“…By learning these dependencies between sequences and functions, they can ultimately be used to generate new sequences and navigate through uncharted area of molecular evolution. RESULTS: This study presents an Adversarial Auto-Encoder (AAE) approached, an unsupervised generative model, to generate new protein sequences. …”
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“…Senior undergraduate or graduate students may also discover uncharted territory for their own research endeavors.…”
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“…With a cumulative luminosity of more than 100~fb$^{-1}$ collected at $\sqrt{s}=7,8,13$~TeV by each of the ATLAS and CMS experiments at the Large Hadron Collider in the first ten years of operation, top quark physics is probing uncharted territories in precision and rare measurements with sensitivity to New Physics processes. …”
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“…With a cumulative luminosity of more than 100~fb$^{-1}$ collected at $\sqrt{s}=7,8,13$ TeV by each of the ATLAS and CMS experiments at the Large Hadron Collider in the first ten years of operation, top quark physics is probing uncharted territories in precision and rare measurements with sensitivity to New Physics processes. …”
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“…Despite this, the underpinning mechanisms for progressive fibrotic sarcoidosis is an almost uncharted area. Consequently, there has been little change in the clinical management of fibrotic sarcoidosis over the decades and an unfocused search for new therapeutics. …”
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“…The experiment has already started the He-3 run based on solid grounds for further exploring uncharted but promising regions of phase space.…”
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“…The practicalities of broad data sharing remain largely uncharted, especially to cover the wide range of data types currently produced by genomic studies and to adequately address ethical issues. …”
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“…The important, and successful, SM physics measurements are giving confidence that the experiment is in good shape for their journey into the uncharted territory of new physics anticipated at the LHC.…”
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“…Inorganic confinement is a relatively uncharted domain in studies concerning prebiotic chemistry, and even more so in terms of experimentation. …”
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“…Andrea Paterlini is author of ‘Uncharted routes: exploring the relevance of auxin movement via plasmodesmata’, published in BiO. …”
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“…The important, and successful, SM physics measurements are giving confidence that the experiments are in good shape for their journey into the uncharted territory of new physics anticipated at the LHC.…”
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“…A broad spectrum of new research opportunities, in a vast domain of uncharted fundamental and applied physics territories, could be opened by the Gamma Factory. …”
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“…Having recently graduated early from medical school, we offer our reflections on the obstacles and opportunities associated with working in an uncharted clinical environment. We are not the only ones on a steep learning curve at this time: this pandemic will challenge and provide learning for staff of all levels.…”
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“…Structural correlations among protein chains are routinely detected by various structure-matching techniques, but the comparison of oligomers and molecular complexes is largely uncharted territory. Here we solve the structure-matching problem for oligomers and large molecular aggregates, including the largest molecular complexes known today. …”
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“…We summarize what is currently known about gB from two closely related herpesviruses, HSV-1 and HSV-2, with emphasis on the structure of the largely uncharted membrane interacting regions of this fusogen. …”
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“…Either way, a synthetic goal forces scientists to cross uncharted ground to encounter and solve problems that are not easily encountered through analysis. …”
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“…Public health disasters reflect the uncharted conceptual, ethical, and pragmatic intersections between public health ethics and the emerging discourse on disaster bioethics. …”
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“…We realized that there is no clear, published recommendations or scientific data to guide surgeons on how to discuss options with their patients and recommendations for surgical management in this uncharted territory. Using available literature and personal experience, we answer the most common questions we are hearing from our plastic surgery colleagues.…”
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“…Indeed, the applications of molecular technologies have taken NBS to previously uncharted territory. In this paper, based on our own program experience and what has been reported in the literature, we describe current practices regarding the applications of molecular technologies in routine NBS practice in the era of genomic and precision medicine.…”
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“…From the wonder of Gothic Cathedrals, to the quiet majesty of lighter than air flight, to the ultimate in luxury of the north Atlantic steamers, Peter Hancock explores how these sequential heights of technology have enabled our dreams of being transported to new and uncharted realms to become reality. Sometimes literally, sometimes figuratively, technology has always been there to make material the visions of our imagination. …”
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