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370781por Scrimshire, Ashley Brian, Booth, Alison, Fairhurst, Caroline, Coleman, Elizabeth, Malviya, Ajay, Kotze, Alwyn, Tiplady, Chris, Tate, David, Laverty, Annie, Davis, Gillian, Tadd, Win, Corbacho, Belen, Torgerson, David J., McDaid, Catriona, Reed, Mike“…BACKGROUND: The aim of this trial was to assess the effectiveness of quality improvement collaboratives to implement large-scale change in the National Health Service (NHS) in the UK, specifically for improving outcomes in patients undergoing primary, elective total hip or knee replacement. …”
Publicado 2022
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370782por Magnúsdóttir, Ingibjörg, Lovik, Anikó, Unnarsdóttir, Anna Bára, McCartney, Daniel, Ask, Helga, Kõiv, Kadri, Christoffersen, Lea Arregui Nordahl, Johnson, Sverre Urnes, Hauksdóttir, Arna, Fawns-Ritchie, Chloe, Helenius, Dorte, González-Hijón, Juan, Lu, Li, Ebrahimi, Omid V, Hoffart, Asle, Porteous, David J, Fang, Fang, Jakobsdóttir, Jóhanna, Lehto, Kelli, Andreassen, Ole A, Pedersen, Ole B V, Aspelund, Thor, Valdimarsdóttir, Unnur Anna“…METHODS: This observational follow-up study included seven prospectively planned cohorts across six countries (Denmark, Estonia, Iceland, Norway, Sweden, and the UK). Participants were recruited from March 27, 2020, to Aug 13, 2021. …”
Publicado 2022
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370783por Miller, Victoria, Reedy, Julia, Cudhea, Frederick, Zhang, Jianyi, Shi, Peilin, Erndt-Marino, Josh, Coates, Jennifer, Micha, Renata, Webb, Patrick, Mozaffarian, Dariush“…Among the 25 most populous countries in 2018, total ASF intake was highest in Russia (5·8 servings per day), Germany (3·8 servings per day), and the UK (3·7 servings per day), and lowest in Tanzania (0·9 servings per day) and India (0·7 servings per day). …”
Publicado 2022
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370784A cross-sectional study of factors associated with regular dog walking and intention to walk the dog“…METHODS: 191 dog-owning adults from a UK community were surveyed about their participation in dog walking, intention to dog walk, attitudes and behavioural beliefs regarding dog walking, and dog and owner demographics. …”
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370785
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370786por Kostka, Kristin, Duarte-Salles, Talita, Prats-Uribe, Albert, Sena, Anthony G, Pistillo, Andrea, Khalid, Sara, Lai, Lana Y H, Golozar, Asieh, Alshammari, Thamir M, Dawoud, Dalia M, Nyberg, Fredrik, Wilcox, Adam B, Andryc, Alan, Williams, Andrew, Ostropolets, Anna, Areia, Carlos, Jung, Chi Young, Harle, Christopher A, Reich, Christian G, Blacketer, Clair, Morales, Daniel R, Dorr, David A, Burn, Edward, Roel, Elena, Tan, Eng Hooi, Minty, Evan, DeFalco, Frank, de Maeztu, Gabriel, Lipori, Gigi, Alghoul, Hiba, Zhu, Hong, Thomas, Jason A, Bian, Jiang, Park, Jimyung, Martínez Roldán, Jordi, Posada, Jose D, Banda, Juan M, Horcajada, Juan P, Kohler, Julianna, Shah, Karishma, Natarajan, Karthik, Lynch, Kristine E, Liu, Li, Schilling, Lisa M, Recalde, Martina, Spotnitz, Matthew, Gong, Mengchun, Matheny, Michael E, Valveny, Neus, Weiskopf, Nicole G, Shah, Nigam, Alser, Osaid, Casajust, Paula, Park, Rae Woong, Schuff, Robert, Seager, Sarah, DuVall, Scott L, You, Seng Chan, Song, Seokyoung, Fernández-Bertolín, Sergio, Fortin, Stephen, Magoc, Tanja, Falconer, Thomas, Subbian, Vignesh, Huser, Vojtech, Ahmed, Waheed-Ul-Rahman, Carter, William, Guan, Yin, Galvan, Yankuic, He, Xing, Rijnbeek, Peter R, Hripcsak, George, Ryan, Patrick B, Suchard, Marc A, Prieto-Alhambra, Daniel“…PATIENTS AND METHODS: We conducted a descriptive retrospective database study using a federated network of data partners in the United States, Europe (the Netherlands, Spain, the UK, Germany, France and Italy) and Asia (South Korea and China). …”
Publicado 2022
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370787por Fraszczyk, Eliza, Spijkerman, Annemieke M. W., Zhang, Yan, Brandmaier, Stefan, Day, Felix R., Zhou, Li, Wackers, Paul, Dollé, Martijn E. T., Bloks, Vincent W., Gào, Xīn, Gieger, Christian, Kooner, Jaspal, Kriebel, Jennifer, Picavet, H. Susan J., Rathmann, Wolfgang, Schöttker, Ben, Loh, Marie, Verschuren, W. M. Monique, van Vliet-Ostaptchouk, Jana V., Wareham, Nicholas J., Chambers, John C., Ong, Ken K., Grallert, Harald, Brenner, Hermann, Luijten, Mirjam, Snieder, Harold“…Confirmation of genome-wide significant CpG sites was performed in a cohort of Indian Asians (LOLIPOP, UK). RESULTS: The meta-analysis identified 76 CpG sites that were differentially methylated in individuals with incident type 2 diabetes compared with control individuals (p values <1.1 × 10(−7)). …”
Publicado 2022
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370788por Zylstra, A. B., Hurricane, O. A., Callahan, D. A., Kritcher, A. L., Ralph, J. E., Robey, H. F., Ross, J. S., Young, C. V., Baker, K. L., Casey, D. T., Döppner, T., Divol, L., Hohenberger, M., Le Pape, S., Pak, A., Patel, P. K., Tommasini, R., Ali, S. J., Amendt, P. A., Atherton, L. J., Bachmann, B., Bailey, D., Benedetti, L. R., Berzak Hopkins, L., Betti, R., Bhandarkar, S. D., Biener, J., Bionta, R. M., Birge, N. W., Bond, E. J., Bradley, D. K., Braun, T., Briggs, T. M., Bruhn, M. W., Celliers, P. M., Chang, B., Chapman, T., Chen, H., Choate, C., Christopherson, A. R., Clark, D. S., Crippen, J. W., Dewald, E. L., Dittrich, T. R., Edwards, M. J., Farmer, W. A., Field, J. E., Fittinghoff, D., Frenje, J., Gaffney, J., Gatu Johnson, M., Glenzer, S. H., Grim, G. P., Haan, S., Hahn, K. D., Hall, G. N., Hammel, B. A., Harte, J., Hartouni, E., Heebner, J. E., Hernandez, V. J., Herrmann, H., Herrmann, M. C., Hinkel, D. E., Ho, D. D., Holder, J. P., Hsing, W. W., Huang, H., Humbird, K. D., Izumi, N., Jarrott, L. C., Jeet, J., Jones, O., Kerbel, G. D., Kerr, S. M., Khan, S. F., Kilkenny, J., Kim, Y., Geppert Kleinrath, H., Geppert Kleinrath, V., Kong, C., Koning, J. M., Kroll, J. J., Kruse, M. K. G., Kustowski, B., Landen, O. L., Langer, S., Larson, D., Lemos, N. C., Lindl, J. D., Ma, T., MacDonald, M. J., MacGowan, B. J., Mackinnon, A. J., MacLaren, S. A., MacPhee, A. G., Marinak, M. M., Mariscal, D. A., Marley, E. V., Masse, L., Meaney, K., Meezan, N. B., Michel, P. A., Millot, M., Milovich, J. L., Moody, J. D., Moore, A. S., Morton, J. W., Murphy, T., Newman, K., Di Nicola, J.-M. G., Nikroo, A., Nora, R., Patel, M. V., Pelz, L. J., Peterson, J. L., Ping, Y., Pollock, B. B., Ratledge, M., Rice, N. G., Rinderknecht, H., Rosen, M., Rubery, M. S., Salmonson, J. D., Sater, J., Schiaffino, S., Schlossberg, D. J., Schneider, M. B., Schroeder, C. R., Scott, H. A., Sepke, S. M., Sequoia, K., Sherlock, M. W., Shin, S., Smalyuk, V. A., Spears, B. K., Springer, P. T., Stadermann, M., Stoupin, S., Strozzi, D. J., Suter, L. J., Thomas, C. A., Town, R. P. J., Tubman, E. R., Trosseille, C., Volegov, P. L., Weber, C. R., Widmann, K., Wild, C., Wilde, C. H., Van Wonterghem, B. M., Woods, D. T., Woodworth, B. N., Yamaguchi, M., Yang, S. T., Zimmerman, G. B.Enlace del recurso
Publicado 2022
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370789por Blackman, Jonathan, Love, Seth, Sinclair, Lindsey, Cain, Richard, Coulthard, Elizabeth“…METHODS: This retrospective cohort study used UK Brain Banks Network data. Eligible subjects were aged over 50, with pre-mortem neuropsychiatry inventory scores of sleep disturbance (NPI-K), neurocognitive testing and functional cognitive status assessment (Clinical Dementia Rating scale). …”
Publicado 2022
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370790por Clarkson, Jan E., Ramsay, Craig R., Mannocci, Francesco, Jarad, Fadi, Albadri, Sondos, Ricketts, David, Tait, Carol, Banerjee, Avijit, Deery, Chris, Boyers, Dwayne, Marshman, Zoe, Goulao, Beatriz, Hamilton, Alice R., Banister, Katie, Bell, Rosanne, Brown, Lori, Conway, David I., Donaldson, Pina, Duncan, Anne, Dunn, Katharine, Fee, Patrick, Forrest, Mark, Glenny, Anne-Marie, Gouick, Jill, Gupta, Ekta, Jacobsen, Elisabet, Kettle, Jennifer, MacLennan, Graeme, Macpherson, Lorna, McGuff, Tina, Mitchell, Fiona, van der Pol, Marjon, Moazzez, Rebecca, Roberston, Douglas, Wojewodka, Gabriella, Young, Linda, Lamont, Thomas“…Although this technique may be provided in secondary care, it has not been routinely implemented or evaluated in UK General Dental Practice. METHOD: This feasibility study aims to identify and assess in a primary care setting the training needs of general dental practitioners and clinical fidelity of the full pulpotomy intervention, estimate likely eligible patient pool and develop recruitment materials ahead of the main randomised controlled trial comparing the clinical and cost-effectiveness of full pulpotomy compared to root canal treatment in pre/molar teeth of adults 16 years and older showing signs indicative of irreversible pulpitis. …”
Publicado 2022
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370791por Lee, Ming Jie, Collins, Simon, Babalis, Daphne, Johnson, Nicholas, Falaschetti, Emanuela, Prevost, A. Toby, Ashraf, Ambreen, Jacob, Milaana, Cole, Tom, Hurley, Lisa, Pace, Matthew, Ogbe, Ane, Khan, Maryam, Zacharopoulou, Panagiota, Brown, Helen, Sutherland, Euan, Box, Hanna, Fox, Julie, Deeks, Steven, Horowitz, Jill, Nussenzweig, Michel C., Caskey, Marina, Frater, John, Fidler, Sarah“…TRIAL REGISTRATION: The protocol is registered on Clinical.trials.gov and EudraCT and has approval from UK Ethics and MHRA. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13063-022-06151-w.…”
Publicado 2022
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370792por Nakao, Tetsushi, Bick, Alexander G., Taub, Margaret A., Zekavat, Seyedeh M., Uddin, Md M., Niroula, Abhishek, Carty, Cara L., Lane, John, Honigberg, Michael C., Weinstock, Joshua S., Pampana, Akhil, Gibson, Christopher J., Griffin, Gabriel K., Clarke, Shoa L., Bhattacharya, Romit, Assimes, Themistocles L., Emery, Leslie S., Stilp, Adrienne M., Wong, Quenna, Broome, Jai, Laurie, Cecelia A., Khan, Alyna T., Smith, Albert V., Blackwell, Thomas W., Codd, Veryan, Nelson, Christopher P., Yoneda, Zachary T., Peralta, Juan M., Bowden, Donald W., Irvin, Marguerite R., Boorgula, Meher, Zhao, Wei, Yanek, Lisa R., Wiggins, Kerri L., Hixson, James E., Gu, C. Charles, Peloso, Gina M., Roden, Dan M., Reupena, Muagututi’a S., Hwu, Chii-Min, DeMeo, Dawn L., North, Kari E., Kelly, Shannon, Musani, Solomon K., Bis, Joshua C., Lloyd-Jones, Donald M., Johnsen, Jill M., Preuss, Michael, Tracy, Russell P., Peyser, Patricia A., Qiao, Dandi, Desai, Pinkal, Curran, Joanne E., Freedman, Barry I., Tiwari, Hemant K., Chavan, Sameer, Smith, Jennifer A., Smith, Nicholas L., Kelly, Tanika N., Hidalgo, Bertha, Cupples, L. Adrienne, Weeks, Daniel E., Hawley, Nicola L., Minster, Ryan L., Deka, Ranjan, Naseri, Take T., de las Fuentes, Lisa, Raffield, Laura M., Morrison, Alanna C., Vries, Paul S., Ballantyne, Christie M., Kenny, Eimear E., Rich, Stephen S., Whitsel, Eric A., Cho, Michael H., Shoemaker, M. Benjamin, Pace, Betty S., Blangero, John, Palmer, Nicholette D., Mitchell, Braxton D., Shuldiner, Alan R., Barnes, Kathleen C., Redline, Susan, Kardia, Sharon L.R., Abecasis, Gonçalo R., Becker, Lewis C., Heckbert, Susan R., He, Jiang, Post, Wendy, Arnett, Donna K., Vasan, Ramachandran S., Darbar, Dawood, Weiss, Scott T., McGarvey, Stephen T., de Andrade, Mariza, Chen, Yii-Der Ida, Kaplan, Robert C., Meyers, Deborah A., Custer, Brian S., Correa, Adolfo, Psaty, Bruce M., Fornage, Myriam, Manson, JoAnn E., Boerwinkle, Eric, Konkle, Barbara A., Loos, Ruth J.F., Rotter, Jerome I., Silverman, Edwin K., Kooperberg, Charles, Danesh, John, Samani, Nilesh J., Jaiswal, Siddhartha, Libby, Peter, Ellinor, Patrick T., Pankratz, Nathan, Ebert, Benjamin L., Reiner, Alexander P., Mathias, Rasika A., Do, Ron, Natarajan, Pradeep“…Here, we investigated the relationship between CHIP, LTL, and CAD in the Trans-Omics for Precision Medicine (TOPMed) program (n = 63,302) and UK Biobank (n = 47,080). Bidirectional Mendelian randomization studies were consistent with longer genetically imputed LTL increasing propensity to develop CHIP, but CHIP then, in turn, hastens to shorten measured LTL (mLTL). …”
Publicado 2022
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370793por Rosa, Nicolas, Ivanova, Hristina, Wagner, Larry E., Kale, Justin, La Rovere, Rita, Welkenhuyzen, Kirsten, Louros, Nikolaos, Karamanou, Spyridoula, Shabardina, Victoria, Lemmens, Irma, Vandermarliere, Elien, Hamada, Kozo, Ando, Hideaki, Rousseau, Frederic, Schymkowitz, Joost, Tavernier, Jan, Mikoshiba, Katsuhiko, Economou, Anastassios, Andrews, David W., Parys, Jan B., Yule, David I., Bultynck, GeertEnlace del recurso
Publicado 2021
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370794por Sanooghi, Davood, Lotfi, Abolfazl, Bagher, Zohreh, Barati, Shirin, Karimi, Afzal, Faghihi, Faezeh, Lotfi, Erfan, Joghataei, Mohammad TaghiEnlace del recurso
Publicado 2022
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370795por Menni, Cristina, May, Anna, Polidori, Lorenzo, Louca, Panayiotis, Wolf, Jonathan, Capdevila, Joan, Hu, Christina, Ourselin, Sebastien, Steves, Claire J, Valdes, Ana M, Spector, Tim D“…We aimed to investigate COVID-19 primary vaccine series effectiveness and its waning, and the safety and effectiveness of booster doses, in a UK community setting. METHODS: We used SARS-CoV-2 positivity rates in individuals from a longitudinal, prospective, community-based study (ZOE COVID Study), in which data were self-reported through an app, to assess the effectiveness of three COVID-19 vaccines (ChAdOx1 nCov19 [Oxford-AstraZeneca], BNT162b2 [Pfizer-BioNtech], and mRNA1273 [Moderna]) against infection in the 8 months after completion of primary vaccination series. …”
Publicado 2022
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370796por Wilairatana, Polrat, Mala, Wanida, Milanez, Giovanni De Jesus, Masangkay, Frederick Ramirez, Kotepui, Kwuntida Uthaisar, Kotepui, ManasEnlace del recurso
Publicado 2022
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370797“…RESULTS: Nine publications covering eight unique studies met all eligibility criteria for inclusion in the SLR, including four conference abstracts, two peer-reviewed original research articles and three HTA submissions (conducted in Canada, the US and the UK). Evaluations considered patients with early infantile-onset (most likely to develop Type 1 or Type 2 SMA), later-onset SMA and both infantile- and later-onset SMA. …”
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370798por Heald, Adrian H., Jenkins, David A., Williams, Richard, Sperrin, Matthew, Mudaliar, Rajshekhar N., Syed, Akheel, Naseem, Asma, Bowden Davies, Kelly A., Peng, Yonghong, Peek, Niels, Ollier, William, Anderson, Simon G., Delanerolle, Gayathri, Gibson, J. Martin“…This was conducted as an urban population study and based in the UK. METHODS: Analysis of electronic health record data was performed relating to people living in the Greater Manchester conurbation (population 2.82 million) who had a recorded diagnosis of T2DM and subsequent COVID-19 confirmed infection. …”
Publicado 2022
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370799por Wang, Xiaoliang, Kapoor, Pooja Middha, Auer, Paul L., Dennis, Joe, Dunning, Alison M., Wang, Qin, Lush, Michael, Michailidou, Kyriaki, Bolla, Manjeet K., Aronson, Kristan J., Murphy, Rachel A., Brooks-Wilson, Angela, Lee, Derrick G., Cordina-Duverger, Emilie, Guénel, Pascal, Truong, Thérèse, Mulot, Claire, Teras, Lauren R., Patel, Alpa V., Dossus, Laure, Kaaks, Rudolf, Hoppe, Reiner, Lo, Wing-Yee, Brüning, Thomas, Hamann, Ute, Czene, Kamila, Gabrielson, Marike, Hall, Per, Eriksson, Mikael, Jung, Audrey, Becher, Heiko, Couch, Fergus J., Larson, Nicole L., Olson, Janet E., Ruddy, Kathryn J., Giles, Graham G., MacInnis, Robert J., Southey, Melissa C., Le Marchand, Loic, Wilkens, Lynne R., Haiman, Christopher A., Olsson, Håkan, Augustinsson, Annelie, Krüger, Ute, Wagner, Philippe, Scott, Christopher, Winham, Stacey J., Vachon, Celine M., Perou, Charles M., Olshan, Andrew F., Troester, Melissa A., Hunter, David J., Eliassen, Heather A., Tamimi, Rulla M., Brantley, Kristen, Andrulis, Irene L., Figueroa, Jonine, Chanock, Stephen J., Ahearn, Thomas U., García-Closas, Montserrat, Evans, Gareth D., Newman, William G., van Veen, Elke M., Howell, Anthony, Wolk, Alicja, Håkansson, Niclas, Anton-Culver, Hoda, Ziogas, Argyrios, Jones, Michael E., Orr, Nick, Schoemaker, Minouk J., Swerdlow, Anthony J., Kitahara, Cari M., Linet, Martha, Prentice, Ross L., Easton, Douglas F., Milne, Roger L., Kraft, Peter, Chang-Claude, Jenny, Lindström, SaraEnlace del recurso
Publicado 2022
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370800por Zhan, Qionghui, Jeon, Jaepyo, Li, Ying, Huang, Yu, Xiong, Jian, Wang, Qiaochu, Xu, Tian-Le, Li, Yong, Ji, Fu-Hai, Du, Guangwei, Zhu, Michael XEnlace del recurso
Publicado 2021
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