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Mostrando 441 - 460 Resultados de 770 Para Buscar '"UBA"', tiempo de consulta: 0.18s Limitar resultados
  1. 441
    “…Blood samples were examined for VEXAS-associated UBA1 variants by Sanger sequencing at the department of Clinical Immunology, AUH. …”
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    Patients with VEXAS diagnosed in a Danish tertiary rheumatology setting have highly elevated inflammatory markers, macrocytic anaemia and negative autoimmune biomarkers
  2. 442
    “…There were many overlapping DEGs between UMS and RS transcriptional data sets, where 1406 DEGs were associated with both biological sex and stress, while only 117 DEGs were related to stress. Notably, Uba52 and Rpl34-ps1 were the first-ranked hub gene in 1406 and 117 DEGs respectively, and Uba52 was higher than Rp134-ps1, suggesting that stress may have led to a more pronounced effect on the set of 1406 DEGs. …”
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    Sex-specific transcriptional signatures in the medial prefrontal cortex underlying sexually dimorphic behavioural responses to stress in rats
  3. 443
    “…This dataset is part of a risk assessment project that evaluated the human health effects of pesticide exposure in São José de Ubá, State of Rio de Janeiro. This region is one of the greatest tomato producers in Brazil, and pest control is commonly based on the use of pesticides. …”
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    Data on pesticide exposure and mental health screening of family farmers in Brazil
  4. 444
    “…Two allelic BACs spanning the UBA locus had 99.2% identity over 125 kb, while the IA region showed 82.5% identity over 136 kb to the IB region. …”
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    Genomic organization of duplicated major histocompatibility complex class I regions in Atlantic salmon (Salmo salar)
  5. 445
    “…RESULTS: To identify which USP5 domain is responsible for the interaction, we used a series of USP5-derived peptides corresponding to different regions in nUBP, cUBP, UBA1, and UBA2 domains to outcompete full length USP5. …”
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    A cell-permeant peptide corresponding to the cUBP domain of USP5 reverses inflammatory and neuropathic pain
  6. 446
    “…Second-generation devices utilized during the study period included the radiofrequency ablation device (RFA), hydrothermal ablation device (HTA), and the uterine balloon ablation system (UBA). RESULTS: Five thousand nine hundred thirty-six women underwent endometrial ablation at a single institution (3757 RFA (63.3%), 1848 HTA (31.1%), and 331 UBA (5.6%)). …”
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    Incidence and predictors of failed second-generation endometrial ablation
  7. 447
    “…(A. aquatilis BU33N, A. faecalis JQ135, A. faecalis UBA3227, and A. faecalis UBA7629). Genomic sequence analyses of A. aquatilis QD168 with 25 Alcaligenes spp., using ANIb, indicated that A. aquatilis BU33N is the closest related strain, with 96.8% ANIb similarity. …”
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    Genomic and Physiological Traits of the Marine Bacterium Alcaligenes aquatilis QD168 Isolated From Quintero Bay, Central Chile, Reveal a Robust Adaptive Response to Environmental Stressors
  8. 448
    “…One unusual feature of TNK1 is a ubiquitin-association domain (UBA) on its C-terminus. Here, we characterize the TNK1 UBA, which has high affinity for poly-ubiquitin. …”
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    TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth
  9. 449
    por Si, Ke, Lu, Da, Tian, Jianbo
    Publicado 2021
    “…Ten hub gene-encoded proteins (namely IL6, RPS27A, JUN, UBC, UBA52, FOS, IL1B, MMP9, SPP1 and CCL2) coupled with a higher degree of connectivity hub were identified after protein‐protein interaction network analysis. …”
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    Integrated analysis and the identification of a circRNA-miRNA-mRNA network in the progression of abdominal aortic aneurysm
  10. 450
    “…Simultaneously, g_Streptococcus, g_Bacteroides, and g_UBA1819 inversely correlated with bile acid, accounting for the great bulk of the difference. …”
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    The Periparturient Gut Microbiota’s Modifications in Shaziling Sows concerning Bile Acids
  11. 451
    “…Here, we report the isolation and genome sequence of strain FT118(T), the first cultured representative of a previously uncultivated order UBA8317 within Alphaproteobacteria, based on the combined results of 16S rRNA gene similarity, phylogenomic, and average amino acid identity analyses. …”
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    Isolation and Genomics of Futiania mangrovii gen. nov., sp. nov., a Rare and Metabolically Versatile Member in the Class Alphaproteobacteria
  12. 452
    por Kucharz, Eugenisz J.
    Publicado 2023
    “…VEXAS syndrome is caused by a somatic mutation of the UBA1 gene in hematopoietic progenitor cells. The clinical picture of the syndrome consists of a number of organ manifestations including those akin to rheumatic diseases, arthritis, myalgia, vasculitis and chondritis.…”
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    VEXAS syndrome: a newly discovered systemic rheumatic disorder
  13. 453
    “…Here we present a unique case of a patient with VEXAS syndrome with coinciding ubiquitin-like modifier activating enzyme 1 (UBA1) and DNA (cytosine-5)-methyltransferase 3A (DNMT3A) mutations who developed cutaneous and systemic reactions to tocilizumab and azacitidine therapy, respectively.…”
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    A Case of VEXAS: Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic Syndrome With Co-existing DNA (Cytosine-5)-Methyltransferase 3A Mutation Complicated by Localized Skin Reaction to Tocilizumab and Azacitidine
  14. 454
    por Chen, Yuzhi, Neve, Rachael L, Liu, Helena
    Publicado 2012
    “…Central to the neddylation pathway is the amyloid precursor protein (APP)-binding protein APP-BP1, which together with Uba3, plays an analogous role to the ubiquitin-activating enzyme E1 in nedd8 activation. …”
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    Neddylation dysfunction in Alzheimer's disease
  15. 455
    “…After a review of the related literature, we suggest testing patients with EEC for 19q13.11 microdeletion and include WTIP and UBA2 to a minimal overlapping region.…”
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    19q13.11 microdeletion: Clinical features overlapping ectrodactyly ectodermal dysplasia‐clefting syndrome phenotype
  16. 456
    “…Moreover, in silico analysis of the common targets of up-regulated miRNAs revealed UBA52 and hsa-miR-7977 as majorly regulated hubs in the PPI and mRNA–miRNA networks, suggesting their putative role in complicated P. vivax malaria. …”
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    Screening and identification of potential novel biomarker for diagnosis of complicated Plasmodium vivax malaria
  17. 457
    “…Based on the literature and our results, it is speculated that the identified DEPs, such as ATP1, SDH2, COR1, UBA1, COX4, UBC1 and SKP1 play a key role in the low-temperature autolysis of V. volvacea.…”
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    Differential proteomics study of postharvest Volvariella volvacea during storage at 4 °C
  18. 458
    “…Sequencing analysis identified the somatic UBA1 variant c.122T > C, which results in p.Met41Thr. …”
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    A case of VEXAS syndrome (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) with decreased oxidative stress levels after oral prednisone and tocilizumab treatment
  19. 459
    por Khoo, Thomas, Chin, Athena, Walker, Jenny
    Publicado 2023
    “…In this case, testing for a UBA1 variant was prompted by widespread inflammatory phenomena and persistent anaemia. …”
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    OA13 The skin as a snapshot of systemic inflammation
  20. 460
    “…Ubiquilins or UBQLNs, members of the ubiquitin-like and ubiquitin-associated domain (UBL-UBA) protein family, serve as adaptors to coordinate the degradation of specific substrates via both proteasome and autophagy pathways. …”
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    Ubiquilin Networking in Cancers
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