplitude is proportional to the mass ratio (m_d^2-m_u^2)/(m_s^2-m^2). The factor of proportionality is calculated by means of dispersion relations, using chiral perturbation theory to determine the subtraction constants. …”
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459por Sheth, Nihar, Roca, Xavier, Hastings, Michelle L., Roeder, Ted, Krainer, Adrian R., Sachidanandam, Ravi“…We have collected over half a million splice sites from five species—Homo sapiens, Mus musculus, Drosophila melanogaster, Caenorhabditis elegans and Arabidopsis thaliana—and classified them into four subtypes: U2-type GT–AG and GC–AG and U12-type GT–AG and AT–AC. …”
Publicado 2006
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460por Dundr, Miroslav, Ospina, Jason K., Sung, Myong-Hee, John, Sam, Upender, Madhvi, Ried, Thomas, Hager, Gordon L., Matera, A. Gregory“…In this study, we present an experimental system to probe the dynamic interplay of CBs with a U2 snRNA target gene locus during transcriptional activation in living cells. …”
Publicado 2007
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