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Mostrando 381 - 400 Resultados de 770 Para Buscar '"UBA"', tiempo de consulta: 0.17s Limitar resultados
  1. 381
    “…The Hakuba actinobacterium is a member of the clade UBA1414/RBG-16-55-12, formerly within the group “OPB41.” …”
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    Single-Cell Genomics of Novel Actinobacteria With the Wood–Ljungdahl Pathway Discovered in a Serpentinizing System
  2. 382
    “…Moreover, a significant correlation between TUFT1 mRNA and UBA2, GLO1, STATH (negative correlation), and TUFT1 in relation to CA-125 and HE4 (p < 0.05) was noted in all patients. …”
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    Clinical and molecular evaluation of patients with ovarian cancer in the context of drug resistance to chemotherapy
  3. 383
    “…We are able to show that the ERAD system is essential for parasite survival and that the putative Plasmodium HRD1 (E3 ubiquitin ligase), UBC (E2 ubiquitin conjugating enzyme) and UBA1 (E1 ubiquitin activating enzyme) are able to mediate in vitro ubiquitylation. …”
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    Characterization of the Ubiquitylating Components of the Human Malaria Parasite’s Protein Degradation Pathway
  4. 384
    “…Here we provide data suggesting that two of the four mammalian ubiquitin precursors, UBA52 and UBA80, are processed mostly post-translationally whereas the other two, UBB and UBC, probably undergo a combination of co- and post-translational processing. …”
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    The de novo synthesis of ubiquitin: identification of deubiquitinases acting on ubiquitin precursors
  5. 385
    “…OBJECTIVES: The objectives of this study were to determine the prevalence of sleep paralysis (SP) in medical students from the University of Buenos Aires (UBA). MATERIALS AND METHODS: An ad hoc questionnaire based on the diagnosis of SP and a demographic survey was electronically presented to students of Internal Medicine at the School of Medicine of the UBA. …”
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    The prevalence of sleep paralysis in medical students in Buenos Aires, Argentina
  6. 386
    por Katsura, Yukako, Satta, Yoko
    Publicado 2012
    “…In this study, we analyzed the following 7 pairs of marsupial gametologs, together with their eutherian orthologs that reside in stratum 1 or 2: SOX3/SRY, RBMX/Y, RPS4X/Y, HSFX/Y, XKRX/Y, SMCX/Y (KDM5C/D, JARID1C/D), and UBE1X/Y (UBA1/UBA1Y). Phylogenetic analyses and estimated divergence time of these gametologs reveal that they all differentiated at the same time in the therian ancestor. …”
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    No Evidence for a Second Evolutionary Stratum during the Early Evolution of Mammalian Sex Chromosomes
  7. 387
    “…EGCG directly and reversibly targets the ubiquitin-activating enzyme Uba1, blocking formation of the Uba1~ubiquitin thioester conjugate and thus ubiquitination and in the cell. …”
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    Multilevel structure–activity profiling reveals multiple green tea compound families that each modulate ubiquitin-activating enzyme and ubiquitination by a distinct mechanism
  8. 388
    “…The recently described vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome is caused by somatic mutations in UBA1. Patients with VEXAS syndrome display late-onset autoinflammatory symptoms, usually refractory to treatment, and hematologic abnormalities. …”
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    Successful allogeneic hematopoietic stem cell transplantation in patients with VEXAS syndrome: a 2-center experience
  9. 389
    “…Our results revealed that during the soluble receptor activator of nuclear factor-κB ligand (sRANKL)-stimulated osteoclast differentiation, the neddylation and expression of UBA3, the NEDD8-activating enzyme (NAE) catalytic subunit, were dose- and time-dependently upregulated in RAW 264.7 macrophages. …”
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    Inhibition of Neddylation Suppresses Osteoclast Differentiation and Function In Vitro and Alleviates Osteoporosis In Vivo
  10. 390
    Publicado 1997
    Libro
    La novela latinoamericana de entresiglos /
  11. 391
    por Brown, Robert B.
    Publicado 1971
    Tabla de Contenidos: “…--Everything and nothing, by J. L. Borges.--Uba-Opa, by M. Aub.--En una noche así, by M. Delibes.…”
    Libro
    Visiones de hoy /
  12. 392
    “…Seventeen pathogenic variants were detected from IEI-related genes, BTK, UNC13D, STAT3, IL2RG, IL10RA, NRAS, SH2D1A, GATA2, TET2, PRF1, and UBA1, of which four variants were previously unreported. …”
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    Genetic diagnosis of inborn errors of immunity using clinical exome sequencing
  13. 393
    “…The tandem Ub-associated (UBA) domains of USP13 can bind with different types of diUb but preferentially with K63-linked, providing a possible explanation for the weak activity preferring to K63-polyUb. …”
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    Domain Analysis Reveals That a Deubiquitinating Enzyme USP13 Performs Non-Activating Catalysis for Lys63-Linked Polyubiquitin
  14. 394
    “…Genetic study has demonstrated that the Ufm1-activating enzyme Uba5 is indispensible for erythroid differentiation in mice, highlighting the importance of this novel system in animal development. …”
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    Transcriptional Regulation of the Ufm1 Conjugation System in Response to Disturbance of the Endoplasmic Reticulum Homeostasis and Inhibition of Vesicle Trafficking
  15. 395
    “…The ubiquitin-activating E1 enzyme homolog of archaea (UbaA) was required for this covalent modification. …”
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    Archaeal Tuc1/Ncs6 Homolog Required for Wobble Uridine tRNA Thiolation Is Associated with Ubiquitin-Proteasome, Translation, and RNA Processing System Homologs
  16. 396
    “…The mass-spectrometry analysis of TRPM8, immunoprecipitated from LNCaP cells identified ubiquitin-like modifier-activating enzyme 1 (UBA1). PYR-41, a potent inhibitor of initial enzyme in the ubiquitination cascade, UBA1, increased TRPM8 activity on the plasma membrane (PM) of LNCaP cells. …”
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    TRPM8 channel as a novel molecular target in androgen-regulated prostate cancer cells
  17. 397
    “…Subcellular distribution of UBA1 was predominantly cytoplasmic in SMA motor neurons in contrast to nuclear in control motor neurons; suggestive of neurodevelopmental abnormalities. …”
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    Spinal Muscular Atrophy Patient iPSC-Derived Motor Neurons Have Reduced Expression of Proteins Important in Neuronal Development
  18. 398
    “…By virtue of its ubiquitin-like (UBL) and ubiquitin-associated (UBA) domains, it has been proposed to serve as a proteasomal shuttle factor. …”
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    Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog
  19. 399
    “…The sampling took place in Ubatumirim (UBM), Ubatuba (UBA) and Mar Virado (MV) bays, located in the northern coast of São Paulo State (Brazil). …”
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    Modulating factors of the abundance and distribution of Achelous spinimanus (Latreille, 1819) (Decapoda, Portunoidea), a fishery resource, in Southeastern Brazil
  20. 400
    “…Here we show that ubiquitin could recognize Mtb surface protein Rv1468c, a previously unidentified ubiquitin-binding protein containing a eukaryotic-like ubiquitin-associated (UBA) domain. The UBA-mediated direct binding of ubiquitin to, but not E3 ubiquitin ligases-mediated ubiquitination of, Rv1468c recruits autophagy receptor p62 to deliver mycobacteria into LC3-associated autophagosomes. …”
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    A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy
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