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1481por Diamantopoulos, Alex, Finckh, A., Huizinga, T., Sungher, D. K., Sawyer, L., Neto, D., Dejonckheere, F.“…BACKGROUND: Since receiving a positive recommendation in England, Wales and Scotland, tocilizumab (TCZ) is one of the options available to clinicians for the treatment of rheumatoid arthritis (RA) patients in the UK. OBJECTIVE: The objective of this study was to evaluate the cost effectiveness of adding TCZ to the current treatment sequence of RA patients from a UK payer’s perspective over a patient lifetime horizon. …”
Publicado 2014
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1482
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1483por Hunt, Elizabeth J. F., Wessely, Simon, Jones, Norman, Rona, Roberto J., Greenberg, Neil“…A substantial amount of research has been conducted into the mental health of the UK military in recent years. This article summarises the results of the various studies and offers possible explanations for differences in findings between the UK and other allied nations. …”
Publicado 2014
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1484
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1485“…RATIONALE: To assess the treatment progression during the 24 months following a formal diagnosis of chronic obstructive pulmonary disease (COPD) in the UK primary care setting. METHODS: A retrospective cohort of newly diagnosed COPD patients was identified in the Clinical Practice Research Datalink (CPRD) from 1/1/2008 until 31/12/2009. …”
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1486por Duong, Trinh, Judd, Ali, Collins, Intira Jeannie, Doerholt, Katja, Lyall, Hermione, Foster, Caroline, Butler, Karina, Tookey, Pat, Shingadia, Delane, Menson, Esse, Dunn, David T., Gibb, Di M.“…METHODS: Factors associated with viral load below 400 copies/ml by 12 months and virologic failure among children starting 3/4-drug ART in the UK/Irish Collaborative HIV Paediatric Study were assessed using Poisson models. …”
Publicado 2014
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1487“…Our aim in this paper is to report on the topics that this senior cohort of UK-trained doctors who work in UK medicine raised with us. …”
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1488“…BACKGROUND: The UK National Health Service (NHS) is undergoing institutional reorganisation due to the Health and Social Care Act-2012 with a continued restriction on funding within the NHS and clinically focused academic institutions. …”
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1489“…METHODS: To explore the commitment, experience and attitudes of clinical teachers and trainers of undergraduate medical students and postgraduate trainees, respectively, amongst secondary care providers across a UK Healthcare Workforce Deanery, an invitation to complete a study-specific, on-line survey, comprising predominantly yes/no response and 5-point Likert scale statements with some open questions, was sent to all registered secondary care trainers/supervisors working in the East Midlands Strategic Health Authority. …”
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1490por Dunn, Warwick B., Lin, Wanchang, Broadhurst, David, Begley, Paul, Brown, Marie, Zelena, Eva, Vaughan, Andrew A., Halsall, Antony, Harding, Nadine, Knowles, Joshua D., Francis-McIntyre, Sue, Tseng, Andy, Ellis, David I., O’Hagan, Steve, Aarons, Gill, Benjamin, Boben, Chew-Graham, Stephen, Moseley, Carly, Potter, Paula, Winder, Catherine L., Potts, Catherine, Thornton, Paula, McWhirter, Catriona, Zubair, Mohammed, Pan, Martin, Burns, Alistair, Cruickshank, J. Kennedy, Jayson, Gordon C., Purandare, Nitin, Wu, Frederick C. W., Finn, Joe D., Haselden, John N., Nicholls, Andrew W., Wilson, Ian D., Goodacre, Royston, Kell, Douglas B.“…Phenotyping of 1,200 ‘healthy’ adults from the UK has been performed through the investigation of diverse classes of hydrophilic and lipophilic metabolites present in serum by applying a series of chromatography–mass spectrometry platforms. …”
Publicado 2014
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1492
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1493por Vaux, Alexander GC, Gibson, Gabriella, Hernandez-Triana, Luis M, Cheke, Robert A, McCracken, Fiona, Jeffries, Claire L, Horton, Daniel L, Springate, Simon, Johnson, Nicholas, Fooks, Anthony R, Leach, Steve, Medlock, Jolyon M“…BACKGROUND: As part of efforts to more fully understand the potential risks posed by West Nile virus (WNV) and Usutu virus (USUV) in the UK, and following on from previous reports of a potential bridge vector Culex modestus for these viruses, at wetland sites in North Kent, mosquito surveillance was undertaken more widely across the Isle of Sheppey, the Hoo Peninsula and the Kent mainland. …”
Publicado 2015
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1494por Munang, Melinda L., Browne, Catherine, Khanom, Shaina, Evans, Jason T., Smith, E. Grace, Hawkey, Peter M., Kunst, Heinke, Welch, Steven B., Dedicoat, Martin J.“…To determine if local transmission was responsible for rising tuberculosis incidence in a recently dispersed migrant community in Birmingham, UK, during 2004–2013, we conducted enhanced epidemiologic investigation of molecular clusters. …”
Publicado 2015
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1495por Kelly, Susan E., Spector, Timothy D., Cherkas, Lynn F., Prainsack, Barbara, Harris, Juliette M.“…DESIGN, SETTING AND PARTICIPANTS: 2,308 adult volunteers from the TwinsUK Registry (www.twinsuk.ac.uk) completed an online survey about their views on the consent process for use of their DNA and medical information in research. …”
Publicado 2015
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1496por Mourad, Moustafa Mabrouk, Liossis, Christos, Algarni, Abdullah, Kumar, Senthil, Bramhall, Simon R.“…Primary hepatic tuberculosis (TB) is very rare in the UK, but the incidence may be rising. Three cases of primary hepatic TB in immunocompetent patients without evidence of pulmonary involvement are reported. …”
Publicado 2014
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1497por Lenox-Smith, Alan, Macdonald, Mark T. B., Reed, Catherine, Tylee, Andre, Peveler, Robert, Quail, Deborah, Wildgust, Hiram J.“…This paper examines primary care patients recruited in the UK. HRQoL was measured at baseline and at 3 and 6 months after starting antidepressant therapy using the Short Form 36 Health Status Survey and the European Quality of Life-5 Dimensions (EQ-5D). …”
Publicado 2013
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1499por Milner, James, Green, Rosemary, Dangour, Alan D, Haines, Andy, Chalabi, Zaid, Spadaro, Joseph, Markandya, Anil, Wilkinson, Paul“…This study attempted to quantify the health effects associated with adopting low GHG emission diets in the UK. DESIGN: Epidemiological modelling study. SETTING: UK. …”
Publicado 2015
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1500“…A number of significant changes were made to the UK immunisation schedule for 2013/2014. Three new vaccines were introduced: intranasal influenza and oral rotavirus for children and subcutaneous shingles for older adults. …”
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