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  1. 14701
    “…Based on the segregation data and independent reports, five known likely pathogenic variants and four VUS were upgraded to pathogenic variant and likely pathogenic variant respectively. …”
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    Identification of Novel Clinically Relevant Variants in 70 Southern Chinese patients with Thoracic Aortic Aneurysm and Dissection by Next-generation Sequencing
  2. 14702
    “…Employing an ultrafast p-i-n photodiode with smaller active area diameter and lower noise equivalent power significantly enlarges the data rate by 1.6 Gbps or upgrades the signal-to-noise ratio (SNR) by 0.2 dB. …”
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    Blue Laser Diode Based Free-space Optical Data Transmission elevated to 18 Gbps over 16 m
  3. 14703
    “…The results of the treatment by KH-204 (1) preserved TM3 cells from oxidative stress by improving the expression of nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1); (2) lowered the expression of transforming growth factor-beta (TGF-β) 1/SMAD; (3) increased the average of serum testosterone in androgen-deprived male rats; (4) kept the activation of spermatogenesis; (5) upgraded the contents of 8-hydroxy-20-deoxyguanosine (8-OHdG) and degraded the contents of superoxide dismutase (SOD); and (6) reduced apoptosis. …”
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    Antioxidant and Antifibrotic Effect of a Herbal Formulation In Vitro and in the Experimental Andropause via Nrf2/HO-1 Signaling Pathway
  4. 14704
    “…CONCLUSIONS: To reduce maternal deaths from unsafe abortion, several broad activities require strengthening such as decreasing unwanted pregnancies, increasing geographic accessibility and affordability, upgrading facilities that offers medical termination of pregnancy (MTP) services, increasing awareness among the reproductive age about the legal and safe abortion facilities, the consequences of unsafe abortion, ensuring appropriate referral facilities, increasing access to safe abortion services and increasing the quality of abortion care, including postabortion care.…”
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    Socio-clinical profile of married women with history of induced abortion: A community-based cross-sectional study in a rural area
  5. 14705
    por Ban, Young Ho, Ha, Sang-Jun
    Publicado 2017
    “…We revealed several new advantages of SFQF assay, which overcomes some of the previously contentious points, and established an upgraded version of the previously reported flow cytometric titration assay. …”
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    Semi-Functional Quantitative Flow Cytometry Assay for Lymphocytic Choriomeningitis Virus Titration
  6. 14706
    “…Among the 23 reviews, the Gleason score changed for 8 (35%) patients: 7 upgraded and 1 downgraded. The new Gleason score affected the treatment decision in 5 of 8 cases (62.5%). …”
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    Impact of Pathology Review for Decision Therapy in Localized Prostate Cancer
  7. 14707
    por Verma, Anand Mohan, Kishore, Nanda
    Publicado 2017
    “…Therefore, it has to be upgraded prior to its use as transportation fuel. In this work, guaiacol, a promising compound of the phenolic fraction of unprocessed bio-oil, is considered as a model component for studying its hydrodeoxygenation over a Pt(3) catalyst cluster. …”
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    Platinum catalyzed hydrodeoxygenation of guaiacol in illumination of cresol production: a density functional theory study
  8. 14708
    “…The Linac Coherent Light Source is upgrading its machine to high repetition rate and to extended ranges. …”
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    Damage thresholds for blaze diffraction gratings and grazing incidence optics at an X-ray free-electron laser
  9. 14709
    por Zheng, Alvin, Cao, Xiaoyi, Zhong, Sheng
    Publicado 2017
    “…GeNemo returns a list of genomic regions with matching patterns to the input data, which may be viewed in the browser as well as downloaded in the BED file format. The upgraded GeNemo has improved graphical display, has more robust interface, and is no longer prone to errors due to changes in the University of California, Santa Cruz (UCSC) genome browser. …”
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    Pattern-based Search of Epigenomic Data Using GeNemo
  10. 14710
    “…As a community portal, Gramene integrates best-of-class software and infrastructure components including the Ensembl genome browser, Reactome pathway browser, and Expression Atlas widgets, and undergoes periodic data and software upgrades. Via powerful, intuitive search interfaces, users can easily query across various portals and interactively analyze search results by clicking on diverse features such as genomic context, highly augmented gene trees, gene expression anatomograms, associated pathways, and external informatics resources. …”
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    Gramene 2018: unifying comparative genomics and pathway resources for plant research
  11. 14711
    “…Antimicrobial resistance proteins have been reannotated comprehensively, improved structural annotation of insertion sequence transposases and selenoproteins is provided, curated complex domain architectures have given upgraded names to millions of multidomain proteins, and we introduce a new kind of annotation rule—BlastRules. …”
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    RefSeq: an update on prokaryotic genome annotation and curation
  12. 14712
    “…CONCLUSION: Hospital pharmacy practitioners’ opinions and suggestions were assessed with respect to the CPE program and this was upgraded accordingly to meet their expectations.…”
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    Opinion of hospital pharmacy practitioners toward the Continuing Pharmacy Education program: a study from a tertiary care hospital in central Nepal
  13. 14713
    “…We present the full characterization of an upgraded version of Jazz gene named “JZif1” designed to minimize any possible host immune response. …”
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    Utrophin up-regulation by artificial transcription factors induces muscle rescue and impacts the neuromuscular junction in mdx mice
  14. 14714
    “…With the large number of beamports and the space below the target available for future moderators, ample opportunities are available for future upgrades.…”
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    Optimization of moderators and beam extraction at the ESS
  15. 14715
    “…After a diagnosis of ADH on biopsy a proportion are upgraded to carcinoma upon excision; however, the remainder of patients are overtreated. …”
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    Atypical ductal hyperplasia: update on diagnosis, management, and molecular landscape
  16. 14716
    “…RESULTS: Oleic acid and β-cyclodextrin upgraded the levels of dopamine, 5-HIAA and lipid peroxidation and downgraded the concentrations of GSH and H(2)O(2) in cortex, hemispheres (striatum) and cerebellum/medulla oblongata regions. …”
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    β-Cyclodextrin and oleic acid increase levels of dopamine and potentiates oxidative damage in young and adult rat brain
  17. 14717
    por Zhao, Tong, Song, Zhijie, Li, Tianjiao
    Publicado 2018
    “…Manufacturing in China has developed rapidly with the widening and deepening of globalization, but only innovation can industry keep upgrading and enhancing its international competitiveness. …”
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    Effect of innovation capacity, production capacity and vertical specialization on innovation performance in China's electronic manufacturing: Analysis from the supply and demand sides
  18. 14718
    por Liljedahl, Matilda
    Publicado 2018
    “…The main message in the thesis argued for an upgrading of students as a powerful and active stakeholder in workplace learning, so as not to view students as passive consumers of clinical education.…”
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    On learning in the clinical environment
  19. 14719
    “…Conclusion: Planning for modification of physical stressors, improved support of patients, enhancing the quality of care services provided by the treatment team, upgrading the facilities and equipment and the adoption of an interdisciplinary approach are all believed to improve the care services among in-patients receiving hemodialysis treatment.…”
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    Improving Quality of Care in Hemodialysis: a Content Analysis
  20. 14720
    “…However, SAR-stressed plants treated by melatonin exhibited upgradation on the fruit quality traits, antioxidant compounds and yield attributes through accelerating oxidant-scavenging antioxidant actions in fruits compared with fruits of SAR-stressed plants. …”
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    Exogenous Melatonin Improves Fruit Quality Features, Health Promoting Antioxidant Compounds and Yield Traits in Tomato Fruits under Acid Rain Stress
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