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369581por van Velzen, Laura S., Kelly, Sinead, Isaev, Dmitry, Aleman, Andre, Aftanas, Lyubomir I., Bauer, Jochen, Baune, Bernhard T., Brak, Ivan V., Carballedo, Angela, Connolly, Colm G., Couvy-Duchesne, Baptiste, Cullen, Kathryn R., Danilenko, Konstantin V., Dannlowski, Udo, Enneking, Verena, Filimonova, Elena, Förster, Katharina, Frodl, Thomas, Gotlib, Ian H., Groenewold, Nynke A., Grotegerd, Dominik, Harris, Mathew A., Hatton, Sean N., Hawkins, Emma L., Hickie, Ian B., Ho, Tiffany C., Jansen, Andreas, Kircher, Tilo, Klimes-Dougan, Bonnie, Kochunov, Peter, Krug, Axel, Lagopoulos, Jim, Lee, Renick, Lett, Tristram A., Li, Meng, MacMaster, Frank P., Martin, Nicholas G., McIntosh, Andrew M., McLellan, Quinn, Meinert, Susanne, Nenadić, Igor, Osipov, Evgeny, Penninx, Brenda W. J. H., Portella, Maria J., Repple, Jonathan, Roos, Annerine, Sacchet, Matthew D., Sämann, Philipp G., Schnell, Knut, Shen, Xueyi, Sim, Kang, Stein, Dan J., van Tol, Marie-Jose, Tomyshev, Alexander S., Tozzi, Leonardo, Veer, Ilya M., Vermeiren, Robert, Vives-Gilabert, Yolanda, Walter, Henrik, Walter, Martin, van der Wee, Nic J. A., van der Werff, Steven J. A., Schreiner, Melinda Westlund, Whalley, Heather C., Wright, Margaret J., Yang, Tony T., Zhu, Alyssa, Veltman, Dick J., Thompson, Paul M., Jahanshad, Neda, Schmaal, LianneEnlace del recurso
Publicado 2019
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369582por Lee, Rebecca Rachael, Shoop-Worrall, Stephanie, Rashid, Amir, Thomson, Wendy, Cordingley, Lis“…METHODS: An N-of-1 trial was conducted in a subset of children and young people with JIA and their parents recruited to a UK cohort study. Children were allocated to 1 of 4 groups. …”
Publicado 2020
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369583por Gifford, Fiona J., Dunne, Philip D. J., Weir, Graeme, Ireland, Hamish, Graham, Catriona, Tuck, Sharon, Hayes, Peter C., Fallowfield, Jonathan A.“…METHODS: In a phase 2, double-blind, randomised controlled study conducted in a single centre (Royal Infirmary of Edinburgh, UK), male and female adult participants with cirrhosis and clinically significant PH (CSPH; hepatic venous pressure gradient (HVPG) > 10 mmHg) were enrolled. …”
Publicado 2020
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369584por Thomas, H. J. D., Bjorkman, A. D., Myers-Smith, I. H., Elmendorf, S. C., Kattge, J., Diaz, S., Vellend, M., Blok, D., Cornelissen, J. H. C., Forbes, B. C., Henry, G. H. R., Hollister, R. D., Normand, S., Prevéy, J. S., Rixen, C., Schaepman-Strub, G., Wilmking, M., Wipf, S., Cornwell, W. K., Beck, P. S. A., Georges, D., Goetz, S. J., Guay, K. C., Rüger, N., Soudzilovskaia, N. A., Spasojevic, M. J., Alatalo, J. M., Alexander, H. D., Anadon-Rosell, A., Angers-Blondin, S., te Beest, M., Berner, L. T., Björk, R. G., Buchwal, A., Buras, A., Carbognani, M., Christie, K. S., Collier, L. S., Cooper, E. J., Elberling, B., Eskelinen, A., Frei, E. R., Grau, O., Grogan, P., Hallinger, M., Heijmans, M. M. P. D., Hermanutz, L., Hudson, J. M. G., Johnstone, J. F., Hülber, K., Iturrate-Garcia, M., Iversen, C. M., Jaroszynska, F., Kaarlejarvi, E., Kulonen, A., Lamarque, L. J., Lantz, T. C., Lévesque, E., Little, C. J., Michelsen, A., Milbau, A., Nabe-Nielsen, J., Nielsen, S. S., Ninot, J. M., Oberbauer, S. F., Olofsson, J., Onipchenko, V. G., Petraglia, A., Rumpf, S. B., Shetti, R., Speed, J. D. M., Suding, K. N., Tape, K. D., Tomaselli, M., Trant, A. J., Treier, U. A., Tremblay, M., Venn, S. E., Vowles, T., Weijers, S., Wookey, P. A., Zamin, T. J., Bahn, M., Blonder, B., van Bodegom, P. M., Bond-Lamberty, B., Campetella, G., Cerabolini, B. E. L., Chapin, F. S., Craine, J. M., Dainese, M., Green, W. A., Jansen, S., Kleyer, M., Manning, P., Niinemets, Ü., Onoda, Y., Ozinga, W. A., Peñuelas, J., Poschlod, P., Reich, P. B., Sandel, B., Schamp, B. S., Sheremetiev, S. N., de Vries, F. T.Enlace del recurso
Publicado 2020
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369585por Wang, Ping, Liu, Qiong, Zhao, Hongwei, Bishop, Jack Owen, Zhou, Guoli, Olson, L. Karl, Moore, AnnaEnlace del recurso
Publicado 2020
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369586por Hellewell, Joel, Abbott, Sam, Gimma, Amy, Bosse, Nikos I, Jarvis, Christopher I, Russell, Timothy W, Munday, James D, Kucharski, Adam J, Edmunds, W John, Funk, Sebastian, Eggo, Rosalind M“…FUNDING: Wellcome Trust, Global Challenges Research Fund, and Health Data Research UK.…”
Publicado 2020
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369587por Maher, Toby M., Simpson, Juliet K., Porter, Joanna C., Wilson, Frederick J., Chan, Robert, Eames, Rhena, Cui, Yi, Siederer, Sarah, Parry, Simon, Kenny, Julia, Slack, Robert J., Sahota, Jagdeep, Paul, Lyn, Saunders, Peter, Molyneaux, Philip L., Lukey, Pauline T., Rizzo, Gaia, Searle, Graham E., Marshall, Richard P., Saleem, Azeem, Kang’ombe, Arthur R., Fairman, David, Fahy, William A., Vahdati-Bolouri, Mitra“…METHODS: This was a phase 1b, randomised, double-blind (sponsor unblind) study, conducted in the UK (two clinical sites, one imaging unit) between June 2017 and July 2018 (NCT03069989). …”
Publicado 2020
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369588por Sun, Xudong, Li, Hui, Thapa, Santosh, Reddy Sangireddy, Sasikiran, Pei, Xiaobo, Liu, Wei, Jiang, Yuping, Yang, Shaolan, Hui, Dafeng, Bhatti, Sarabjit, Zhou, Suping, Yang, Yong, Fish, Tara, Thannhauser, Theodore W.Enlace del recurso
Publicado 2020
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369589por Hurford, Robert, Wolters, Frank J, Li, Linxin, Lau, Kui Kai, Küker, Wilhelm, Rothwell, Peter M“…METHODS: The Oxford Vascular Study (OXVASC) is a prospective incidence cohort study of all vascular events in a population of 92 728 people residing in Oxfordshire, UK. All patients, irrespective of age, with transient ischaemic attack and minor ischaemic stroke occurring between March 1, 2011, and March 1, 2018 (follow-up to Sept 28, 2018), were ascertained with multiple methods, including assessment in a dedicated daily emergency clinic and daily review of all hospital admissions. …”
Publicado 2020
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369590por Kearsley-Fleet, Lianne, Heaf, Eleanor, Davies, Rebecca, Baildam, Eileen, Beresford, Michael W, Foster, Helen E, Southwood, Taunton R, Thomson, Wendy, Hyrich, Kimme L“…METHODS: Our study population comprised patients with juvenile idiopathic arthritis who were enrolled in two parallel UK cohort studies (the British Society for Paediatric and Adolescent Rheumatology Etanercept Cohort Study [BSPAR-ETN] and the Biologics for Children with Rheumatic Diseases [BCRD] study) between Jan 1, 2004, and April 11, 2019. …”
Publicado 2020
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369591por El-Azab, Adel S., Abdel-Aziz, Alaa A.-M., Bua, Silvia, Nocentini, Alessio, AlSaif, Nawaf A., Alanazi, Mohammed M., El-Gendy, Manal A., Ahmed, Hany E. A., Supuran, Claudiu T.Enlace del recurso
Publicado 2020
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369592por Akingbuwa, Wonuola A., Hammerschlag, Anke R., Jami, Eshim S., Allegrini, Andrea G., Karhunen, Ville, Sallis, Hannah, Ask, Helga, Askeland, Ragna B., Baselmans, Bart, Diemer, Elizabeth, Hagenbeek, Fiona A., Havdahl, Alexandra, Hottenga, Jouke-Jan, Mbarek, Hamdi, Rivadeneira, Fernando, Tesli, Martin, van Beijsterveldt, Catharina, Breen, Gerome, Lewis, Cathryn M., Thapar, Anita, Boomsma, Dorret I., Kuja-Halkola, Ralf, Reichborn-Kjennerud, Ted, Magnus, Per, Rimfeld, Kaili, Ystrom, EIVIND, Jarvelin, Marjo-Riitta, Lichtenstein, Paul, Lundstrom, Sebastian, Munafò, Marcus R., Plomin, Robert, Tiemeier, Henning, Nivard, Michel G., Bartels, Meike, Middeldorp, Christel M.“…DESIGN, SETTING, AND PARTICIPANTS: This meta-analysis examined data from 7 ongoing longitudinal birth and childhood cohorts from the UK, the Netherlands, Sweden, Norway, and Finland. …”
Publicado 2020
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369593por Pachetti, Maria, Marini, Bruna, Benedetti, Francesca, Giudici, Fabiola, Mauro, Elisabetta, Storici, Paola, Masciovecchio, Claudio, Angeletti, Silvia, Ciccozzi, Massimo, Gallo, Robert C., Zella, Davide, Ippodrino, Rudy“…We noticed for the first time a silent mutation in RdRp gene in England (UK) on February 9th, 2020 while a different mutation in RdRp changing its amino acid composition emerged on February 20th, 2020 in Italy (Lombardy). …”
Publicado 2020
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369594por Zheng, Xi, Xu, Kailun, Zhou, Biting, Chen, Ting, Huang, Yanqin, Li, Qilong, Wen, Fei, Ge, Weiting, Wang, Jian, Yu, Shaojun, Sun, Lifeng, Zhu, Liang, Liu, Wei, Gao, Huanhuan, Yue, Liang, Cai, Xue, Zhang, Qiushi, Ruan, Guan, Zhu, Tiansheng, Wu, Zhicheng, Zhu, Yi, Shao, Yingkuan, Guo, Tiannan, Zheng, ShuEnlace del recurso
Publicado 2020
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369595por Spaducci, Gilda, Richardson, Sol, McNeill, Ann, Pritchard, Megan, Sanyal, Jyoti, Healey, Andy, Yates, Mary, Robson, Debbie“…We assessed whether system-level changes in a UK mental health organisation improved the recording of the provision of ASK, ADVISE, ACT (OFFER) and consent to referral to specialist smoking cessation support (ACT (CONSENT)). …”
Publicado 2020
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369596por Liu, Lu, Zhao, Min, Xie, Zong-Gang, Liu, Ju, Peng, Hui-Ping, Pei, Yu-Fang, Sun, Hong-Peng, Zhang, Lei“…The first one is the single GWAS of estimated heel BMD (eBMD) in the UK biobank (UKB) cohort (N = 426,824), and the second one is the GWAS meta-analysis of total body BMD (TB-BMD) in 66,628 participants from 30 studies. …”
Publicado 2020
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369597por Lombard, Louise, Farrar, Mallory, Ye, Wenyu, Kim, Yongin, Cotton, Sarah, Buchanan, Andrew S., Jackson, James, Joshi, Shivang“…METHODS: Data were from the 2017 Adelphi Migraine Disease Specific Programme, a cross-sectional survey of primary care physicians, neurologists, and headache specialists and their consulting patients with migraine in the USA, France, Germany, Italy, Spain, and UK. Triptan insufficient responders (TIRs) achieved freedom from headache pain within 2 h of acute treatment in ≤3/5 migraine attacks; triptan responders (TRs) achieved pain freedom within 2 h in ≥4/5 attacks. …”
Publicado 2020
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369598por Pescarini, Julia M, Williamson, Elizabeth, Nery, Joilda S, Ramond, Anna, Ichihara, Maria Yury, Fiaccone, Rosemeire L, Penna, Maria Lucia F, Smeeth, Liam, Rodrigues, Laura C, Penna, Gerson O, Brickley, Elizabeth B, Barreto, Mauricio L“…FUNDING: CONFAP/ESRC/MRC/BBSRC/CNPq/FAPDF–Doenças Negligenciadas, the UK Medical Research Council, the Wellcome Trust, and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior–Brazil (CAPES).…”
Publicado 2020
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369599por Hillyar, Christopher, Rizki, Hirah, Abbassi, Omar, Miles-Dua, Sascha, Clayton, Gillian, Gandamihardja, Tasha, Smith, Simon“…Introduction Breast cancer remains the most common cancer diagnosis in the UK. The current clinical practice utilises two different types of modalities to estimate the prognosis, risk of recurrence and benefit from adjuvant chemotherapy treatment in patients with early breast cancer. …”
Publicado 2020
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369600por Merke, Deborah P, Mallappa, Ashwini, Arlt, Wiebke, de la Perriere, Aude Brac, Hirschberg, Angelica Linden, Juul, Anders, Newell-Price, John D C, Perry, Colin Graham, Prete, Alessandro, Rees, Aled, Reisch, Nicole, Stikkelbroeck, Monica, Touraine, Philippe A, Maltby, Kerry, Treasure, Peter, Porter, John, Ross, Richard John M“…Methods: 6 month, open label, study in 122 patients randomised either to treatment with MRHC (Chronocort®, Diurnal Ltd, Cardiff, UK) twice daily at ~ 0700h & ~2300h, or to remain on their standard GC regimen (hydrocortisone, prednisolone, prednisone, dexamethasone). …”
Publicado 2020
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