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261“…PSD rat models were established with comprehensive separate breeding and unpredicted chronic mild stress (UCMS) on this basis. A normal control group, depression group, and a stroke group were used to compare with the PSD group. …”
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262por Nikolova, Yuliya S., Misquitta, Keith A., Rocco, Brad R., Prevot, Thomas D., Knodt, Annchen R., Ellegood, Jacob, Voineskos, Aristotle N., Lerch, Jason P., Hariri, Ahmad R., Sibille, Etienne, Banasr, Mounira“…Using the unpredictable chronic mild stress (UCMS) paradigm in mouse we first demonstrate that UCMS-induced elevated behavioral emotionality correlates with increased size of the amygdala and other corticolimbic regions. …”
Publicado 2018
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263por Patrício, Patrícia, Mateus-Pinheiro, António, Machado-Santos, Ana Rita, Alves, Nuno Dinis, Correia, Joana Sofia, Morais, Mónica, Bessa, João Miguel, Rodrigues, Ana João, Sousa, Nuno, Pinto, Luísa“…We show that the hippocampal dentate gyrus (hDG) of uCMS animals have less proliferating cells and a decreased proportion of cells in the G2/M phase, suggesting a G1 phase arrest; this is accompanied by decreased levels of cyclin D1, E, and A expression. …”
Publicado 2021
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264por Bansal, Yashika, Fee, Corey, Misquitta, Keith A., Codeluppi, Sierra A., Sibille, Etienne, Berman, Robert M., Coric, Vladimir, Sanacora, Gerard, Banasr, Mounira“…In a separate learned helplessness (LH) cohort, we investigated whether chronic prophylactic riluzole treatment could block the development of helplessness-like behavior. RESULTS: UCMS induced an elevation in anhedonia-like behavior and overall behavioral emotionality that was blocked by prophylactic riluzole. …”
Publicado 2023
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265por Chiang, Chien-Yi, Lin, Yu-Jung, Weng, Wen-Tsan, Lin, Heng-Dao, Lu, Cheng-You, Chen, Wan-Jing, Shih, Cheng Yen, Lin, Pi-Yu, Lin, Shinn-Zong, Ho, Tsung-Jung, Shibu, Marthandam Asokan, Huang, Chih-Yang“…The therapeutic benefits of JSHT on anhedonia and depression symptoms associated with long COVID were evaluated in mice models for unpredictable chronic mild stress (UCMS). JSHT inhibited the NF-ƙB activities, and significantly reduced LPS-induced expression of TNFα, COX-2, NLRP3 inflammasome, and HMGB1. …”
Publicado 2023
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266por Désiré, Guedang Nyayi Simon, Simplice, Foyet Harquin, Guillaume, Camdi Woumitna, Kamal, Fatima Zahra, Parfait, Bouvourné, Hermann, Tchinda Defo Serge, Hervé, Ngatanko Abaissou Hervé, Eglantine, Keugong Wado, Linda, Damo Kamda Jorelle, Roland, Rebe Nhouma, Balbine, Kamleu Nkwingwa, Blondelle, Kenko Djoumessi Lea, Ciobica, Alin, Romila, Laura“…Treatment with AO significantly alleviated UCMS-induced and depressive-like behaviors in rats. …”
Publicado 2023
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267por García-Gutiérrez, María Salud, Navarro, Daniela, Austrich-Olivares, Amaya, Manzanares, Jorge“…CBD modulates all molecular disturbances induced by UCMS, whereas STR and the combination could not restore 5-HT1A, BDNF and PPARdelta in the Hipp. …”
Publicado 2023
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268“…Ethical approval was taken from Institutional Review Committee of Universal College of Medical Sciences and Teaching Hospital (IRC UCMS, Ref: UCMS/IRC/025/20). Convenient sampling method was used. …”
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269por Piantadosi, Sean C., French, Beverly J., Poe, Michael M., Timić, Tamara, Marković, Bojan D., Pabba, Mohan, Seney, Marianne L., Oh, Hyunjung, Orser, Beverley A., Savić, Miroslav M., Cook, James M., Sibille, Etienne“…Methods: Female and male C57BL6/J mice were exposed to unpredictable chronic mild stress (UCMS) and treated with α5-PAM acutely (30 min prior to assessing behavior) or chronically before being assessed behaviorally. …”
Publicado 2016
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270por Zhao, Ya-Fei, Ren, Wen-Jing, Zhang, Ying, He, Jin-Rong, Yin, Hai-Yan, Liao, Yang, Rubini, Patrizia, Deussing, Jan M., Verkhratsky, Alexei, Yuan, Zeng-Qiang, Illes, Peter, Tang, Yong“…We confirmed the participation of P2X7Rs in the development of the depressive-like behaviors in all forms of acute (TST, FST, foot shock) and chronic stress (UCMS) in the rodent models used. Further, pharmacological agonists and antagonists acted in a different manner in rats and mice due to their diverse potencies at the respective receptor orthologs. …”
Publicado 2022
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271por Maneenet, Juthamart, Daodee, Supawadee, Monthakantirat, Orawan, Boonyarat, Chantana, Khamphukdee, Charinya, Kwankhao, Pakakrong, Pitiporn, Supaporn, Awale, Suresh, Chulikhit, Yaowared, Kijjoa, Anake“…Oral administration of KBD to unpredictable chronic mild stress (UCMS) mice significantly improved their cognitive function caused by chronic mild stress. …”
Publicado 2019
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273por Montanucci, Pia, di Pasquali, Camilla, Ferri, Ivana, Pescara, Teresa, Pennoni, Ilaria, Siccu, Paola, Sidoni, Angelo, Cervelli, Valerio, Basta, Giuseppe, Calafiore, Riccardo“…To this end, we have assembled a new prototype of a biomimetic human umbilical cord adult mesenchymal stem cell (hUCMS)/fibrin-based scaffold. We have fully characterized the proposed dermal equivalent (DE) in vitro, to assess morphological, functional, and biological properties of the encased cells. …”
Publicado 2017
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274por Naik, Roshan R., Sotnikov, Sergey V., Diepold, Rebekka P., Iurato, Stella, Markt, Patrick O., Bultmann, Andrea, Brehm, Nadine, Mattheus, Tobias, Lutz, Beat, Erhardt, Angelika, Binder, Elisabeth B., Schmidt, Ulrike, Holsboer, Florian, Landgraf, Rainer, Czibere, Ludwig“…While LAB mice subjected to unpredictable chronic mild stress (LAB-UCMS) exhibited higher anxiety levels and had lower mRNA expression compared to standard-housed LAB (LAB-SH) mice. …”
Publicado 2018
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275por Agrawaal, Krishna Kumar“…Ethical approval was taken from the Institutional Review Committee (Reference number: UCMS/IRC/132/22). All patients receiving maintenance hemodialysis were enrolled in the study. …”
Publicado 2022
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276por Shlomi, Shir, Toledano, Roni, Nitzan, Keren, Shahaf, Sigal Dror, Break, Emanuela P., Frenkel, Dan, Doron, Ravid“…One-month-old mice were exposed to 4 weeks of UCMS and examined for anxiety and cognition at the age of 2, 4 and 6 months. …”
Publicado 2022
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277por Machado-Santos, Ana R., Loureiro-Campos, Eduardo, Patrício, Patrícia, Araújo, Bruna, Alves, Nuno Dinis, Mateus-Pinheiro, António, Correia, Joana Sofia, Morais, Mónica, Bessa, João M., Sousa, Nuno, Rodrigues, Ana J., Oliveira, João Filipe, Pinto, Luísa“…Therefore, we studied the modulation of astrocytes and adult astrogliogenesis in the hippocampal dentate gyrus (DG) of rats exposed to an unpredictable chronic mild stress (uCMS) protocol, untreated and treated for two weeks with antidepressants—fluoxetine and imipramine. …”
Publicado 2022
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278“…METHODS: This retrospective study comprised a total of 23 patients with upper respiratory infection investigated in the Department of Microbiology of University College of Medical Sciences (UCMS) and Guru Teg Bahadur Hospital (GTBH), Delhi from April 2021 to June 2021. …”
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279por Li, Yingxiao, Cheng, Kai-Chun, Liu, Keng-Fan, Peng, Wen-Huang, Cheng, Juei-Tang, Niu, Ho-Shan“…In unpredictable chronic mild stress (UCMS) model, treatment with telmisartan for five weeks notably decrease in the time spent in the central and the reduced frequency of grooming and rearing in open filed test (OFT) and the decreased sucrose consumption in sucrose preference test (SPT) compared with the paradigms. …”
Publicado 2017
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280por Halwai, Hemant Kumar, Kamble, Ranjit Haridas, Yadav, Sumit Kumar, Gupta, Sandeep Kumar, Shrestha, Raju, Daigavane, Pallavi, Gilani, Rizwan“…METHODS: A descriptive cross-sectional study was performed at the Department of Orthodontics and Dentofacial Orthopedics at a tertiary care centre from 15 January 2022 to 28 June 2022 after taking ethical approval from the Institutional Review Committee (Reference number: UCMS/IRC/175/21). Data was collected from scan reports obtained with a computed tomography scanner. …”
Publicado 2023
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