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  1. 370401
    “…FUNDING: Novartis Vaccines and Diagnostics division (now part of the GlaxoSmithKline group of companies), Wellcome Trust UK, Medical Research Council: Respiratory and Meningeal Pathogens Research Unit.…”
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    Group B streptococcus vaccination in pregnant women with or without HIV in Africa: a non-randomised phase 2, open-label, multicentre trial
  2. 370402
    por Li, Linxin, Rothwell, Peter M
    Publicado 2016
    “…Conclusion Retrospective studies of UK administrative hospital coding data to determine “weekend effects” on outcome in acute medical conditions, such as stroke, can be undermined by inaccurate coding, which can introduce biases that cannot be reliably dealt with by adjustment for case mix.…”
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    Biases in detection of apparent “weekend effect” on outcome with administrative coding data: population based study of stroke
  3. 370403
    “…METHODS: This multicentre, open-label, parallel group, randomised controlled trial included patients from 17 acute UK NHS trusts. We screened patients aged 18 years or older presenting with grade II–III haemorrhoids. …”
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    Haemorrhoidal artery ligation versus rubber band ligation for the management of symptomatic second-degree and third-degree haemorrhoids (HubBLe): a multicentre, open-label, randomised controlled trial
  4. 370404
    “…FUNDING: Cancer Research UK, Department of Health, and the National Institute for Health Research Cancer Research Network.…”
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    Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5-year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial
  5. 370405
    “…FUNDING: Wellcome Trust, UK, and Global Antibiotic Resistance Partnership, USA.…”
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    Point-of-care C-reactive protein testing to reduce inappropriate use of antibiotics for non-severe acute respiratory infections in Vietnamese primary health care: a randomised controlled trial
  6. 370406
    “…METHODS: In this randomised, controlled, non-inferiority trial, we recruited adults aged 18 years or older meeting Diagnostic and Statistical Manual of Mental Disorders IV criteria for major depressive disorder from primary care and psychological therapy services in Devon, Durham, and Leeds (UK). We excluded people who were receiving psychological therapy, were alcohol or drug dependent, were acutely suicidal or had attempted suicide in the previous 2 months, or were cognitively impaired, or who had bipolar disorder or psychosis or psychotic symptoms. …”
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    Cost and Outcome of Behavioural Activation versus Cognitive Behavioural Therapy for Depression (COBRA): a randomised, controlled, non-inferiority trial
  7. 370407
    “…The ‘ChEMBL protein target slim’ is available as a browsable ‘Gene Ontology Tree’ on the ChEMBL site under the browse targets tab (https://www.ebi.ac.uk/chembl/target/browser). A ChEMBL protein target slim OBO file containing the GO slim terms pertinent to ChEMBL is available from the GOC website (http://geneontology.org/page/go-slim-and-subset-guide). …”
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    A drug target slim: using gene ontology and gene ontology annotations to navigate protein-ligand target space in ChEMBL
  8. 370408
    “…DESIGN: Multicentre prospective cohort study. SETTING: UK hospital and community settings. PARTICIPANTS INCLUSION: Consenting acutely ill patients aged ≥18 years, defined as high risk (Braden bedfast/chairfast AND completely immobile/very limited mobility; pressure area related pain or; category 1 PU). …”
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    Exploring the role of pain as an early predictor of category 2 pressure ulcers: a prospective cohort study
  9. 370409
    por Kar, Siddhartha P, Adler, Emily, Tyrer, Jonathan, Hazelett, Dennis, Anton-Culver, Hoda, Bandera, Elisa V, Beckmann, Matthias W, Berchuck, Andrew, Bogdanova, Natalia, Brinton, Louise, Butzow, Ralf, Campbell, Ian, Carty, Karen, Chang-Claude, Jenny, Cook, Linda S, Cramer, Daniel W, Cunningham, Julie M, Dansonka-Mieszkowska, Agnieszka, Doherty, Jennifer Anne, Dörk, Thilo, Dürst, Matthias, Eccles, Diana, Fasching, Peter A, Flanagan, James, Gentry-Maharaj, Aleksandra, Glasspool, Rosalind, Goode, Ellen L, Goodman, Marc T, Gronwald, Jacek, Heitz, Florian, Hildebrandt, Michelle A T, Høgdall, Estrid, Høgdall, Claus K, Huntsman, David G, Jensen, Allan, Karlan, Beth Y, Kelemen, Linda E, Kiemeney, Lambertus A, Kjaer, Susanne K, Kupryjanczyk, Jolanta, Lambrechts, Diether, Levine, Douglas A, Li, Qiyuan, Lissowska, Jolanta, Lu, Karen H, Lubiński, Jan, Massuger, Leon F A G, McGuire, Valerie, McNeish, Iain, Menon, Usha, Modugno, Francesmary, Monteiro, Alvaro N, Moysich, Kirsten B, Ness, Roberta B, Nevanlinna, Heli, Paul, James, Pearce, Celeste L, Pejovic, Tanja, Permuth, Jennifer B, Phelan, Catherine, Pike, Malcolm C, Poole, Elizabeth M, Ramus, Susan J, Risch, Harvey A, Rossing, Mary Anne, Salvesen, Helga B, Schildkraut, Joellen M, Sellers, Thomas A, Sherman, Mark, Siddiqui, Nadeem, Sieh, Weiva, Song, Honglin, Southey, Melissa, Terry, Kathryn L, Tworoger, Shelley S, Walsh, Christine, Wentzensen, Nicolas, Whittemore, Alice S, Wu, Anna H, Yang, Hannah, Zheng, Wei, Ziogas, Argyrios, Freedman, Matthew L, Gayther, Simon A, Pharoah, Paul D P, Lawrenson, Kate
    Publicado 2017
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    Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci
  10. 370410
    “…Data from amino acid analysis was aligned with glypican-3 (https://www.ebi.ac.uk/Tools/msa/clustalo/). The competitive reaction of mAb 1E4-1D9 and anti-glypican-3 on HepG2 cells was demonstrated by indirect immunofluorescence and analyzed by flow cytometry. …”
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    Characterization of a new monoclonal anti-glypican-3 antibody specific to the hepatocellular carcinoma cell line, HepG2
  11. 370411
    “…STUDY FUNDING/COMPETING INTEREST(S): H.O.D.C. received has clinical research support for laboratory consumables and staff from Bayer Pharma Ag and provides consultancy advice (no personal remuneration) for Bayer Pharma Ag, PregLem SA, Gedeon Richter, Vifor Pharma UK Ltd, AbbVie Inc.; A.R.W.W. has received consultancy payments from Bayer, Gedeon Richter, Preglem SA, HRA Pharma; L.H.R.W., A.A.M., R.M., G.S. and P.T.K.S. have no conflicts of interest. …”
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    Selective progesterone receptor modulator (SPRM) ulipristal acetate (UPA) and its effects on the human endometrium
  12. 370412
    “…FUNDING: Canadian Partnership Against Cancer, Cancer Focus Northern Ireland, Cancer Institute New South Wales, Cancer Research UK, US Centers for Disease Control and Prevention, Swiss Re, Swiss Cancer Research foundation, Swiss Cancer League, and the University of Kentucky.…”
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    Worldwide comparison of survival from childhood leukaemia for 1995–2009, by subtype, age, and sex (CONCORD-2): a population-based study of individual data for 89 828 children from 198 registries in 53 countries
  13. 370413
    Publicado 2017
    “…FUNDING: London School of Hygiene & Tropical Medicine, Pfizer, UK Department of Health, Wellcome Trust, and Bill & Melinda Gates Foundation.…”
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    Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial
  14. 370414
    “…Patients admitted to a hospital in Edinburgh, UK, after a suicide attempt were deemed eligible for the study if they were over the age of 16 years, had a self-reported history of self-harm, were fluent in English, were medically fit to interview, and were not participating in other research studies within the hospital. …”
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    A brief psychological intervention to reduce repetition of self-harm in patients admitted to hospital following a suicide attempt: a randomised controlled trial
  15. 370415
    “…FUNDING: National Prevention Research Initiative, Weight Watchers International (as part of an UK Medical Research Council Industrial Collaboration Award).…”
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    Extended and standard duration weight-loss programme referrals for adults in primary care (WRAP): a randomised controlled trial
  16. 370416
    “…Patients with PD were diagnosed by a neurologist with movement disorder training in accordance with the UK Parkinson’s Disease Society Brain Bank criteria. …”
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    Serotonin transporter binding and motor onset of Parkinson's disease in asymptomatic LRRK2 mutation carriers: a cross-sectional study
  17. 370417
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    Evaluating wait times from screening to breast cancer diagnosis among women undergoing organised assessment vs usual care
  18. 370418
    “…METHODS: In a prospective analysis of data acquired from four different adult inpatient and outpatient units of the South London and Maudsley Mental Health National Health Service Foundation Trust in London, UK, 245 patients were followed up for 2 years from the onset of first-episode psychosis. …”
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    Poor medication adherence and risk of relapse associated with continued cannabis use in patients with first-episode psychosis: a prospective analysis
  19. 370419
    “…We compared these treatments with those assessed in random samples of commercial and non-commercial clinical trials recruiting in the UK over the same period, which we identified using WHO’s International Clinical Trials Registry Platform. …”
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    Patients’, clinicians’ and the research communities’ priorities for treatment research: there is an important mismatch
  20. 370420
    por Mikami, Koichi, Sturdy, Steve
    Publicado 2017
    “…Finally, the consequences of Brexit for UK policies on rare diseases urgently need to be assessed. …”
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    Patient organization involvement and the challenge of securing access to treatments for rare diseases: report of a policy engagement workshop
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