“…This is the first study examining the anti-epithelial-mesenchymal transition (EMT) effects of α-viniferin and ε-viniferin on A549, NCI-H460, NCI-H520, MCF-7, HOS, and U2OS cells. The results showed that α-viniferin and ε-viniferin significantly inhibited EMT, invasion and migration in TGF-β1- or IL-1β-induced non-small cell lung cancer. α-Viniferin and ε-viniferin also reversed TGF-β1-induced reactive oxygen species (ROS), MMP2, vimentin, Zeb1, Snail, p-SMAD2, p-SMAD3, and ABCG2 expression in A549 cells. …”
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“…KC(8) reduces the complex, affording [K(2.2.2-cryptand)][{((Me(3)Si)(2)N)(3)U}(2)(μ-bpym)], 2, which is best described as a radical-bridged U(III)–bpym˙(−)–U(III) complex. …”
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“…Main results and conclusions: Two canonical varieties were built (Cor (U(1),V(1)) = 0.442; Cor (U(2),V(2)) = 0.270). Minors with high scores in cyber-victimisation (r = −0.888) and bystanding (r = −0.902) would have more favourable attitude towards violence, greater number of contacts on social networks/messaging and greater attention to emotions. …”
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“…Association analysis of somatic variants with alternative splicing events confirmed known trans associations with variants in SF3B1 and U2AF1 and identified additional trans-acting variants (e.g., TADA1, PPP2R1A). …”
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“…At the string scale, the gauge group is U(3)_color x U(2)_weak x U(1)_1 x U(1)_bulk. The corresponding gauge bosons are localized on three collections of branes; two of them describe the strong and weak interactions, while the last abelian factor lives on a brane which is extended in two large extra dimensions with a size of afew microns. …”
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“…Furthermore, CPn0443-transfected U2OS cells had a significantly reduced infection rate by C. pneumoniae EBs. …”
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“…The XRD analysis revealed that uranium compounds had the reaction paths of UO(3) → UO(2.92) → U(3)O(8) and UO(3) → K(2)U(2)O(7) → K(2)UO(4) in the carbonate melt, and sulfur elements in resins were fixed in the form of K(3)Na(SO(4))(2). …”
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“…In contrast to other RPs, the knockdown of either RPS27a or RPL40 did not stabilise the tumour suppressor p53 in U2OS cells. Knockdown of neither protein blocked p53 stabilisation following inhibition of ribosome biogenesis by actinomycin D, indicating that they are not needed for p53 signalling in these cells. …”
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“…Subsequent re-training further increases segmentation performance (mIoU + 2.81%). For re-training, finetuning with dynamic knowledge distillation showed the most promising results. …”
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“…In the mouse, three imprinted genes have been described that originated by retrotransposition and overlap CpG islands which undergo methylation during oogenesis. Nap1l5, U2af1-rs1, and Inpp5f_v2 are likely to encode proteins and share two additional genetic properties: they are located within introns of host transcripts and are derived from parental genes on the X chromosome. …”
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“…Depletion of PTB from nuclear extracts facilitated U2AF(65) binding to wild type sequence in vitro, suggesting these proteins function in a dynamic equilibrium to modulate fosB pre-mRNA alternative splicing. …”
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“…In addition, when transcription is activated at the twelfth cleavage (4,000 cell-stage), the snRNAs U1, U2, U4, U5, and U6 are major RNA polymerase II products. …”
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“…Anti-snRNP antibodies, directed either against the Sm- antigen (common for nucleoplasmic snRNP species containing U1, U2, U4, U5, and U6 RNAs) or against U1-snRNP, were bound by two morphological types of RNP structures. …”
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“…Using fluorescent 2'O-methyl oligoribonucleotide probes, we investigated the mobility of poly(A)(+) RNA in the nucleoplasm and in nuclear speckles of U2OS cells. Quantitative analysis of diffusion using photobleaching techniques revealed that the majority of poly(A)(+) RNA move throughout the nucleus, including in and out of speckles (also called SC-35 domains), which are enriched for splicing factors. …”
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“…Examples are RNAs of the major (U2-type) spliceosome in all fungal lineages, in lower metazoa and many protozoa. …”
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“…The IL complex contains U2, U5 and U6 snRNAs and other protein splicing factors, whereas the IS complex contains no such U snRNAs or proteins. …”
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“…The C/D box scaRNA2 is predicted to guide specific 2′-O-methylation of U2 snRNA. In contrast to other SCARNA genes, SCARNA2 appears to be independently transcribed. …”
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“…Here, we show a role for the transcriptional regulator p8 in autophagy. p8 RNA interference (RNAi) increases basal autophagy markers in primary cardiomyocytes, in H9C2 and U2OS cells, and decreases cellular viability after autophagy induction. …”
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“…The reaction was optimized and shown to depend on ATP and intact U2 and U6 snRNPs. Mutations introduced at the polypyrimidine tract and the AG splice site reduced the reaction efficiency. …”
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