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781por Pagotto, Sara, Veronese, Angelo, Soranno, Alessandra, Lanuti, Paola, Di Marco, Mirco, Russo, Marco Vincenzo, Ramassone, Alice, Marchisio, Marco, Simeone, Pasquale, Guanciali Franchi, Paolo E., Palka, Giandomenico, Costantini, Renato Mariani, Croce, Carlo M., Visone, Rosa“…In U2OS cells, exogenous miR-155 expression reduced the recruitment of BUB1, CENP-F, and ZW10 to the kinetochores which resulted in defective chromosome congression. …”
Publicado 2018
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782por Sun, Shiyong, Wang, Tao, Wang, Linlin, Li, Xiaoming, Jia, Yancui, Liu, Chang, Huang, Xuehui, Xie, Weibo, Wang, Xuelu“…Molecular analyses show that brassinosteroid-promoted mesocotyl elongation functions by suppressing the phosphorylation of an U-type cyclin, CYC U2, by OsGSK2. Importantly, the F-box protein D3, a major positive component in strigolactone signaling, can degrade the OsGSK2-phosphorylated CYC U2 to inhibit mesocotyl elongation. …”
Publicado 2018
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783“…In vitro, miR-184 was transfected into U-2OS cells and 143B cells. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was used to detect the expression of miR-184. …”
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784por Lima, Felipe Teixeira, Seba, Viviane, Silva, Gabriel, Torrezan, Guilherme Silva, Polaquini, Carlos Roberto, Pinhanelli, Vitor Caressato, Baek, Seung J., Fachin, Ana Lúcia, Regasini, Luis Octavio, Marins, Mozart“…The aim of this study was a preliminary evaluation of the curcumin analogue CH-5 as a cytotoxic agent in human osteosarcoma cell lines U2OS, MG-63, and Saos-2. CH-5 inhibited cell viability at lower concentrations than curcumin, leading to the induction of apoptosis. …”
Publicado 2018
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785por Parra, Marilyn, Booth, Ben W., Weiszmann, Richard, Yee, Brian, Yeo, Gene W., Brown, James B., Celniker, Susan E., Conboy, John G.“…Although many of these cryptic exons were spliced inefficiently, they exhibited substantial binding of U2AF1 and U2AF2 adjacent to their splice acceptor sites. …”
Publicado 2018
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786“…In the current study, we identified a novel circRNA, hsa_circ_0081001, screened by the RNA sequencing in the three paired chemo-resistant and chemo-sensitive OS cell lines (MG63/DXR vs MG63, KHOS/DXR vs KHOS, U2OS/DXR vs U2OS), and found that hsa_circ_0081001 was significantly up-regulated in the OS cell lines, tissues and serums, associated with poor overall survival and cox multivariate analysis showed that hsa_circ_0081001 was a novel independent prognostic factor for OS patients. …”
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787por Kruglov, Ivan A., Kvashnin, Alexander G., Goncharov, Alexander F., Oganov, Artem R., Lobanov, Sergey S., Holtgrewe, Nicholas, Jiang, Shuqing, Prakapenka, Vitali B., Greenberg, Eran, Yanilkin, Alexey V.“…Chemistry of the U-H system turned out to be extremely rich, with 14 new compounds, including hydrogen-rich UH(5), UH(6), U(2)H(13), UH(7), UH(8), U(2)H(17), and UH(9). Their crystal structures are based on either common face-centered cubic or hexagonal close-packed uranium sublattice and unusual H(8) cubic clusters. …”
Publicado 2018
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788por Liu, Ling, Pan, Jun, Wang, Huan, Ma, Zhenni, Yin, Jie, Yuan, Feng, Yuan, Quanwen, Zhou, Lu, Liu, Xiaofeng, Zhang, Yu, Bao, Zhaohua, Yang, Huilin, Ling, Jing“…Here, we reported that the expression of vWF was significantly increased, but miR-24 was significantly decreased in OS tissues (n=84). vWF was further validated as the target of miR-24 in MG-63 and U2OS cells. miR-24 obviously suppressed the proliferation and migration of MG-63 and U2OS cells. …”
Publicado 2018
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789por Gerin, Isabelle, Bury, Marina, Baldin, Francesca, Graff, Julie, Van Schaftingen, Emile, Bommer, Guido T.“…Thus, phosphoglycolate concentrations due to DNA damage are too low to cause major metabolic changes in HCT116 and U2OS cells.…”
Publicado 2019
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790por Sun, Dan, Yu, Meng, Li, Yuanyuan, Xing, Haotian, Gao, Ying, Huang, Zhihong, Hao, Wenjun, Lu, Kaining, Kong, Chuize, Shimozato, Osamu, Ozaki, Toshinori, Zhu, Yuyan“…Anti‐cancer drug adriamycin (ADR) treatment induced cell death in p53‐wild‐type human osteosarcoma U2OS cells, and this was accompanied by a remarkable accumulation of p53 and γH2AX. …”
Publicado 2019
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791por Vicentini, Rafael, Da Silva, Leonardo Morais, Cecilio Junior, Edson Pedro, Alves, Thayane Almeida, Nunes, Willian Gonçalves, Zanin, Hudson“…The standard method for determining the maximum power (P(max)) of these devices uses the relation P(max) = U(2)/4R(ESR), where U stands for the cell voltage and R(ESR) for the equivalent series resistance. …”
Publicado 2019
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792por Pervouchine, Dmitri, Popov, Yaroslav, Berry, Andy, Borsari, Beatrice, Frankish, Adam, Guigó, Roderic“…We also suggest specific splicing events that could be implicated in autoregulatory feedback loops in RBM39, HNRNPM, and U2AF2 genes. The results are available through a UCSC Genome Browser track hub.…”
Publicado 2019
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793por Zhao, Ning, Kamijo, Kouta, Fox, Philip D., Oda, Haruka, Morisaki, Tatsuya, Sato, Yuko, Kimura, Hiroshi, Stasevich, Timothy J.“…The HA frankenbody also enables state-of-the-art single-molecule experiments in living cells, which we demonstrate by tracking single HA-tagged histones in U2OS cells and single mRNA translation dynamics in both U2OS cells and neurons. …”
Publicado 2019
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794por Islam, Md. Saiful, McDonough, Michael A., Chowdhury, Rasheduzzaman, Gault, Joseph, Khan, Amjad, Pires, Elisabete, Schofield, Christopher J.“…JMJD6 is reported to catalyze hydroxylation of lysine residue(s) of histones, the tumor-suppressor protein p53, and splicing regulatory proteins, including u2 small nuclear ribonucleoprotein auxiliary factor 65-kDa subunit (U2AF65). …”
Publicado 2019
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795“…Moreover, nudol(1) caused cell cycle arrest at G2/M phase in U2OS cells, and it also induced cell apoptosis through the caspase-dependent pathway. …”
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796“…RESULTS: Overexpression of miR-596 via lentiviral particles repressed the protein level of Survivin in U2OS cells. Transfection of miR-596 enhanced the antitumor effect of anlotinib on U2OS cells or five cell lines derived from OSA patients. …”
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797“…PtNPs and DOX significantly inhibited U2OS viability and proliferation in a dose-dependent manner, increasing lactate dehydrogenase leakage, ROS generation, and malondialdehyde, nitric oxide, and carbonylated protein levels. …”
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798por Lemaire, Sébastien, Fontrodona, Nicolas, Aubé, Fabien, Claude, Jean-Baptiste, Polvèche, Hélène, Modolo, Laurent, Bourgeois, Cyril F., Mortreux, Franck, Auboeuf, Didier“…In contrast, splicing factor–dependent AT-rich exons have a large number of decoy branch points, SF1- or U2AF2-binding sites and are dependent on U2 snRNP–associated proteins. …”
Publicado 2019
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799“…The study evaluates the protective effect of mangiferin on osteosarcoma cell proliferation and metastasis. Saos-2 and U2OS cells were treated with mangiferin (25, 50, 75 and 100 µM) for 72 h. …”
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800“…RESULTS: IL-33 was upregulated in human osteosarcoma cell lines, including U2OS cells. The use of an IL-33 gene plasmid promoted osteosarcoma cell viability, inhibited cell apoptosis, increased the expression of Bcl-2, and reduced the expression of Bax. …”
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