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1141“…However, to reduce production costs due to the high implementation of prevention strategies and to maintain the disease in a controlled state, both controls u (1) and u (2) should be implemented between 40% and 60%, obtaining with this percentage an approximate reduction of 51.37% in production costs per week, where in 23 weeks following the same conditions it is expected to have a healthy plantation without infected plants.…”
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1142por Soares, Letícia Batista, Paim, Fabilene Gomes, Ramos, Lucas Peres, Foresti, Fausto, Oliveira, Claudio“…The distribution of the U snRNA genes was mapped on the Hollandichthys chromosomes for the first time, with the probes revealing the presence of the U1 snDNA on the chromosomes of pair 20, U2 on pairs 6 and 19, U4 on pair 16, and U6 on the chromosomes of pair 11. …”
Publicado 2021
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1143por Beneventi, Giulia, Munita, Roberto, Cao Thi Ngoc, Phuong, Madej, Magdalena, Cieśla, Maciej, Muthukumar, Sowndarya, Krogh, Nicolai, Nielsen, Henrik, Swaminathan, Vinay, Bellodi, Cristian“…Specifically, we find that SCARNA15 guides critical pseudouridylation (Ψ) of U2 spliceosomal RNA to fine-tune AS of distinct transcripts enriched for chromatin and transcriptional regulators in malignant cells. …”
Publicado 2021
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1144por Nonga, Olivier E., Lavogina, Darja, Enkvist, Erki, Kestav, Katrin, Chaikuad, Apirat, Dixon-Clarke, Sarah E., Bullock, Alex N., Kopanchuk, Sergei, Ivan, Taavi, Ekambaram, Ramesh, Viht, Kaido, Knapp, Stefan, Uri, Asko“…Fluorescent probes were efficiently taken up by U2OS cells and showed a high extent of co-localization with PIM-1 fused with a fluorescent protein. …”
Publicado 2021
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1145por Weißenbruch, Kai, Grewe, Justin, Hippler, Marc, Fladung, Magdalena, Tremmel, Moritz, Stricker, Kathrin, Schwarz, Ulrich Sebastian, Bastmeyer, Martin“…Mammalian cells express up to three isoforms termed NM IIA, B, and C. We used U2OS cells to create CRISPR/Cas9-based knockouts of all three isoforms and analyzed the phenotypes on homogenously coated surfaces, in collagen gels, and on micropatterned substrates. …”
Publicado 2021
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1146por Lüddecke, Tim, Paas, Anne, Talmann, Lea, Kirchhoff, Kim N., von Reumont, Björn M., Billion, André, Timm, Thomas, Lochnit, Günter, Vilcinskas, Andreas“…Here, we tested the ability of three commercially available cell-free protein expression systems to produce venom components from small arthropods, using U(2)-sicaritoxin-Sdo1a from the six-eyed sand spider Hexophtalma dolichocephala as a case study. …”
Publicado 2021
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1147por Chang, Yue, Zhao, Yulu, Wang, Liya, Wu, Meijuan, He, Chenglong, Huang, Mengxi, Lei, Zengjie, Yang, Jiahe, Han, Siqi, Wang, Bibo, Chen, Yanyan, Liu, Chao, Yu, Hongju, Xue, Lijun, Geng, Jian, Chen, Yanan, Dai, Tingting, Ren, Lili, Wang, Qian, Liu, Xiaobei, Chu, Xiaoyuan, Chen, Cheng“…Here, we demonstrated that PHF5A, a component of U2 small nuclear ribonucleoproteins, was frequently upregulated in colorectal cancer (CRC) samples and associated with poor prognosis. …”
Publicado 2021
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1148por Pietras, Paulina, Leśniczak-Staszak, Marta, Kasprzak, Aldona, Andrzejewska, Małgorzata, Jopek, Karol, Sowiński, Mateusz, Rucinski, Marcin, Lyons, Shawn M., Ivanov, Pavel, Szaflarski, Witold“…In this study, the cellular vault’s components MVP (major vault protein), TEP1 (telomerase-associated protein 1) and vPARP (vault poly(ADP-ribose) polymerase) were transiently or completely inhibited in U2OS cells (human bone osteosarcoma epithelial cells) to evaluate their impact on the cell proliferative and migratory capacity as well as on the development of their resistance to the drug vinorelbine. …”
Publicado 2021
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1149por Mangeat, Thomas, Labouesse, Simon, Allain, Marc, Negash, Awoke, Martin, Emmanuel, Guénolé, Aude, Poincloux, Renaud, Estibal, Claire, Bouissou, Anaïs, Cantaloube, Sylvain, Vega, Elodie, Li, Tong, Rouvière, Christian, Allart, Sophie, Keller, Debora, Debarnot, Valentin, Wang, Xia Bo, Michaux, Grégoire, Pinot, Mathieu, Le Borgne, Roland, Tournier, Sylvie, Suzanne, Magali, Idier, Jérome, Sentenac, Anne“…We illustrate the potential of RIM on diverse biological applications, from the mobility of proliferating cell nuclear antigen (PCNA) in U2OS cells and kinetochore dynamics in mitotic S. pombe cells to the 3D motion of myosin minifilaments deep inside Drosophila tissues. …”
Publicado 2021
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1150“…These include mutations in the major (U2‐type) and minor (U12‐type) spliceosomes, which remove >99% and ~0.35% of introns, respectively. …”
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1151por Rahman, M Julhasur, Haller, Sherry L, Stoian, Ana MM, Li, Jie, Brennan, Greg, Rothenburg, Stefan“…In one case, the acquired gene integrated together with a polyadenylated host U2 small nuclear RNA. Integrations occurred across the genome, in some cases knocking out essential viral genes. …”
Publicado 2022
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1152“…In addition, phosphorylation increased not only the components of the ERK signaling pathway but also U2AF65 and SPF45, known splicing factors. Therefore, we propose a novel mechanism of α-AMA as follows. …”
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1153por Lin, Weiwen, Li, Hanpeng, Wu, Zhiwen, Su, Jingyi, Zhang, Zehong, Yang, Li, Deng, Xianming, Xu, Qingyan“…No compound showed antimicrobial activity, but at a concentration of 1 μM, compounds 1 and 6 exhibited the highest inhibition rates of 71.2% and 83.4% against JeKo-1 cells and U2OS cells, respectively.…”
Publicado 2022
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1154“…The latter are the arguments of the dispersive and absorptive mixing amplitudes M12 and Γ12, relative to their dominant (ΔU=2) U-spin components. The intrinsic phases are experimentally accessible due to approximate universality: in the SM, and in extensions with negligible new CPV phases in Cabibbo favored/doubly Cabibbo suppressed (CF/DCS) decays, the deviation of ϕfM,Γ from ϕ2M,Γ is negligible in CF/DCS decays D0→K±X, and below 10% in CF/DCS decays D0→KS,LX (up to precisely known O(εK) corrections). …”
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1155por Arikawa, Shino, Tchankoni, Martin Kouame, Gbeasor-Komlanvi, Fifonsi A., Atekpe, Somiabalo P., Atcha-Oubou, Tinah, Figueroa-Romero, Antía, Fombah, Augustin E., Saute, Francisco, Samai, Mohamed, Menendez, Clara, Gonzalez, Raquel, Briand, Valérie, Ekouevi, Didier K.“…CONCLUSION: One-third of the children U2 who participated in this survey had malaria infection, thus PMC could be a promising strategy to reduce malaria burden in young children in Plateaux region. …”
Publicado 2023
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1156“…At leading order in the small symmetry breaking parameter u, which is of the same order as the reactor mixing angle theta_{13}, we find that the branching ratios generically scale as u^2. Applying the current bound on the branching ratio of mu -> e gamma shows that small values of u or tan(beta) are preferred in the model for mass parameters m_{SUSY} and m_{1/2} smaller than 1000 GeV. …”
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1157por Lopienski, Sebastian“…</span></p> Computing Seminar: Web security series: https://cern.zoom.us/j/95038883222?pwd=NFEyU2Q0UGhYdU9kRDdFRHZ2N3ZnZz09…”
Publicado 2021
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1158por Lopienski, Sebastian“…</span></p> Computing Seminar: Web security series: https://cern.zoom.us/j/95038883222?pwd=NFEyU2Q0UGhYdU9kRDdFRHZ2N3ZnZz09…”
Publicado 2021
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1159“…They are presented for A549 human melanoma, E. coli, osteosarcoma, U2-OS, SAOS-2, MG63, U87, and U118 cell lines. Then, important drug release issues are discussed. …”
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1160Pushed to the edge: hundreds of Myosin 10s pack into filopodia and could cause traffic jams on actin“…Here we combined SDS-PAGE analysis with epifluorescence microscopy to quantitate HaloTag-labeled Myo10 in U2OS cells. About 6% of total intracellular Myo10 localizes to filopodia, where it tends to be enriched at opposite ends of the cell. …”
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