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  1. 367701
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    Cross-suppression of EGFR ligands amphiregulin and epiregulin and de-repression of FGFR3 signalling contribute to cetuximab resistance in wild-type KRAS tumour cells
  2. 367702
    “…The data strengthen previous evidence to treat patients as early as possible after acute ischaemic stroke, although some patients might benefit up to 6 h after stroke. FUNDING: UK Medical Research Council, Stroke Association, University of Edinburgh, National Health Service Health Technology Assessment Programme, Swedish Heart-Lung Fund, AFA Insurances Stockholm (Arbetsmarknadens Partners Forsakringsbolag), Karolinska Institute, Marianne and Marcus Wallenberg Foundation, Research Council of Norway, Oslo University Hospital.…”
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    Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis
  3. 367703
    “…E-mail: sarah.lock@hpa.org.uk…”
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    Secondary stressors and extreme events and disasters: a systematic review of primary research from 2010-2011
  4. 367704
    por Grady, Katherine, Savas, Linda
    Publicado 2012
    “…INTRODUCTION: Diabetes is one of the major health challenges of our time. Diabetes UK recently estimated 10% of the total NHS budget is spent on diabetes care. …”
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    An innovative approach to providing lifestyle education and behaviour change to prevent type 2 diabetes
  5. 367705
    “…FUNDING: Cancer Research UK, MRC Clinical Trials Unit.…”
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    Cardiovascular outcomes in patients with locally advanced and metastatic prostate cancer treated with luteinising-hormone-releasing-hormone agonists or transdermal oestrogen: the randomised, phase 2 MRC PATCH trial (PR09)
  6. 367706
    “…INTERPRETATION: Existing ICDS village staff can be organised to deliver simple pre-school interventions sustainably for many years at low cost, but regular deworming had little effect on mortality in this lightly infected pre-school population. FUNDING: UK Medical Research Council, USAID, World Bank (albendazole donated by GlaxoSmithKline).…”
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    Population deworming every 6 months with albendazole in 1 million pre-school children in north India: DEVTA, a cluster-randomised trial
  7. 367707
    “…Some studies of similar systems were performed in the UK (1), Hong Kong (2), and the USA (3,4), examined surveillance systems for monitoring infectious disease incidence, but the systems to construct in those studies do not operate nationwide like SASSy or NSASSy, and they cannot provide influenza incidence rates in children. …”
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    Estimation of Influenza Incidence by Age in the 2011/12 Seasons in Japan using SASSy
  8. 367708
    “…Among official sources, national government affiliated institutes were most often (41%) the fastest, and repeatedly providing prompt outbreak reports were the US Centers for Disease Control and Prevention (CDC), Public Health Agency of Canada, Finnish Food Safety Authority, Health Protection Scotland, UK Health Protection Agency, and French Institute of Public Health Surveillance (FIPHS). …”
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    MoH+: A Global, Integrated, and Automated View of Official Outbreak Reporting
  9. 367709
    “…METHODS: We conducted a multi-centre case notes review of 44 SURF1-deficient patients from ten different UK centres and two Australian centres. Survival data for LRPPRC-deficient LS and nuclear-encoded complex I-deficient LS patients were obtained from previous publications. …”
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    SURF1 deficiency: a multi-centre natural history study
  10. 367710
    por Min, D, Lv, X-b, Wang, X, Zhang, B, Meng, W, Yu, F, Hu, H
    Publicado 2013
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    Downregulation of miR-302c and miR-520c by 1,25(OH)2D3 treatment enhances the susceptibility of tumour cells to natural killer cell-mediated cytotoxicity
  11. 367711
    “…RecordID=2650 (Archived by WebCite at http://www.webcitation.org/6LzDPhGb8), CRD42012002651; http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42012002651#.UrMglPRDuVo (Archived by WebCite at http://www.webcitation.org/6LzClCNff).…”
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    Diagnosis and Prediction of Neuroendocrine Liver Metastases: A Protocol of Six Systematic Reviews
  12. 367712
    por Kim, H S, Kim, T H, Chung, H H, Song, Y S
    Publicado 2014
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    Risk and prognosis of ovarian cancer in women with endometriosis: a meta-analysis
  13. 367713
    “…The Cochrane Collaboration was established in 1993, following the opening of the UK Cochrane Centre in 1992, at a time when searching for studies for inclusion in systematic reviews was not well-developed. …”
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    Methodological developments in searching for studies for systematic reviews: past, present and future?
  14. 367714
    “…Large reductions in consumption in this group would however coincide with substantial health gains in terms of morbidity and mortality related to reduced alcohol consumption. FUNDING: UK Medical Research Council and Economic and Social Research Council (grant G1000043).…”
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    Effects of minimum unit pricing for alcohol on different income and socioeconomic groups: a modelling study
  15. 367715
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    Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells
  16. 367716
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    Clinicopathologic and prognostic significance of c-MYC copy number gain in lung adenocarcinomas
  17. 367717
    “…CONCLUSIONS/INTERPRETATION: For patients with recently diagnosed type 2 diabetes receiving intensive treatment in UK primary care, a facilitator-led individually tailored behaviour change intervention did not improve objectively measured health behaviours or cardiovascular risk factors over 1 year. …”
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    Multiple behaviour change intervention and outcomes in recently diagnosed type 2 diabetes: the ADDITION-Plus randomised controlled trial
  18. 367718
    “…The datasets included 9039 cases and 27 343 controls of European (Australia, Belgium, Italy, UK, USA) and 2467 cases and 5335 controls of Japanese ancestry. …”
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    Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets
  19. 367719
    por Yang, T. O., Reeves, G. K., Green, J., Beral, V., Cairns, B. J., Abbiss, Hayley, Abbott, Simon, Armstrong, Miranda, Balkwill, Angela, Benson, Vicky, Beral, Valerie, Black, Judith, Bradbury, Kathryn, Brown, Anna, Buron, Andrea, Cairns, Benjamin, Canoy, Dexter, Chadwick, Andrew, Crossley, Barbara, Crowe, Francesca, Ewart, Dave, Ewart, Sarah, Fletcher, Lee, Floud, Sarah, Gathani, Toral, Gerrard, Laura, Goodill, Adrian, Green, Jane, Guiver, Lynden, Hozak, Michal, Kan, Sau Wan, Key, Tim, Kirichek, Oksana, Kroll, Mary, Langston, Nicky, Lingard, Isobel, Luque, Maria Jose, Moser, Kath, Pank, Lynn, Pirie, Kirstin, Reeves, Gillian, Shaw, Keith, Sherman, Emma, Sherry-Starmer, Evie, Schmidt, Julie, Strange, Helena, Sweetland, Sian, Timadjer, Alison, Tipper, Sarah, Travis, Ruth, Trickett, Lyndsey, Wright, Lucy, Yang, Owen, Young, Heather
    Publicado 2014
    “…Here, we report on associations between birth weight and cause-specific cancer risk in a large cohort of UK women, and investigate how observed associations are affected by other factors. …”
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    Birth weight and adult cancer incidence: large prospective study and meta-analysis
  20. 367720
    “…Further follow-up of this cohort of patients is likely to allow refinement of the criteria for this experimental procedure in girls and young women with cancer. FUNDING: UK Medical Research Council.…”
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    Fertility preservation for girls and young women with cancer: population-based validation of criteria for ovarian tissue cryopreservation
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