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Mostrando 981 - 1,000 Resultados de 1,763 Para Buscar '"Usher"', tiempo de consulta: 0.12s Limitar resultados
  1. 981
    “…Advances in molecular and immunohistochemical techniques have made it possible to usher lung cancer into the era of personalized medicine, with the patient getting individualized treatment based on these markers. …”
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    Targeted therapy in advanced non-small cell lung cancer: current advances and future trends
  2. 982
    “…An increased understanding of the potential of Salmonella bacteria in combination cancer therapy may usher in a major breakthrough in its clinical application, resulting in more favorable and durable outcomes. …”
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    Integration of Salmonella into Combination Cancer Therapy
  3. 983
    “…Ensemble Förster resonance energy transfer studies show that Puf6 mimics the role of Mg(2+) to usher a unique long-range tertiary contact to compact rRNA. …”
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    Puf6 primes 60S pre-ribosome nuclear export at low temperature
  4. 984
    “…Disorders being targeted for genetic therapy include retinitis pigmentosa (RP), choroideremia (CHM), achromatopsia (ACHM), Leber’s hereditary optic neuropathy, usher syndrome (USH), X-linked retinoschisis, and Stargardt disease. …”
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    Gene therapy for inherited retinal diseases
  5. 985
    “…As time spent at home has significantly increased during the pandemic, reports of household conflict has also risen among people living with others (Usher et al., 2020). One solution to alleviate the potential stress of increased time with others could be carving out time to oneself. …”
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    The Role of Relationship Quality for Solitude Experiences during the Pandemic
  6. 986
    “…The recognition of the role of AMH beyond gonadal development and maturation may usher in novel diagnostic and therapeutic applications that would further expand its utility in pediatric care.…”
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    Clinical Utility of Anti-Mullerian Hormone in Pediatrics
  7. 987
    por Heng, Julie, Heng, Henry H.
    Publicado 2021
    “…We hope that these ideas will usher in new genomic and evolutionary conceptual frameworks and strategies for the next 50 years of cancer research.…”
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    Genome Chaos, Information Creation, and Cancer Emergence: Searching for New Frameworks on the 50th Anniversary of the “War on Cancer”
  8. 988
    “…RESULTS: We report eight pathogenic variants, four of which are novel in patients with isolated hearing impairment, hearing impairment, and renal tubular acidosis, Usher syndrome and Pendred syndrome. Functional studies using molecular modeling showed the severe impact of the novel missense mutations on the concerned proteins. …”
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    Custom Next‐Generation Sequencing Identifies Novel Mutations Expanding the Molecular and clinical spectrum of isolated Hearing Impairment or along with defects of the retina, the thyroid, and the kidneys
  9. 989
    “…We found that, under subinhibitory concentrations of antibiotics, A. baumannii upregulates expression of the paa operon while simultaneously repressing chaperone-usher Csu pilus expression and biofilm formation. …”
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    The Phenylacetic Acid Catabolic Pathway Regulates Antibiotic and Oxidative Stress Responses in Acinetobacter
  10. 990
    por Saxena, Sudhanshu, Gautam, Satyendra
    Publicado 2022
    “…Selectively up-regulated characterized using MALDI-TOF MS/MS were identified as polyribonucleotide nucleotidyl transferse (PNPase), LPS-assembly lipoprotein (LptE), Outer membrane Usher protein (HtrE), ATP-dependent DNA helicase (RecG), and Phosphomethyl pyrimidine synthase (ThiC). …”
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    Molecular events confirming antimutagenicity to abscisic acid derived from a floral honey establishing its functional relevance
  11. 991
    “…Mutations in the ABCA4, PRPH2, USH2A, BEST1, RР1, CDHR1, and RHO genes were detected reaching a diagnostic yield between 42.9% for Retinitis pigmentosa cases and 100% for macular degeneration, Usher syndrome, and cone‐rod dystrophy patients. …”
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    Panel‐based next‐generation sequencing identifies novel mutations in Bulgarian patients with inherited retinal dystrophies
  12. 992
    “…The introduction of modern methods and neoantigen-based immunotherapy may usher in a new era in treating CRC. The unmet goal is to better understand the cellular and molecular mechanisms that contribute to CRC pathogenesis and resistance to treatment, identify novel therapeutic targets, and make more stratified and informed treatment decisions using single cell approaches. …”
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    Deciphering colorectal cancer immune microenvironment transcriptional landscape on single cell resolution – A role for immunotherapy
  13. 993
    “…The most prevalent dystrophies identified clinically were non-syndromic retinitis pigmentosa (29.8%), Stargardt disease (8.3%), Usher syndrome (8.3%), cone-rod dystrophy (8.0%), cone dystrophy (4.9%), and Leber congenital amaurosis (4.3%). …”
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    Inherited Retinal Dystrophy in Southeastern United States: Characterization of South Carolina Patients and Comparative Literature Review
  14. 994
    “…AI approaches can revolutionize personalized treatments and usher in better-informed clinical trials. They promise to make giant leaps toward reshaping and revamping drug discovery strategies, selecting and prioritizing combinations of drug targets. …”
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    AlphaFold, Artificial Intelligence (AI), and Allostery
  15. 995
    “…We think that this new approach will reveal a population with hyperreactive platelets who will benefit most from primary CVD prevention with aspirin and usher in a new era of precision-guided antiplatelet therapy.…”
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    Aspirin for the Primary Prevention of Cardiovascular Disease: Time for a Platelet-Guided Approach
  16. 996
    “…Non-canonical splice site variants are increasingly recognized as a relevant cause of the USH2A-associated diseases, non-syndromic autosomal recessive retinitis pigmentosa and Usher syndrome type 2. Many non-canonical splice site variants have been reported in public databases, but an effect on pre-mRNA splicing has only been functionally verified for a subset of these variants. …”
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    Minigene-Based Splice Assays Reveal the Effect of Non-Canonical Splice Site Variants in USH2A
  17. 997
    “…(Arg5246*), which suggests the Usher syndrome type 2C and the reason for sensorineural hearing loss in this case. …”
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    A rare presentation of Carnitine palmitoyltransferase II (CPT-2) deficiency with normal acylcarnitine profile in a 10-year-old boy with muscle weakness and bilateral hearing loss; a case report
  18. 998
    por K, Rajashree, Singai, Chetan
    Publicado 2022
    “…Laws and legal institutions need to be simplified while improving the overall accessibility to justice for senior citizens. There is a need to usher in systemic changes to protect senior citizens through an inclusive legal system. …”
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    Reforms in legal aid and awareness with regard to the aged in India: A case for an inclusive approach
  19. 999
    “…Thread subunits are interconnected via donor strand complementation, a feature reminiscent of bacterial chaperone-usher pili. However, despite these similarities in overall architecture, archaeal threads appear to have evolved independently and are likely assembled by a distinct mechanism.…”
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    Electron cryo-microscopy reveals the structure of the archaeal thread filament
  20. 1000
    “…Meanwhile, the tensile strength and tear strength of EPDM/AEG composites are much higher than neat EPDM, therefore, with the future development of innovate reinforcing-type flame-retardant Enteromorpha, the application of Enteromorpha in the polymer flame-retardant field will surely usher in bright development.…”
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    The Study of Enteromorpha-Based Reinforcing-Type Flame Retardant on Flame Retardancy and Smoke Suppression of EPDM
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