“…The fast-growing sector of insects for food and feed stimulates researchers and the industry to explore uncharted territories, such as insect breeding, to improve economically important insect fitness traits. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The effects of molecularly targeted therapies on imaging appearances remain uncharted. We investigated the imaging characteristics of brain metastasis during tyrosine kinase inhibitor (TKI) administration. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…New sensors and modulators that interact wirelessly with medical modalities unlock uncharted avenues for in situ brain recording and stimulation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…While there has been considerable research focused on the Ts65Dn mouse model of DS, particularly in the context of the hippocampus, the synaptic underpinnings of prefrontal cortex (PFC) dysfunction in DS, including deficits in working memory, remain largely uncharted territory. In a previous study featuring mBACtgDyrk1a mice, which manifest overexpression of the Dyrk1a gene, a known candidate gene linked to intellectual disability and microcephaly in DS, we documented adverse effects on spine density, alterations in the molecular composition of synapses, and the presence of synaptic plasticity deficits within the PFC. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Nuclear factors rapidly scan the genome for their targets, but the role of nuclear organization in such search is uncharted. Here we analyzed how multiple factors explore chromatin, combining live-cell single-molecule tracking with multifocal structured illumination of DNA density. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Whereas top-down attentional control is known to bias perceptual functions at many levels of stimulus analysis, its possible influence over memory-related functions remains uncharted. Our experiment combined behavioral measures and event-related potentials (ERPs) to test the ability of spatial orienting to bias functions associated with visual short-term memory (VSTM), and to shed light on the neural mechanisms involved. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Further investigations on SDIMOs genes in natural environments are necessary to unravel their still uncharted diversity and to provide reliable tools for the prospection of degrading populations.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Taken together, these results demonstrate that PHYRN represents a powerful mechanism for mapping uncharted frontiers in highly divergent protein sequence data sets.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These remarkably different conformations are considered to be end points of the substrate translocation path (STP), suggesting that the transport mechanism involves major conformational rearrangements that remain uncharted. To investigate possible steps in the structural transitions of the STP between the two end-point conformations, we applied a combination of computational modeling methods (motion planning, molecular dynamics simulations, and mixed elastic network models). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Despite their potential connection to the evolution of programmed cell death in eukaryotes, the phylogenetic distribution and functions of these prokaryotic metacaspase sequences are largely uncharted, while a few experiments imply involvement in programmed cell death. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Further applications of our approach in areas of complex diseases, treatment will provide uncharted potentials to researchers in the domains.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Viruses infecting prokaryotic cells (phages) are the most abundant entities of the biosphere and contain a largely uncharted wealth of genomic diversity. They play a critical role in the biology of their hosts and in ecosystem functioning at large. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Computational de novo design of new drugs and materials requires rigorous and unbiased exploration of chemical compound space. However, large uncharted territories persist due to its size scaling combinatorially with molecular size. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Previous studies suggested that Na(+)-binding reconfigures dynamically coupled structural elements in an allosteric interaction network (AIN) responsible for function-related conformational changes, but the intramolecular pathway of this mechanism has remained uncharted. We describe a new approach for the modeling and analysis of intramolecular dynamics in the bacterial NSS homolog LeuT. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our findings enable further genetic studies to elucidate the function of STIMATE in normal physiology and disease, and set the stage to uncover more uncharted functions of hitherto underexplored ER-PM junctions.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, the interplay between sleep and social cognition remains an uncharted research area. In particular, little is known about the impact of sleep deprivation on sarcasm detection, an ability which, once altered, may hamper everyday social interactions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Although numerous notochord genes have been identified, the regulatory DNAs that orchestrate development and propel evolution of this structure by eliciting notochord gene expression remain mostly uncharted, and the information on their configuration and recurrence is still quite fragmentary. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our findings shed light on hitherto uncharted features of the electronic structure of weak topological insulators and open up new vistas for applications of these materials in spintronics.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The key architecture of ASD development which could be a target for treatment is still an uncharted territory. Further work is needed to broaden the horizons on the understanding of ASD.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, the linkage between strengths self-efficacy, resourcefulness and mental health recovery remains uncharted. A cross-sectional, descriptive, mixed methods study will be conducted. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso