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  1. 370741
    “…METHODS: A multi-country, one-wave, observational, cross-sectional, web-based, self-reported physician survey was conducted to assess the level of knowledge of key messages related to immune-related adverse drug reactions summarized in the atezolizumab HCP Guide and PAC among physicians (oncologists, pulmonologists, and urologists) prescribing atezolizumab in six European countries (Denmark, Germany, Italy, Spain, Sweden, and the UK). Responses regarding the receipt, understanding and use of the materials, and knowledge and behavior related to the HCP Guide and PAC are presented as percentages and continuous scores scaled out of 100 points, with corresponding 95% confidence intervals (CIs). …”
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    Effectiveness of Additional Risk Minimization Measures for Atezolizumab in the European Union
  2. 370742
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    The minor T allele of the MUC5B promoter rs35705950 associated with susceptibility to idiopathic pulmonary fibrosis: a meta-analysis
  3. 370743
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    Bioinformatics analysis of long non-coding RNA-associated competing endogenous RNA network in schizophrenia
  4. 370744
    “…DESIGN, SETTING, AND PARTICIPANTS: This multisite, double-blind, placebo-controlled, parallel-group randomized clinical trial from the UK examined adults 18 to 65 years of age within 3 years of a first presentation with a functional psychotic disorder who had no contraindication to vitamin D supplementation. …”
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    Effect of Vitamin D Supplementation on Outcomes in People With Early Psychosis: The DFEND Randomized Clinical Trial
  5. 370745
    “…METHODS: RIGHT-2 was a prospective, multicentre, paramedic-delivered, ambulance-based, sham-controlled, participant-and outcome-blinded, randomised-controlled trial of transdermal glyceryl trinitrate (GTN) in adults with ultra-acute presumed stroke in the UK. Final diagnosis (intracerebral haemorrhage, ischaemic stroke, transient ischaemic attack, mimic) was determined by the hospital investigator. …”
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    Pre-hospital transdermal glyceryl trinitrate in patients with stroke mimics: data from the RIGHT-2 randomised-controlled ambulance trial
  6. 370746
    “…DESIGN, SETTING, AND PARTICIPANTS: This large, single-nation, prospective cohort study was conducted among 276 patients with MOGAD at 5 health care centers in the UK. Data from January 1973 to March 2020 were collected from 146 patients at Oxford and its outreach sites, 65 patients at Liverpool, 32 patients at a children’s hospital in Birmingham, 22 patients at a children’s hospital in London, and 11 patients at Cardiff, Wales. …”
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    Factors Associated With Relapse and Treatment of Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease in the United Kingdom
  7. 370747
    “…A total of 2884 participants were assessed in studies across ten countries, with greatest output from North America (14 studies) and UK (six studies). Risk of bias was moderate to high for the majority of studies, mostly due to lack of participant blinding, which is not often practical for interventions of this nature. …”
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    Systematic review and meta-analysis of clinical effectiveness of self-management interventions in Parkinson’s disease
  8. 370748
    “…METHODS: We undertook a parallel-group cluster randomised trial, with nested test accuracy study and microbiological sub-study. UK maternity units were randomised to a strategy of rapid test (GeneXpert GBS system, Cepheid) or usual care. …”
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    Rapid intrapartum test for maternal group B streptococcal colonisation and its effect on antibiotic use in labouring women with risk factors for early-onset neonatal infection (GBS2): cluster randomised trial with nested test accuracy study
  9. 370749
    “…METHODS: Individuals ≥16 years old with new non-specific MSK symptoms and no clinical synovitis were recruited by primary care across the UK from July 2007 until May 2019. Those testing positive for the anti-CCP2 assay (anti-CCP+) were invited to Leeds for follow-up. …”
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    Prioritising referrals of individuals at-risk of RA: guidance based on results of a 10-year national primary care observational study
  10. 370750
    por Costa, Matthew L, Achten, Juul, Ooms, Alexander, Png, May Ee, Cook, Jonathan A, Lamb, Sarah E, Hedley, Helen, Dias, Joseph, Dritsaki, Melina, Dakin, Helen, Jones, Jonathan, Mckee, Andrew, Smith, Kevin, Hamadto, Mohamed, Gwilym, Steve, Chesser, Tim, Candal-Couto, Jaime, Hing, Caroline, Giddin, David, Johnston, Phil, Ullah, Aamer, Williams, John, Eardley, Will, Srinivasan, Makaram, Sampalli, Sridharrao, Farrar, Mark, Roberts, Chris, Mohanty, Khitish, MacLeod, Iain, Sarda, Praveen, Elseehy, Amr, Rossiter, Nigel, Warwick, David, Peach, Chris, MacKay, David, Benson, Richard, Watts, Adam, Young, Jonathan, Shah, Feisal, Lipscombe, Stephen, Ng, Aaron, Charalambous, Charalambos P, Sheriden, Barnaby, Theivendran, Kanthan, Sanjay, Pulimamidi, Nanda, Rajesh, Bateman, Antony, Butler, Michael, Keast-Butler, Oliver, McAndrew, Andrew, Chevannes, Wystan, Kankanalu, Pradeep, Wijendra, Asanka, Fontalis, Andreas, Afifi, Hytham, Killen, Marie-Clare, Higgin, Ryan, Wignadasan, Warran, Wong, Ken, Gibson, Catherine, Beale, Harry, Jennings, Bob, Kennedy, James, Williamson, Mark, Rasidovic, Damir, Jenner, Lydia, Tadros, John Baha, Milner, Steve, Duncan, James, Kerr, Sally, Nordin, Louise, Weston, Matt, Payton, Olivia, Oni, Tofi, Zhao, Craig, Gill, Sukhdeep, Iqbal, Mohammad, Killen, Marie-Clare, Aneiba, Khaled, Wignadasan, Warran, Pillai, Dilip, Hughes, Luke, Crosby, Jonathan, Whitehouse, Mike, Corbett, Thomas, Iqbal, Arshad, Buchan, Steph, Beddard, Laura, Vardhan, Venkat, Beamish, Becky, Jones, Matt, Holley, Jonathan, Morrell, Rebecca, Lerner, Robin, Draper, Kylea
    Publicado 2022
    “…DESIGN: Multicentre randomised clinical superiority trial, SETTING: 36 hospitals in the UK National Health Service (NHS). PARTICIPANTS: 500 adults aged 16 or over with a dorsally displaced fracture of the distal radius, randomised after manipulation of their fracture (255 to moulded cast; 245 to surgical fixation). …”
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    Surgical fixation with K-wires versus casting in adults with fracture of distal radius: DRAFFT2 multicentre randomised clinical trial
  11. 370751
    “…The systematic review was prospectively registered at PROSPERO (registration number CRD42019124734; available at: http://www.crd.york.ac.uk/prospero [accessed: 05 April 2019]). SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12887-021-03041-z.…”
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    Fat-free/lean body mass in children with insulin resistance or metabolic syndrome: a systematic review and meta-analysis
  12. 370752
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    Body mass index interacts with a genetic-risk score for depression increasing the risk of the disease in high-susceptibility individuals
  13. 370753
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    Evidence of plasma biomarkers indicating high risk of dementia in cognitively normal subjects
  14. 370754
    “…TRIAL REGISTRATION: PROSPERO CRD42020187551; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=187551 INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.1186/s13643-020-01479-3…”
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    Effectiveness of Live Health Professional–Led Group eHealth Interventions for Adult Mental Health: Systematic Review of Randomized Controlled Trials
  15. 370755
    por Mi, Xiao, Ippoliti, Matteo, Quintana, Chris, Greene, Ami, Chen, Zijun, Gross, Jonathan, Arute, Frank, Arya, Kunal, Atalaya, Juan, Babbush, Ryan, Bardin, Joseph C., Basso, Joao, Bengtsson, Andreas, Bilmes, Alexander, Bourassa, Alexandre, Brill, Leon, Broughton, Michael, Buckley, Bob B., Buell, David A., Burkett, Brian, Bushnell, Nicholas, Chiaro, Benjamin, Collins, Roberto, Courtney, William, Debroy, Dripto, Demura, Sean, Derk, Alan R., Dunsworth, Andrew, Eppens, Daniel, Erickson, Catherine, Farhi, Edward, Fowler, Austin G., Foxen, Brooks, Gidney, Craig, Giustina, Marissa, Harrigan, Matthew P., Harrington, Sean D., Hilton, Jeremy, Ho, Alan, Hong, Sabrina, Huang, Trent, Huff, Ashley, Huggins, William J., Ioffe, L. B., Isakov, Sergei V., Iveland, Justin, Jeffrey, Evan, Jiang, Zhang, Jones, Cody, Kafri, Dvir, Khattar, Tanuj, Kim, Seon, Kitaev, Alexei, Klimov, Paul V., Korotkov, Alexander N., Kostritsa, Fedor, Landhuis, David, Laptev, Pavel, Lee, Joonho, Lee, Kenny, Locharla, Aditya, Lucero, Erik, Martin, Orion, McClean, Jarrod R., McCourt, Trevor, McEwen, Matt, Miao, Kevin C., Mohseni, Masoud, Montazeri, Shirin, Mruczkiewicz, Wojciech, Naaman, Ofer, Neeley, Matthew, Neill, Charles, Newman, Michael, Niu, Murphy Yuezhen, O’Brien, Thomas E., Opremcak, Alex, Ostby, Eric, Pato, Balint, Petukhov, Andre, Rubin, Nicholas C., Sank, Daniel, Satzinger, Kevin J., Shvarts, Vladimir, Su, Yuan, Strain, Doug, Szalay, Marco, Trevithick, Matthew D., Villalonga, Benjamin, White, Theodore, Yao, Z. Jamie, Yeh, Ping, Yoo, Juhwan, Zalcman, Adam, Neven, Hartmut, Boixo, Sergio, Smelyanskiy, Vadim, Megrant, Anthony, Kelly, Julian, Chen, Yu, Sondhi, S. L., Moessner, Roderich, Kechedzhi, Kostyantyn, Khemani, Vedika, Roushan, Pedram
    Publicado 2021
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    Time-crystalline eigenstate order on a quantum processor
  16. 370756
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    The acute effect of fasted exercise on energy intake, energy expenditure, subjective hunger and gastrointestinal hormone release compared to fed exercise in healthy individuals: a systematic review and network meta-analysis
  17. 370757
    “…Study 3 (an online study of 2205 UK-representative adults) compared meal selections when participants were randomised to ranges comprised of (a) one meat-free, three meat options; (b) two meat-free, two meat; or (c) three meat-free, one meat. …”
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    Impact of increasing the relative availability of meat-free options on food selection: two natural field experiments and an online randomised trial
  18. 370758
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    miR-669a-5p promotes adipogenic differentiation and induces browning in preadipocytes
  19. 370759
    “…url=https%3A%2F%2Fwww.clinicaltrials.gov%2Fct2%2Fshow%2FNCT04719468%3Fterm%3DNCT04719468%26draw%3D2%26rank%3D1&data=04%7C01%7Crachel.davis%40kcl.ac.uk%7C11a7c5142782437919f808d903111449%7C8370cf1416f34c16b83c724071654356%7C0%7C0%7C6375441942616) (date of registration: 22 Jan 2021). (2) Melodies for Mums: NCT04834622 (https://clinicaltrials.gov/ct2/show/NCT04834622?…”
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    Study protocol: randomised controlled hybrid type 2 trial evaluating the scale-up of two arts interventions for postnatal depression and Parkinson’s disease
  20. 370760
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    The long noncoding RNA noncoding RNA activated by DNA damage (NORAD)-microRNA-496-Interleukin-33 axis affects carcinoma-associated fibroblasts-mediated gastric cancer development
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