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  1. 15821
    “…We included inborn neonates requiring initiation or upgradation of antibiotics for a diagnosis of sepsis, from 1 May to 30 November 2018. …”
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    Ensuring administration of first dose of antibiotics within the golden hour of management in neonates with sepsis
  2. 15822
    “…The study provides important insights on buffalo breeds of North India that could be utilized in designing an effective breeding strategy, with an appropriate choice of breeds for upgrading local non-descript buffaloes along with conservation of unique germplasm.…”
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    Morphometric and microsatellite-based comparative genetic diversity analysis in Bubalus bubalis from North India
  3. 15823
    “…Of lesions observed, 180 (39.4%) showed upgraded histology. Multivariate analysis revealed that surface erythema (odds ratio [OR], 2.804; 95% confidence interval [CI], 1.741 to 4.516), spontaneous bleeding (OR, 2.618; 95% CI, 1.298 to 5.279), lesion size ≥ 1 cm (OR, 5.762; 95% CI, 3.459 to 9.597), and depressed morphology (OR, 2.183; 95% CI, 1.155 to 4.124) were significant risk factors for high-grade dysplasia or adenocarcinoma. …”
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    Risk stratification of patients with gastric lesions indefinite for dysplasia
  4. 15824
    “…Final pathology demonstrated that 42.8% (6/14) of the patients had nonorgan confined disease (pT3a/T3b). 50% (7/14) of the patients were upgraded to higher risk Gleason disease on final surgical pathology. …”
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    Oncological and Functional Outcomes of Robot-Assisted Radical Prostatectomy in Kidney Transplant Recipients
  5. 15825
    “…The post-treatment battery was upgraded with three additional tests: the novel object recognition task, the Barnes maze test, and the touchscreen-based paired-associated learning task. …”
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    Lack of direct involvement of a diazepam long-term treatment in the occurrence of irreversible cognitive impairment: a pre-clinical approach
  6. 15826
    “…One patient had no residual cancer, and the other was upgraded to invasive ductal carcinoma (IDC). Two patients with IDC underwent breast-conserving surgery and mastectomy with sentinel lymph node biopsy. …”
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    Visualization positioning-guided biopsy of suspicious breast microcalcifications: a retrospective cohort study
  7. 15827
    “…CONCLUSIONS: Electroanatomic voltage mapping–guided EMB was safe and yielded an optimal diagnostic yield. It allowed upgrading of the diagnosis of nearly one‐third of the patients considered “at risk.” …”
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    Endomyocardial Biopsy: The Forgotten Piece in the Arrhythmogenic Cardiomyopathy Puzzle
  8. 15828
    “…Upstaging from <pT1 in endoscopic biopsy to ≥pT1 in final pathology occurred in 61% of patients and upgrading from low-grade to high-grade occurred in 30% of patients. …”
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    Evaluation of Pre-operative Biopsy, Surgical Procedures and Oncologic Outcomes in Upper Tract Urothelial Carcinoma (UTUC)
  9. 15829
    por Xu, Gang, Wang, Qinghua, Ma, Jianpeng
    Publicado 2021
    “…RESULTS: OPUS-TASS2 is an upgraded version of our previous method OPUS-TASS. …”
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    OPUS-X: an open-source toolkit for protein torsion angles, secondary structure, solvent accessibility, contact map predictions and 3D folding
  10. 15830
    “…Stakeholders should consider upgrading snakebite care and antivenom supply during humanitarian crises in snakebite-endemic countries.…”
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    Snakebite envenoming in humanitarian crises and migration: A scoping review and the Médecins Sans Frontières experience
  11. 15831
    “…Details of these database features, how they are implemented and plans for future upgrades are also provided. The NP-MRD is available at https://np-mrd.org.…”
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    NP-MRD: the Natural Products Magnetic Resonance Database
  12. 15832
    “…These are currently being addressed by e.g., upgrading the KLIK website, implementing PROMIS item banks in KLIK to reduce irrelevancy and repetitiveness of PROMs, and implementation strategies to improve the discussion-rate. …”
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    Patients’ and parents’ perspective on the implementation of Patient Reported Outcome Measures in pediatric clinical practice using the KLIK PROM portal
  13. 15833
    “…Over the study period, only one VUS variant was upgraded to “likely positive.” The recent introduction of multiple-gene panel testing had resulted in a surge in VUS rate (22.2%) in genes other than BRCA1 or BRCA2, like PALB2, CHEK2, and ATM. …”
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    Rates of Variants of Uncertain Significance Among Patients With Breast Cancer Undergoing Genetic Testing: Regional Perspectives
  14. 15834
    “…PSA significantly inhibits CO(2) emissions, but heterogeneous influences exist in different regions, time nodes, and sub-industries; (2) PSA can indirectly curb CO(2) emissions through economies of scale, technological innovation, and industrial structure upgrading. (3) The impact of PSA on China’s CO(2) emissions has an obvious double threshold effect under different degree of government intervention. …”
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    Does government intervention affect CO(2) emission reduction effect of producer service agglomeration? Empirical analysis based on spatial Durbin model and dynamic threshold model
  15. 15835
    “…Besides Gleason Score upgrading, the maximum number of positive cores were the most frequent exclusion criterion. …”
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    Active surveillance inclusion criteria under scrutiny in magnetic resonance imaging-guided prostate biopsy: a multicenter cohort study
  16. 15836
    “…AR aids in surgery planning, and patient therapy discloses complex medical circumstances to patients and their family members. With accelerated upgrades in innovation, the ever-increasing number of medical records get accessible, which contain a lot of sensitive medical data, similar to medical substances and relations between them. …”
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    Medicine Drug Name Detection Based Object Recognition Using Augmented Reality
  17. 15837
    “…Among these cases, 80 cases (30%) upgraded the inconclusive diagnosis to a definite diagnosis, and 60 cases (22%) changed the diagnosis with major or minor discordance, accounting for 28 cases (10%) and 32 cases (12%), respectively. …”
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    Substantial improvement of histopathological diagnosis by whole-slide image-based remote consultation
  18. 15838
    “…Furthermore, S1R activation protects RV function by upgrading the NRF 2/HO 1-mediated antioxidant stress pathway. …”
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    Chronic Sigma 1 receptor activation alleviates right ventricular dysfunction secondary to pulmonary arterial hypertension
  19. 15839
    “…And the specificity was 93.8%, and the negative predictive value was 96.4%. The upgraded nomogram improved the predictive accuracy, using only US and PET/CT. …”
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    A nomogram for predicting three or more axillary lymph node involvement before breast cancer surgery
  20. 15840
    “…(vi) Suppliers of products that do not fulfil the new regulation will disappear, and the availability of consumables, spare parts or upgrades might be discontinued. (vii) A trend to oligopoly may appear in the market. …”
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    New regulation of medical devices in the EU: impact in dermatology
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