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370881“…We extracted estimates of association and variance from qualifying studies and augmented these findings with analyses of unpublished data from individual participants in two UK birth cohorts—ie, the 1958 and 1970 studies (total n=21 936). …”
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370882por Zhang, Yuan, Yang, Rongrong, Hou, Yabing, Chen, Yanchun, Li, Shu, Wang, Yaogang, Yang, Hongxi“…METHODS: This prospective cohort study included 33,236 participants (aged 40–72) with type 2 diabetes from the UK Biobank with annual follow-up from 2006 to 2010 to 2020. …”
Publicado 2022
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370883por Woloschak, Michael, Miller, Jennifer, Felner, Eric, Bird, Lynne, Angulo, Moris, Mejia-Corletto, Jorge, Gevers, Evelien, Shoemaker, Ashley, Yanovski, Jack, Butler, Merlin, Salehi, Parisa, Stevenson, David, Wilding, John, Abuzzahab, Jennifer, Konczal, Laura, Guftar Shaikh, M, Viskochil, David, Lah, Melissa, Mathew, Verghese, Yen, Kristen, Bhatnagar, Anish, Obrynba, Kathryn“…OBJECTIVES AND METHODS: The objective was to evaluate long-term safety of DCCR in individuals with PWS. 125 participants with genetically-confirmed PWS ≥4 years old with hyperphagia were treated with oral daily DCCR in multi-center studies conducted at 29 sites in the US and the UK: a 13-week, Phase 3, double-blind, placebo-controlled study (DESTINY PWS) and its long-term, open-label extension study (to 52 weeks and beyond). …”
Publicado 2022
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370884por Chan, Li, Smith, Chris, Read, Jordan, Hall, Charlotte, Maharaj, Avinaash, Ramirez, Lucia Marroquin, Qamar, Younus, Hughes, Claire, Clark, Adrian, Musa, Salwa, Prasad, Rathi, Metherell, Lou“…Examples include the previously described S74I in MC2R and rs6161 in CYP11A1 in the UK population, P24Rfs*4 in MCM4 in Ireland, R188C in STAR in Canada, and newly discovered associations with T731= in NNT in Sudan and R222Q in SGPL1 in Saudi Arabia. …”
Publicado 2022
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370885por Merke, Deborah P, Mallappa, Ashwini, Arlt, Wiebke, De La Perriere, Aude Brac, Hirschberg, Angelica Linden, Juul, Anders, Newell-Price, John D C, Perry, Colin G, Prete, Alessandro, Rees, Aled, Reisch, Nicole, Stikkelbroeck, Monica, Touraine, Philippe A, Coope, Helen J, Porter, John, Ross, Richard J“…Modified-release hydrocortisone (MRHC) capsules, (Efmody, Diurnal Ltd, Cardiff UK), replicate the cortisol diurnal rhythm and improve the control of CAH compared to standard glucocorticoid therapy(3). …”
Publicado 2022
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370886por Turkova, Anna, Waalewijn, Hylke, Chan, Man K, Bollen, Pauline D J, Bwakura-Dangarembizi, Mutsa F, Kekitiinwa, Adeodata R, Cotton, Mark F, Lugemwa, Abbas, Variava, Ebrahim, Ahimbisibwe, Grace Miriam, Srirompotong, Ussanee, Mumbiro, Vivian, Amuge, Pauline, Zuidewind, Peter, Ali, Shabinah, Kityo, Cissy M, Archary, Moherndran, Ferrand, Rashida A, Violari, Avy, Gibb, Diana M, Burger, David M, Ford, Deborah, Colbers, Angela“…FUNDING: Penta Foundation, ViiV Healthcare, UK Medical Research Council.…”
Publicado 2022
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370887por Pakvisal, Nussara, Kongkavitoon, Pornrat, Sathitruangsak, Chirawadee, Pornpattanarak, Nopporn, Boonsirikamchai, Piyaporn, Ouwongprayoon, Pongsakorn, Aporntewan, Chatchawit, Chantranuwatana, Poonchavist, Mutirangura, Apiwat, Vinayanuwattikun, ChanidaEnlace del recurso
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370888por Homan, Tobias, Mazzilli, Sara, Chieti, Antonio, Musa, Alessandra, Roth, Adam, Fortunato, Francesca, Bisceglia, Lucia, Prato, Rosa, Lopalco, Pier Luigi, Martinelli, DomenicoEnlace del recurso
Publicado 2022
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370889por Charland, Nathalie, Gobeil, Philipe, Pillet, Stéphane, Boulay, Iohann, Séguin, Annie, Makarkov, Alexander, Heizer, Gretchen, Bhutada, Kapil, Mahmood, Asif, Trépanier, Sonia, Hager, Karen, Jiang-Wright, Julia, Atkins, Judith, Saxena, Pooja, Cheng, Matthew P., Vinh, Donald C., Boutet, Philippe, Roman, François, Van Der Most, Robbert, Ceregido, Maria Angeles, Dionne, Marc, Tellier, Guy, Gauthier, Jean-Sébastien, Essink, Brandon, Libman, Michael, Haffizulla, Jason, Fréchette, André, D’Aoust, Marc-André, Landry, Nathalie, Ward, Brian J.Enlace del recurso
Publicado 2022
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370890
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370891por Marcus, Elena, Latos-Bielenska, Anna, Jamry-Dziurla, Anna, Barišić, Ingeborg, Cavero-Carbonell, Clara, Den Hond, Elly, Garne, Ester, Genard, Lucas, Santos, Ana João, Lutke, LRenée, Matias Dias, Carlos, Neergaard Pedersen, Christina, Neville, Amanda J., Niemann, Annika, Odak, Ljubica, Pierini, Anna, Rico, Juan, Rissmann, Anke, Rankin, Judith, Morris, Joan K.“…RESULTS: One thousand seventy parents/carers of children with a cleft lip (n = 247), spina bifida (n = 118), CHD (n = 366), Down syndrome (n = 281), and Down syndrome with CHD (n = 58) were recruited in Poland (n = 476), the UK (n = 120), Germany (n = 97), the Netherlands/Belgium (n = 74), Croatia (n = 68), Italy (n = 59), other European countries (n = 92), and not specified/non-European countries (n = 84). …”
Publicado 2022
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370892por Lucas, Joana, Costa, Eduardo, Subtil, Ana, Sequeira, Rita, Campos Fernandes, Adalberto, Robalo Nunes, António, Sousa, PauloEnlace del recurso
Publicado 2022
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370893por Goldberg, Andrew J., Chowdhury, Kashfia, Molloy, Andrew P., Davies, Mark Bowen, Hepple, Steve, Thomas, Rhys H., Siddique, Malik S., Loveday, David T., Dhar, Sunil, Bing, Andrew J., Clough, Timothy, Bendall, Stephen P., Rogers, Mark, Milner, Stephen, Mishra, Viren, Butler, Michael, Halliwell, Paul, Townshend, David N.“…Patients with EOA, aged 50-85, suitable for either procedure were recruited at 17 UK hospitals. Randomisation was carried out using a secure on-line service and was stratified by surgeon and the presence or absence of adjacent joint OA (based on an independently reviewed preoperative MRI scan). …”
Publicado 2022
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370894por Dillon, Richard, Maycock, Shanna, Jackson, Aimee, Fox, Sonia, Freeman, Sylvie, Craddock, Charles, Thomas, Catherine, Homer, Emma, Leahy, Jane, Mamwell, Anna, Potter, Nicola, Russell, Nigel, Wei, Andrew, Ommen, Hans Beier, Hemmaway, Claire, Knapper, Steve, Billingham, Lucinda“…University of Birmingham is the UK co-ordinating centre, with national hubs in Aarhus University Hospital, Denmark, and Auckland District Health Board, New Zealand. …”
Publicado 2022
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370895por Shetty, Ashish, Delanerolle, Gayathri, Zeng, Yutian, Shi, Jian Qing, Ebrahim, Rawan, Pang, Joanna, Hapangama, Dharani, Sillem, Martin, Shetty, Suchith, Shetty, Balakrishnan, Hirsch, Martin, Raymont, Vanessa, Majumder, Kingshuk, Chong, Sam, Goodison, William, O’Hara, Rebecca, Hull, Louise, Pluchino, Nicola, Shetty, Naresh, Elneil, Sohier, Fernandez, Tacson, Brownstone, Robert M., Phiri, Peter“…SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/prospero/, identifier: CRD42021228343.…”
Publicado 2022
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370896por Jarvis, Erich D., Formenti, Giulio, Rhie, Arang, Guarracino, Andrea, Yang, Chentao, Wood, Jonathan, Tracey, Alan, Thibaud-Nissen, Francoise, Vollger, Mitchell R., Porubsky, David, Cheng, Haoyu, Asri, Mobin, Logsdon, Glennis A., Carnevali, Paolo, Chaisson, Mark J. P., Chin, Chen-Shan, Cody, Sarah, Collins, Joanna, Ebert, Peter, Escalona, Merly, Fedrigo, Olivier, Fulton, Robert S., Fulton, Lucinda L., Garg, Shilpa, Gerton, Jennifer L., Ghurye, Jay, Granat, Anastasiya, Green, Richard E., Harvey, William, Hasenfeld, Patrick, Hastie, Alex, Haukness, Marina, Jaeger, Erich B., Jain, Miten, Kirsche, Melanie, Kolmogorov, Mikhail, Korbel, Jan O., Koren, Sergey, Korlach, Jonas, Lee, Joyce, Li, Daofeng, Lindsay, Tina, Lucas, Julian, Luo, Feng, Marschall, Tobias, Mitchell, Matthew W., McDaniel, Jennifer, Nie, Fan, Olsen, Hugh E., Olson, Nathan D., Pesout, Trevor, Potapova, Tamara, Puiu, Daniela, Regier, Allison, Ruan, Jue, Salzberg, Steven L., Sanders, Ashley D., Schatz, Michael C., Schmitt, Anthony, Schneider, Valerie A., Selvaraj, Siddarth, Shafin, Kishwar, Shumate, Alaina, Stitziel, Nathan O., Stober, Catherine, Torrance, James, Wagner, Justin, Wang, Jianxin, Wenger, Aaron, Xiao, Chuanle, Zimin, Aleksey V., Zhang, Guojie, Wang, Ting, Li, Heng, Garrison, Erik, Haussler, David, Hall, Ira, Zook, Justin M., Eichler, Evan E., Phillippy, Adam M., Paten, Benedict, Howe, Kerstin, Miga, Karen H.Enlace del recurso
Publicado 2022
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370897por Iriondo, Marina N., Etxaniz, Asier, Varela, Yaiza R., Ballesteros, Uxue, Hervás, Javier H., Montes, L. Ruth, Goñi, Félix M., Alonso, AliciaEnlace del recurso
Publicado 2022
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370898
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370899
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370900por Liodakis, Ioannis, Marscher, Alan P., Agudo, Iván, Berdyugin, Andrei V., Bernardos, Maria I., Bonnoli, Giacomo, Borman, George A., Casadio, Carolina, Casanova, Víctor, Cavazzuti, Elisabetta, Rodriguez Cavero, Nicole, Di Gesu, Laura, Di Lalla, Niccoló, Donnarumma, Immacolata, Ehlert, Steven R., Errando, Manel, Escudero, Juan, García-Comas, Maya, Agís-González, Beatriz, Husillos, César, Jormanainen, Jenni, Jorstad, Svetlana G., Kagitani, Masato, Kopatskaya, Evgenia N., Kravtsov, Vadim, Krawczynski, Henric, Lindfors, Elina, Larionova, Elena G., Madejski, Grzegorz M., Marin, Frédéric, Marchini, Alessandro, Marshall, Herman L., Morozova, Daria A., Massaro, Francesco, Masiero, Joseph R., Mawet, Dimitri, Middei, Riccardo, Millar-Blanchaer, Maxwell A., Myserlis, Ioannis, Negro, Michela, Nilsson, Kari, O’Dell, Stephen L., Omodei, Nicola, Pacciani, Luigi, Paggi, Alessandro, Panopoulou, Georgia V., Peirson, Abel L., Perri, Matteo, Petrucci, Pierre-Olivier, Poutanen, Juri, Puccetti, Simonetta, Romani, Roger W., Sakanoi, Takeshi, Savchenko, Sergey S., Sota, Alfredo, Tavecchio, Fabrizio, Tinyanont, Samaporn, Vasilyev, Andrey A., Weaver, Zachary R., Zhovtan, Alexey V., Antonelli, Lucio A., Bachetti, Matteo, Baldini, Luca, Baumgartner, Wayne H., Bellazzini, Ronaldo, Bianchi, Stefano, Bongiorno, Stephen D., Bonino, Raffaella, Brez, Alessandro, Bucciantini, Niccoló, Capitanio, Fiamma, Castellano, Simone, Ciprini, Stefano, Costa, Enrico, De Rosa, Alessandra, Del Monte, Ettore, Di Marco, Alessandro, Doroshenko, Victor, Dovčiak, Michal, Enoto, Teruaki, Evangelista, Yuri, Fabiani, Sergio, Ferrazzoli, Riccardo, Garcia, Javier A., Gunji, Shuichi, Hayashida, Kiyoshi, Heyl, Jeremy, Iwakiri, Wataru, Karas, Vladimir, Kitaguchi, Takao, Kolodziejczak, Jeffery J., La Monaca, Fabio, Latronico, Luca, Maldera, Simone, Manfreda, Alberto, Marinucci, Andrea, Matt, Giorgio, Mitsuishi, Ikuyuki, Mizuno, Tsunefumi, Muleri, Fabio, Ng, Stephen C.-Y., Oppedisano, Chiara, Papitto, Alessandro, Pavlov, George G., Pesce-Rollins, Melissa, Pilia, Maura, Possenti, Andrea, Ramsey, Brian D., Rankin, John, Ratheesh, Ajay, Sgró, Carmelo, Slane, Patrick, Soffitta, Paolo, Spandre, Gloria, Tamagawa, Toru, Taverna, Roberto, Tawara, Yuzuru, Tennant, Allyn F., Thomas, Nicolas E., Tombesi, Francesco, Trois, Alessio, Tsygankov, Sergey, Turolla, Roberto, Vink, Jacco, Weisskopf, Martin C., Wu, Kinwah, Xie, Fei, Zane, SilviaEnlace del recurso
Publicado 2022
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