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Mostrando 721 - 740 Resultados de 2,310 Para Buscar '"U2"', tiempo de consulta: 0.48s Limitar resultados
  1. 721
    “…The structure of the human B(act) complex contains 52 proteins, U2, U5, and U6 small nuclear RNA (snRNA), and a pre-mRNA. …”
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    Structure of the human activated spliceosome in three conformational states
  2. 722
    “…Interestingly, U2-OS cells showed less expression of complement regulatory proteins, compared to other cancer cell lines. …”
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    Activation of the complement system in an osteosarcoma cell line promotes angiogenesis through enhanced production of growth factors
  3. 723
    “…We found the expression of miR-567 was significantly reduced in OS tissues and cell lines (MG-63, U2OS and Saos-2) compared with the adjacent normal tissues and normal osteoblastic cells (hFOB), respectively. …”
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    MicroRNA-567 inhibits cell proliferation, migration and invasion by targeting FGF5 in osteosarcoma
  4. 724
    “…The combination of astragaloside IV and cyclopamine reduced MG-63 and U-2OS cell proliferation and migration, and inhibited the gene expression of SHH and GLI1. …”
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    Astragaloside IV promotes the proliferation and migration of osteoblast-like cells through the hedgehog signaling pathway
  5. 725
    “…The pattern of nucleolar morphology differed between HCT116 and U2OS cells, and the p53 deficiency altered the pattern of nucleolar morphology. …”
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    p53 deficiency augments nucleolar instability after ionizing irradiation
  6. 726
    por Ren, Xiaojun, Su, Chunhong
    Publicado 2020
    “…SphK1 expression levels in OS cell lines (U2OS, MG63 and SaoS2) were analyzed using western blotting and reverse transcription-quantitative PCR (RT-qPCR). …”
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    Sphingosine kinase 1 contributes to doxorubicin resistance and glycolysis in osteosarcoma
  7. 727
    “…In terms of possible mechanisms, we found that simvastatin did not alter the expression of hepatic circadian clock gene in vivo, although it failed to change the period, phase and amplitude of oscillation patterns in Per2::Luc U2OS and Bmal1::Luc U2OS cells in vitro. In contrast, simvastatin regulated the expression of Hmgcr, Mdr1 and Slco2b1 in a circadian manner, which potentially contributed to the chronopharmacological function of the drug. …”
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    Chronopharmacology of simvastatin on hyperlipidaemia in high‐fat diet‐fed obese mice
  8. 728
    “…The expression of LRRC8A in the nuclei and cytoplasm of U2OS tumor cells and MC3T3-E1 osteoblast-like cells was determined using reverse transcription-quantitative PCR. …”
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    Expression of LRRC8A is elevated in the cytoplasm of osteosarcoma tissues: An immunohistochemical study with tissue microarrays
  9. 729
    “…The interaction between KRAS-rs12427141 and HRAS-rs12628 increased the risk of PTC (U=-2.119, p<0.05), the interaction between KRAS-rs2273267 and HRAS-rs7315339 reduced the risk of PTC (U=2.195, p<0.05). …”
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    Association analysis between the interaction of RAS family genes mutations and papillary thyroid carcinoma in the Han Chinese population
  10. 730
    por Li, Tao, Li, Na, Wang, Lei, Li, Jia, Zhang, Xin
    Publicado 2021
    “…Interestingly, MPP8 knockdown via shRNA restrained the cell viability and proliferation of U2OS and Saos-2 cells. In addition, MPP8 knockdown promoted the apoptosis of U2OS and Saos-2 cells, while MPP8 overexpression promotes proliferation and inhibited the cell apoptosis of osteosarcoma cells. …”
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    MPP8 Promotes Proliferation and Restrains Apoptosis in Osteosarcoma by Regulating p38αMAPK Pathway
  11. 731
    “…A human Dox-sensitive OSA cell line, U2OS, served as the negative control. Au-GSH-Dox, compared to free Dox, presented a greater cytotoxic effect on D17 (IC(50) values for Au-GSH-Dox and Dox were 7.9 μg/mL and 15.2 μg/mL, respectively) but not on the U2OS cell line. …”
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    Enhanced Cytotoxic Effect of Doxorubicin Conjugated to Glutathione-Stabilized Gold Nanoparticles in Canine Osteosarcoma—In Vitro Studies
  12. 732
    “…The jumonji domain-containing protein 6 (JMJD6) gene catalyzes the arginine demethylation and lysine hydroxylation of histone and a growing list of its known substrate molecules, including p53 and U2AF65, suggesting a possible role in mRNA splicing and transcription in cancer progression. …”
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    Computational and Mass Spectrometry-Based Approach Identify Deleterious Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) in JMJD6
  13. 733
    “…The 18S rDNA occurs in the distal region of the short arm of pair 2; the 5S rDNA occurs in five chromosome pairs; and the U2 snDNA sequence occurs in chromosome pairs 3, 6, and 13. …”
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    Archolaemus janeae (Gymnotiformes, Teleostei): First insights into karyotype and repetitive DNA distribution in two populations of the Amazon
  14. 734
    “…Compared with free DOX under acidic conditions, the CDs-DOX complex has higher cellular uptake and better transmembrane efficacy in U(2)OS cells. Additionally, high concentrations of ATP will cause negative changes in cell membrane permeability, which will hinder the transmembrane transport of CDs and DOX and delay the rapid diffusion of CDs-DOX. …”
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    Nanodrug Transmembrane Transport Research Based on Fluorescence Correlation Spectroscopy
  15. 735
    “…Reconstruction with posterior instrumentation (PI) alone (U2L2 and U1L1+(intermediate screw) and three-column spinal reconstruction (TCSR) constructs (U1L1+PMMA and U1L1+Cage) were compared. …”
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    Optimization of Spinal Reconstructions for Thoracolumbar Burst Fractures to Prevent Proximal Junctional Complications: A Finite Element Study
  16. 736
    “…Our data showed that treating U2OS cells with doxorubicin increased P53 protein level while reducing cMYC level. …”
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    Sequence-to-expression approach to identify etiological non-coding DNA variations in P53 and cMYC-driven diseases
  17. 737
    Publicado 2023
    “…The genes with mutation frequency ≥10％ were: ASXL1（48％）, NRAS（34％）, RUNX1（33％）, TET2（28％）, U2AF1（23％）, SRSF2（21.1％）, SETBP1（20％）, KRAS（17％）, CBL（15.6％）and DNMT3A（11％）. …”
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    单中心109例慢性粒-单核细胞白血病患者的分子学特征分析
  18. 738
    “…Notch 1 expression was significantly inhibited in puPA- and pU2-treated pre-established intracranial tumors in mice. …”
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    Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptor
  19. 739
    “…METHODS: We used cell viability assays, colony formation assays, and apoptosis assays to analyze the effects of altered GSK-3β expression in U2OS, MG63, SAOS2, U2OS/MTX300, and ZOS osteosarcoma cell lines. …”
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    Glycogen Synthase Kinase-3β, NF-κB Signaling, and Tumorigenesis of Human Osteosarcoma
  20. 740
    “…The U2 snRNA sequence was the most variable of the three multigene families studied. …”
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    Evidence for 5S rDNA Horizontal Transfer in the toadfish Halobatrachus didactylus (Schneider, 1801) based on the analysis of three multigene families
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