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Mostrando 521 - 540 Resultados de 2,310 Para Buscar '"U2"', tiempo de consulta: 0.54s Limitar resultados
  1. 521
    “…RESULTS: Knockdown of USP39 expression in U2OS cell significantly decreased cell proliferation, impaired colony formation ability. …”
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    Knockdown of ubiquitin-specific peptidase 39 inhibited the growth of osteosarcoma cells and induced apoptosis in vitro
  2. 522
    “…SF3b1 plays a key role in recruiting the U2 snRNP to the BS. Mutations in human SF3b1 have been linked to many diseases such as myelodysplasia (MDS) and cancer. …”
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    SF3b1 mutations associated with myelodysplastic syndromes alter the fidelity of branchsite selection in yeast
  3. 523
    “…Cell cycle arrest at G(2)/M was observed in U-2 OS and Saos-2. Cell differentiation was most prominent in MG-63 and U-2 OS as determined by increases in the terminal differentiation markers osteopontin and collagen 1a1. …”
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    Polyamine Biosynthetic Pathway as a Drug Target for Osteosarcoma Therapy
  4. 524
    “…In the present study, reverse transcription-quantitative polymerase chain reaction data demonstrated that XIST was significantly upregulated in OS tissues and cell lines (Saos-2, U2OS, HOS and MG63) compared with adjacent non-tumour tissues and normal human osteoblast cell line HFOB1.19. …”
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    Long non-coding RNA XIST serves an oncogenic role in osteosarcoma by sponging miR-137
  5. 525
    “…OBJECTIVES: To compare the clinical outcome between bipolar hemiarthroplasty (BHA) and total hip arthroplasty (THA) using a U2 HA cementless hip stem, and the results of elderly femoral neck fracture patients who underwent BHA with a cementless hip stem. …”
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    Comparison of Mid‐term Survivorship and Clinical Outcomes between Bipolar Hemiarthroplasty and Total Hip Arthroplasty with Cementless Stem: A Multicenter Retrospective Study
  6. 526
    “…We further demonstrate that Ψ strengthens U4/U6 RNA–RNA and U2B"/U2A’ proteins-U2 snRNA interaction at elevated temperatures. …”
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    Pseudouridines on Trypanosoma brucei spliceosomal small nuclear RNAs and their implication for RNA and protein interactions
  7. 527
    “…Prp5 is essential for stable association of the U2 snRNP with the intron branch site (BS) sequence during spliceosome assembly. …”
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    Dynamics of the DEAD-box ATPase Prp5 RecA-like domains provide a conformational switch during spliceosome assembly
  8. 528
    “…We found that PTBP1 was significantly increased in chemotherapeutically insensitive osteosarcoma tissues and cisplatin‐resistant osteosarcoma cell lines (MG‐63(CISR) and U‐2OS(CISR)) as compared to chemotherapy‐sensitive osteosarcoma tissues and cell lines. …”
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    PTBP1 modulates osteosarcoma chemoresistance to cisplatin by regulating the expression of the copper transporter SLC31A1
  9. 529
    “…We included 104 Legion Prosthesis, 76 U2 Knee Prosthesis, 46 NexGen LPS-Flex Prosthesis, and 21 Vanguard Knee System products. …”
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    Effects of different prosthetic instrumentations on tibial bone resection in total knee arthroplasty
  10. 530
    “…The degradation and ubiquitination of protein arginine N‐methyltransferase 1 (PRMT1) were obviously enhanced in U‐2 OS cells with CHIP overexpression and GGA treatment. …”
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    Geranylgeranylacetone promotes human osteosarcoma cell apoptosis by inducing the degradation of PRMT1 through the E3 ubiquitin ligase CHIP
  11. 531
    “…Thus, the universal primers for region U2 could be used to analyze soil nematode communities. …”
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    Use of universal primers for the 18S ribosomal RNA gene and whole soil DNAs to reveal the taxonomic structures of soil nematodes by high-throughput amplicon sequencing
  12. 532
    “…The assays of homologous recombination repair, mitomycin C (MMC) sensitivity, immunofluorescence, and ubiquitination modification were performed in U2OS and DR-U2OS cell lines. In MMC-treated U2OS cells, the downregulation of the DNAH2 gene increased the sensitivity of cells to DNA inter-strand crosslinks. …”
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    DNAH2 facilitates the homologous recombination repair of Fanconi anemia pathway through modulating FANCD2 ubiquitination
  13. 533
    “…MYC overexpression in U2OS cells modulated histone acetylation and increased MYC binding at super-enhancers. …”
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    MYC overexpression leads to increased chromatin interactions at super-enhancers and MYC binding sites
  14. 534
    por Liang, Li-Yan, Li, Gui-Shi
    Publicado 2022
    “…In addition, KIFC1 shRNA could effectively silence KIFC1 expression in MG-63 and U-2 OS cells. Furthermore, the knockdown of KIFC1 inhibited the cell proliferation ability with increased cell apoptosis in MG-63 and U-2 OS cells. …”
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    The Roles of KIFC1 in the Development of Osteosarcoma: Characterization of Potential Therapeutic Targets
  15. 535
    por Liu, Qi, Lin, Feng
    Publicado 2022
    “…The results of RT-qPCR and western blotting showed that the expression of IARS2 was effectively knocked down in the MNNG/HOS and U2OS cell lines. Celigo, MTT and colony formation assays showed that IARS2 knockdown in MNNG/HOS and U2OS cell lines inhibited cell proliferation and colony formation compared with in the control group. …”
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    Lentivirus-induced knockdown of IARS2 expression inhibits the proliferation and promotes the apoptosis of human osteosarcoma cells
  16. 536
    “…First, 12 cell lines were screened for their ability to form 3D spheroids: prostate (DU145), testis (F9), embryonic fibroblast (NIH-3T3), muscle (C2C12), embryonic kidney (293T), neuroblastoma (SH-SY5Y), adenocarcinomic alveolar basal epithelial cell (A549), cervical cancer (HeLa), HeLa contaminant (HEp2), pituitary epithelial-like cell (GH3), embryonic cell (PA317), and osteosarcoma (U-2OS) cells. Of these, eight cell lines were selected: NIH-3T3, C2C12, 293T, SH-SY5Y, A549, HeLa, PA317, and U-2OS; and five underwent real-time monitoring of CDDP cytotoxicity: HeLa, A549, 293T, SH-SY5Y, and U-2OS. …”
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    Real-time monitoring of cisplatin cytotoxicity on three-dimensional spheroid tumor cells
  17. 537
    “…RESULTS/ANTICIPATED RESULTS: U2R2 identified 9370 patients from the University of Utah Hospitals and Clinics as potential matches. …”
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    2507: Towards a scalable informatics platform for enhancing accrual into clinical research studies
  18. 538
    “…The U(4+)–U(4+) nitride complexes, [NBu(4)][{(((t)BuO)(3)SiO)(3)U}(2)(μ-N)], [NBu(4)]-1, and [NBu(4)][((Me(3)Si)(2)N)(3)U}(2)(μ-N)], 2, were synthesised by reacting NBu(4)N(3) with the U(3+) complexes, [U(OSi(O(t)Bu)(3))(2)(μ-OSi(O(t)Bu)(3))](2) and [U(N(SiMe(3))(2))(3)], respectively. …”
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    Tuning the structure, reactivity and magnetic communication of nitride-bridged uranium complexes with the ancillary ligands
  19. 539
    Publicado 2021
    “…At age <60 years, no transfusion dependence of RBC and wild-type U2AF1 mutation is a favorable prognostic factor.…”
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    环孢素A联合达那唑±沙利度胺治疗原始细胞不增高骨髓增生异常综合征的疗效及其影响因素分析
  20. 540
    “…Ultimately, luciferase reporter gene assays and ChIP assays confirmed that FOXC1 suppressed transcription of U2AF2 by binding to the U2AF2 promoter in the –400 bp to –100 bp region.　 …”
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    A novel tumour suppressor protein encoded by circMAPK14 inhibits progression and metastasis of colorectal cancer by competitively binding to MKK6
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